Urticaria Pigmentosa Possibly Reactivated by Contact Allergy.htm

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FromSkin & Allergy News Urticaria Pigmentosa Possibly Reactivated by Contact AllergyDoug Brunk

[skin & Allergy News 29(11):50, 1998. © 1998 International Medical News Group.]

A 31-year-old man had reactivation of urticaria pigmentosa that apparently was associated with a contact allergy to mangoes, reported Lt. A. , MC, USN, of San Diego, Calif., and Lt. Cmdr. P. Schmidt, MC, USNR, of Palo Alto.

Urticaria pigmentosa, a rare disease, is most common among children aged 2-4 years. When disease onset occurs during adulthood, there is increased risk of systemic disease involving the skeletal system or bone marrow, and patients with systemic involvement are at increased risk for malignant transformation (Cutis 62:47-48, 1998).

This patient presented with pruritic red-brown papules and plaques on his abdomen and chest, plus a pink plaque on one wrist. He said that a discrete lesion first appeared on his wrist 2 days after handling mangoes, followed later by the eruptions on the abdomen and chest. The patient said the lesions were identical to those he had had 3 years previously when he was diagnosed with urticaria pigmentosa.

Results of laboratory tests confirmed that the patient did not have systemic disease. Dr. and Dr. Schmidt said that although there are no concrete data available on the probability of malignancy in patients with only cutaneous disease, a complete blood count is a good initial screening tool for this subset of patients.

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