Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 (((((((((()))))))) These abnormalities are what caused the neurologist to send me to an oncologist as they thought I had Multiple Myloma(spelling*)due to the irregularities. The oncologist did not think so, but He wanted to keep a close check in case I did develop that.(Which, BTW was considered an auto-immune disease before classified as a blood cancer)The oncologist then sent me to get checked for AS.The skeletal x-rays proved negative. When I was in the hospital with a hg of 8, I too, have been a red meat eater,and spinach. Hugs, Feisty > When my CBCs suddenly popped up with screwed up values for the RBCS, the MCV, MCHC, and some others, I got busy finding out what the difference was between all these anemias, since my ferritin and serum iron were very good, but not ridiculously high. This was the first time that I had to cope with this one, through all my yrs of having babies, and the first yrs of hypo-hyper with Hashi's. From all these articles that I had posted on the sbjct, they all said that long ongoing hypothyroidism could eventually cause this. It didn't appear in my general testing with HealthCheck until the first week of this March. I had been having problems with adjustment of the Armour for probably 6 months before that, just now discovered the high Hashi's antibodies, and I know that I was undertreated with synthetics during the last 4 or 5 yrs. It did say that these two types of anemias (B12 and Folic Acid) would not appear in the blood work until there was already a critical problem. These two tests are not part of a routine CBC, you have to run them separately, if the doc even thinks to run them with our complaints of fatigue, brain fog, etc....It frightened me to the point of researching the anemias, which I knew nothing about before this (other than iron anemia). It said in every article I went to that, any ongoing chronic disease could eventually cause this, but who would think to have these two tests run, unless you already know it!? Mine ended up not being the B12, rather the Folic Acid. What's scary is that we can have one or both of these two anemias for 10-30 yrs, without them ever registering on our CBCs. When they finally do, it's pretty darn serious stuff! I'm taking around 1000 mcgs of liquid B12, and double the requirements of Folic Acid, just to make sure. Then, when I get my testing again, I will see whether I need to cut back on either one of them. If we are unsure of the lab value of B12, there is another test that can help determine it, something called malomalonic? Also, the homocysteine value helps determine whether we might need more Folic Acid, if we're unsure of the serum and RBC Folate values. With a B12 shortage, I would also opt for testing for the antibody to parietal cells and intrinsic factor, just in case it was caused by absorption problems there in the gut. It puzzled me that it could be the B12, unless it was an absorption problem, because I am a strong red meat eater. The Folic Acid I took very seriously because I do not like to eat tons of green veggies, at least not enough to cover a shortage, but you can bet your bippie that I got busy eating them then!! > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Hmmm. Wonder if your circulating anemia is related to hypo. SO many mysteries, here!! Janie > I am one that has been dxed with Hemolytic anemia. > Feisty Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 Your post contains very crucial info, !! I am amazed. And what just ticks me off after reading it is that I spent 17 miserable years on INADEQUATE treatment (synthroid/levoxyl), which is NO different in my eyes to what you said about " ongoing chronic disease " . And which could be what has screwed up my Ferritin, EVEN when I am on an optimal dose of Armour!!! There is an absorption issue going on here with many of us. Makes me wonder if I should get my B-12 and Folic acid tested....hmmmmm Janie >It said in every article I went to that, any ongoing chronic disease >could eventually cause this, but who would think to have these two >tests run, unless you already know it!? Mine ended up not being the >B12, rather the Folic Acid. What's scary is that we can have one or >both of these two anemias for 10-30 yrs, without them ever >registering on our CBCs. When they finally do, it's pretty darn >serious stuff! I'm taking around 1000 mcgs of liquid B12, and >double the requirements of Folic Acid, just to make sure. Then, >when I get my testing again, I will see whether I need to cut back >on either one of them. If we are unsure of the lab value of B12, >there is another test that can help determine it, something called >malomalonic? Also, the homocysteine value helps determine whether >we might need more Folic Acid, if we're unsure of the serum and RBC >Folate values. With a B12 shortage, I would also opt for testing >for the antibody to parietal cells and intrinsic factor, just in >case it was caused by absorption problems there in the gut. It >puzzled me that it could be the B12, unless it was an absorption >problem, because I am a strong red meat eater. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2004 Report Share Posted May 12, 2004 This is why I did so many posts on anemia, after I discovered my own. I had no idea that this could be such a problem with hypo that has been there awhile,i.e., you could have knocked me over with a feather! Let me look for those links, but you can google " different types of anemia with hypothyroidism " and probably come up with oodles of them. The deal is that the problem probably doesn't appear right away, but because of the length of illness, the body eventually slows down the transport of the oxygen to the cells, causing the hemoglobin to wax and wane, with iron anemia. Same thing with B12 and Folate, except, with B12, it's either going to be a case of never eating red meat, OR, as you said, autoimmune antibodies attacking the intrinsic factor or the rest of the gut (Celiac type illness). Some of the links sort of suggested which came first, the chicken or the egg---did the nutritional shortages help cause the thyroid problems or did the thyroid hormone shortage help form the anemias? I don't think it's always clear which one, and we know that thyroid disease has a huge mixture of causes, anyway. Re: Ferritin/Anemia--THIS IS INTERESTING Your post contains very crucial info, !! I am amazed. And what just ticks me off after reading it is that I spent 17 miserable years on INADEQUATE treatment (synthroid/levoxyl), which is NO different in my eyes to what you said about " ongoing chronic disease " . And which could be what has screwed up my Ferritin, EVEN when I am on an optimal dose of Armour!!! There is an absorption issue going on here with many of us. Makes me wonder if I should get my B-12 and Folic acid tested....hmmmmm Janie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 14, 2004 Report Share Posted May 14, 2004 mine is caused from low folic acid. My b-12 was a bit low but not as much as folic acid Re: Ferritin/Anemia--THIS IS INTERESTING HMMMM! This struck me, since I JUST read that a deficiency in two critical vitamins, folic acid and vitamin B-12, can cause anemia. And for me, it's been STRANGE that even on an optimal dose of Armour, I am forced to stay on iron, and a LOT of iron, DAILY to keep my Ferritin from dropping. HMMMMMMM Janie > There is a further link between anaemia and thyroid disease in that > people with autoimmune thyroid disease may also be likely to have > other > autoimmune disorders including pernicious anaemia, where there are > antibodies to cells in the stomach and the substance produced by > those > cells (anti-parietal cell antibodies and anti-intrinsic factor > antibodies) which may cause reduced vitamin B12 absorption. Quote Link to comment Share on other sites More sharing options...
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