Re: Sonnet: URT & RENAL FAILURE

[Guest guest]

Thank-you so much for all of the information I have received. My husband thinks I'm crazy, but I know I'm not. I keep telling him our Dr. doesn't have time to do research all day. The tools are there for us to use, and I have always said God has given us an incredible mind, and we need to use it. He will help us, but we need to do our part too. Again I thank you with all my heart for your help.

Sonnet

Sonnet: URT & RENAL FAILURE

Here are some med studies and articles....... you may want to check out these various subjects......... including Muckle-Wells syndrome. BIG hugs, Myra

Am J Hum Genet 2000 May;66(5):1693-8

Identification of a locus on chromosome 1q44 for familial cold urticaria.Hoffman HM, FA, Broide DH, Wanderer AA, Kolodner RDDepartment of Medicine, University of California at San Diego, La Jolla, CA 92093, USA. hahoffman@....Familial cold urticaria (FCU) is a rare autosomal dominant inflammatory disorder characterized by intermittent episodes of rash with fever, arthralgias, conjunctivitis, and leukocytosis. These symptoms develop after generalized exposure to cold. Some individuals with FCU also develop late-onset reactive renal amyloidosis, which is consistent with Muckle-Wells syndrome. By analyzing individuals with FCU from five families, we identified linkage to chromosome 1q44. Two-point linkage analysis revealed a maximum LOD score (Zmax) of 8.13 (recombination fraction 0) for marker D1S2836; multipoint linkage analysis identified a Zmax of 10. 92 in the same region; and haplotype analysis defined a 10.5-cM region between markers D1S423 and D1S2682. Muckle-Wells syndrome was recently linked to chromosome 1q44, which suggests that the two disorders may be linked to the same locus.PMID: 10741953, UI: 20311552 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Hautarzt 1980 Dec;31(12):633-8

[Cryoproteinemias].[Article in German]Landthaler MBiochemical cryoproteins are divided in cryoglobulins (type I-III), plasma-cryoproteins (heparin precipitable factor, cryofibrinogen and cryofibrin), and fibronectin. While cryoglobulinemias and plasma-cryoproteinemias are mainly caused by internal diseases, fibronectin may be a physiological substance. Because of skin lesions as purpura, necrosis or cold urticaria the patients rather often consult dermatologists at first. Furthermore arthralgias, kidney diseases, neurologic symptoms and lung involvement can be observed. For diagnosis a accelerated blood sedimentation rate at 37 degrees C and a decelerated at 4 degrees C is helpful. By further investigations underlying internal diseases have to be disclosed. In the therapeutical efforts the treatment of the underlying diseases is most important. Additional plasmapheresis and immunsuppressive treatment may be successful.Publication Types:

Review PMID: 7009493, UI: 81141497

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Intern Med 1992 Jan;31(1):94-7

Hereditary angioedema complicated with chronic renal failure: report of sibling cases.Nomura H, Tsugawa Y, Koni I, Tofuku Y, Mabuchi H, Takeda R, Sato TSecond Department of Internal Medicine, School of Medicine, Kanazawa University, Japan.Hereditary angioedema (HAE) is known as a deficiency state of C1 inhibitor (C1 INH), an important protease inhibitor protein involved in the complement system. As with other components of the classical pathway of the complement system, a state of its deficiency often causes clinical immunoregulatory disorders. A 45-yr-old brother and a 63-yr-old sister with HAE both developed chronic renal failure, probably due to chronic glomerulonephritis, and required regular hemodialysis. This is, to our knowledge, the first report of sibling cases of HAE associated with chronic renal failure.PMID: 1568052, UI: 92233009 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~If you do wish to unsubscribe then you can click on the following link: <mailto:urticaria-unsubscribeegroups>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~This list is in the service of those who suffer from Chronic Urticaria (hives). We strive to support and lift each other as a worldwide cyber-family. We share whatever needs to be shared to help one another in our struggle with Chronic Urticria. Any posting that is off the main topic of Chronic Urticaria, we post with a prefix of NCU -. This is done out of respect for those who do not wish to read such postings.

[Guest guest]

Myra, recently you gave a link to check out what blood test results mean, I have misplaced the link could you please send it again. Thank You so much~

Sonnet: URT & RENAL FAILURE

Here are some med studies and articles....... you may want to check out these various subjects......... including Muckle-Wells syndrome. BIG hugs, Myra

Am J Hum Genet 2000 May;66(5):1693-8

Identification of a locus on chromosome 1q44 for familial cold urticaria.Hoffman HM, FA, Broide DH, Wanderer AA, Kolodner RDDepartment of Medicine, University of California at San Diego, La Jolla, CA 92093, USA. hahoffman@....Familial cold urticaria (FCU) is a rare autosomal dominant inflammatory disorder characterized by intermittent episodes of rash with fever, arthralgias, conjunctivitis, and leukocytosis. These symptoms develop after generalized exposure to cold. Some individuals with FCU also develop late-onset reactive renal amyloidosis, which is consistent with Muckle-Wells syndrome. By analyzing individuals with FCU from five families, we identified linkage to chromosome 1q44. Two-point linkage analysis revealed a maximum LOD score (Zmax) of 8.13 (recombination fraction 0) for marker D1S2836; multipoint linkage analysis identified a Zmax of 10. 92 in the same region; and haplotype analysis defined a 10.5-cM region between markers D1S423 and D1S2682. Muckle-Wells syndrome was recently linked to chromosome 1q44, which suggests that the two disorders may be linked to the same locus.PMID: 10741953, UI: 20311552 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Hautarzt 1980 Dec;31(12):633-8

[Cryoproteinemias].[Article in German]Landthaler MBiochemical cryoproteins are divided in cryoglobulins (type I-III), plasma-cryoproteins (heparin precipitable factor, cryofibrinogen and cryofibrin), and fibronectin. While cryoglobulinemias and plasma-cryoproteinemias are mainly caused by internal diseases, fibronectin may be a physiological substance. Because of skin lesions as purpura, necrosis or cold urticaria the patients rather often consult dermatologists at first. Furthermore arthralgias, kidney diseases, neurologic symptoms and lung involvement can be observed. For diagnosis a accelerated blood sedimentation rate at 37 degrees C and a decelerated at 4 degrees C is helpful. By further investigations underlying internal diseases have to be disclosed. In the therapeutical efforts the treatment of the underlying diseases is most important. Additional plasmapheresis and immunsuppressive treatment may be successful.Publication Types:

Review PMID: 7009493, UI: 81141497

~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Intern Med 1992 Jan;31(1):94-7

Hereditary angioedema complicated with chronic renal failure: report of sibling cases.Nomura H, Tsugawa Y, Koni I, Tofuku Y, Mabuchi H, Takeda R, Sato TSecond Department of Internal Medicine, School of Medicine, Kanazawa University, Japan.Hereditary angioedema (HAE) is known as a deficiency state of C1 inhibitor (C1 INH), an important protease inhibitor protein involved in the complement system. As with other components of the classical pathway of the complement system, a state of its deficiency often causes clinical immunoregulatory disorders. A 45-yr-old brother and a 63-yr-old sister with HAE both developed chronic renal failure, probably due to chronic glomerulonephritis, and required regular hemodialysis. This is, to our knowledge, the first report of sibling cases of HAE associated with chronic renal failure.PMID: 1568052, UI: 92233009 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~If you do wish to unsubscribe then you can click on the following link: <mailto:urticaria-unsubscribeegroups>~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~This list is in the service of those who suffer from Chronic Urticaria (hives). We strive to support and lift each other as a worldwide cyber-family. We share whatever needs to be shared to help one another in our struggle with Chronic Urticria. Any posting that is off the main topic of Chronic Urticaria, we post with a prefix of NCU -. This is done out of respect for those who do not wish to read such postings.