Mono and PSC

[Guest guest]

I noticed the posts in regards to PSC and hernias. Here's another question:

How many ever had mono--which, as we know, causes LFTs to be elevated. My

husband Fred contracted mono at age 30. (We had just gotten married, and he

slept through the honeymoon.)

,

Wife of Fred, PSC 03/04 and doing well. (By the way, he's been on fish oil

for YEARS, which hopefully, has helped slow down the PSC.)

[Guest guest]

I had mono about 12 years ago. Not too bad a case. But I too thought I would never get my energy back.

Ali

-Recycle yourself -

Become an Organ and Tissue Donor

Ali Lingerfelt-Tait

alisoikias@...

***** my new address and phone number are:

180 Blackberry Inn Rd.

Weaverville, N.C. 28787

828 658-8019

[Guest guest]

I had Mono when I was 47, I worked as a secretary at the high school and got it

there, from water fountains I guess. I thought I would never get over it. I

didn't realize it could raise your liver enzymes, who knows maybe it has

contributed to PSC in some way. I wasn't diagnosed until age 68, but I am sure

I had it for several years before that. An interesting theory.

Martha from Mo.

[Guest guest]

Yep, personally had a REALLY bad case of mono................it will be interesting to see how many of us out there have had mono.............survey says.........__________________________________________________

[Guest guest]

Never had mono.

Arne

53 - UC 9/77 - PSC 4/00

Alive and (mostly) well in Minnesota

-----Original Message-----

From: [mailto: ] On

Behalf Of Hussey

I noticed the posts in regards to PSC and hernias. Here's another question:

How many ever had mono--which, as we know, causes LFTs to be elevated. My

husband Fred contracted mono at age 30. (We had just gotten married, and he

slept through the honeymoon.)

,

Wife of Fred, PSC 03/04 and doing well. (By the way, he's been on fish oil

for YEARS, which hopefully, has helped slow down the PSC.)

[Guest guest]

I've never had mono.

Barby -KSUC - 1965, ileostomy - 1972, BCIR (continent pouch) 1994, PSC - 1995 married 25 years, 5 sons, 1 daugher in law and 2 golden retrievers

[Guest guest]

I had Mono when I was 14 yrs. old. Got diagnosed in 2003 with MS and

PSC in June 2004. I've always wondered if that Mono bug is more

harmful than we ever thought!

Liz MS 2/03 PSC 6/04

> I noticed the posts in regards to PSC and hernias. Here's another

question:

> How many ever had mono--which, as we know, causes LFTs to be

elevated. My

> husband Fred contracted mono at age 30. (We had just gotten married,

and he

> slept through the honeymoon.)

>

> ,

> Wife of Fred, PSC 03/04 and doing well. (By the way, he's been on

fish oil

> for YEARS, which hopefully, has helped slow down the PSC.)

[Guest guest]

Dear ;

I agree with you that there is a possible link between mononucleosis

(Epstein-Barr virus) and multiple sclersosis (see for example):

Goldacre MJ, Wotton CJ, Seagroatt V, Yeates D. Multiple sclerosis

after infectious mononucleosis: record linkage study.

J Epidemiol Community Health. 2004 Dec;58(12):1032-5.

PMID: 15547068.

Cepok S, Zhou D, Srivastava R, Nessler S, Stei S, Bussow K, Sommer N,

Hemmer B. Identification of Epstein-Barr virus proteins as putative

targets of the immune response in multiple sclerosis.

J Clin Invest. 2005 May;115(5):1352-60. Epub 2005 Apr 14.

PMID: 15841210.

Earlier (perhaps as long as a year ago, or more?), we discussed the

idea that Epstein-Barr virus might trigger autoimmune hepatitis in

susceptible individuals:

Vento S, Guella L, Mirandola F, Cainelli F, Di Perri G, Solbiati M,

Ferraro T, Concia E. Epstein-Barr virus as a trigger for autoimmune

hepatitis in susceptible individuals. Lancet. 1995 Sep 2;346

(8975):608-9. PMID: 7651006.

It's proposed that autoimmune hepatitis can " evolve " into PSC:

Abdo AA, Bain VG, Kichian K, Lee SS. Evolution of autoimmune

hepatitis to primary sclerosing cholangitis: A sequential syndrome.

Hepatology. 2002 Dec;36(6):1393-9. PMID: 12447864.

So Epstein-Barr virus should not be over-looked as a possible (but

maybe not the only) " trigger " in MS, autoimmune hepatitis and PSC.

Best regards,

Dave

(father of (19); PSC 07/03; UC 08/03)

> I guess that debunk's my theory! However, I'm still

> investigating the possible link between Mono and Multiple

Sclerosis -

> probably no link, but they do think that a virus triggers it and

many

> MS sufferers have had MS. Thanks for your post.

[Guest guest]

I never

had mono. My mother had lots of gastro problems when I was very young. She was

hospitalized at Duke before I was born and after I was born had some stomach(?)

surgery, but that is the sum total of my knowledge. I left when I was 16 so I don’t

really know much about all that.

Sam

PSC ’01,

listed ’03 and again ‘04

-----Original

Message-----

From:

[mailto: ]On Behalf

Of Hussey

Sent: Thursday, May 05, 2005 4:59

PM

To:

Subject: Mono and

PSC

I noticed the posts in regards to PSC and hernias. Here's another

question:

How many ever had mono--which, as we know, causes LFTs to be elevated. My

husband Fred contracted mono at age 30. (We had just gotten married, and he

slept through the honeymoon.)

,

Wife of Fred, PSC 03/04 and doing well. (By the way, he's been on fish oil

for YEARS, which hopefully, has helped slow down the PSC.)