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A Technical Question

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A technical question for everyone -

I read that when mast cells degranulate in response to

an allergic reaction - one of the chemicals released

in addition to histamine is serotonin.

Does anyone know what role serotonin plays in the

process?

What is the effect of having too much or not enough

serotonin in the body?

What about the role of prostaglandins in mast cell

degranulation?

I am trying desperately to find answers to this

urticaria puzzle and so right now I am playing

pathologist. I am reading through every piece of

information I can regarding anything and everything to

do with urticaria and the allergic or non allergic

response. I will not accept that there is no known

cause.

-Sheryl

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