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Re: remodelling

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hi Bobby yes i am in A-fib ( here) and have moved from proximal

to permanent AF, recently started Ameriodone(cordorone )not a lot of

fun and the lungs are not liking it at all.not sure if they will try

electro-Cardioversion they are concerned about remodeling. I am for

my part concerned about not missing the oppertunity for PVA, which

the cardiologist also says is shelf-life-dated.

there are lots of unusual cases but i wonder if you had proximal AF

and always went in and out not in it for 25 years.

What made it possible to convert to to NRS ?which meds were you on ?

I do not want to get into the Atkins debate. hope you can enjoy

these pleasures and stay NSR for you natural life.

Edmonton Canada

> > [i posted this on the LAF phorum a while back so people who read

> > both may want to stop reading here :)]

> >

> > My musings on remodelling (and how much of it is reversible)....

> >

> > There are 3 types of remodelling that can go on,

> > Electrical, contractile and structural.

> > I'm reasonably sure that all 3 are, at least to some extent,

> > reversible.

> >

> > I guess that some structural changes, such as fibrosis are pretty

> hard

> > to recover from but fortunately they are pretty hard to get in the

> > first place, it's not something brief periods of LAF is associated

> > with.

> >

> > As far as contractile remodelling is concerned the recovery seems

to

> > be fairly rapid if your AF doesn't last that long.

> > see

> > http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> cmd=Retrieve & db=PubMed & list_uids=8195510 & dopt=Abstract

> >

> > the nice line from it is

> > " Full recovery of atrial mechanical function, however, is achieved

> > within 24 h in patients with brief[<= 2weeks] atrial fibrillation,

> > within 1 week in patients with moderate-duration [2 to 6 weeks]

> atrial

> > fibrillation and within 1 month in patients with prolonged [> 6

> weeks]

> > atrial fibrillation. "

> >

> > Some electrical remodelling seems to have a quick recovery too,

> taking

> > only a few days to recover even after long [months to years] of

AF.

> >

> > There a several excellent articles to be found in

> > Cardiovascular Research May 2002 Vol 54 No 2

> > (The whole journal is dedicated to AF.)

> >

> > see the table of contents (and abstracts) here...

> > http://www.elsevier.com/gej-ng/10/13/52/99/28/show/toc.htt

> >

> > So perhaps we need to know what remodelling takes place that

> > is hard to recover from? It looks like people with Lone AF (LAF)

and

> > in particular people with Vagally mediated LAF are at the good

end

> of

> > the scale.

> >

> > Just as, in some cases, AF begets AF I'm sure that it's true that

> NSR

> > begets NSR for some individuals.

> > --

> > D

>

>

>

>

>

>

>

>

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I was diagnosed several years ago, but at that time, my heart rhythm was

as I had always known it, even as a child. When I was diagnosed, I was

in afib all the time. There was no getting out without a cardioversion.

After my first, I went back to afib in a couple of days. The next was

with meds, and I lasted weeks. The meds were increased (flecainide) and

here I am in normal rhythm.

Is amiodarone your only choice? I know your system is different in

Canada.

Re: remodelling

hi Bobby yes i am in A-fib ( here) and have moved from proximal

to permanent AF, recently started Ameriodone(cordorone )not a lot of

fun and the lungs are not liking it at all.not sure if they will try

electro-Cardioversion they are concerned about remodeling. I am for

my part concerned about not missing the oppertunity for PVA, which

the cardiologist also says is shelf-life-dated.

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  • 1 month later...
Guest guest

In a message dated 3/28/2003 9:56:39 AM Pacific Standard Time,

martin.pile1@... writes:

<< In past posts the term " the heart remodells itself " what is the

outcome if this happens and how long does it take and under what

circumstances.

Any input would be most welcome. >>

,

I was worried about remodeling since I have had afib for about twenty years,

but it hasn't happened. I guess it can take longer than twenty years! I

have now been in sinus continuously for the past ten and a half months except

for fifteen minutes of afib on last Dec. 1. During my afib career I have had

many episodes of four, five, six, eight, and ten days, during which I was

sure I would stay in permanent afib, but it hasn't happened yet. I suspect

that a number of conditions and circumstances must be present to allow

permanent afib to occur.

Since I have an older brother who was in permanent afib by the time he was my

current age, it's probable that it would have happened to me, also, if I had

not lived a different lifestyle. His doctor tells my brother that his heart

has been remodeled, and that ablation or surgery will not help. My brother

believes, and I agree, that I have been able to overcome an obvious genetic

tendency toward afib in our family because I began taking medication

(Atenolol) six years after afib started, because I have never drunk alcohol

or smoked excessively as my brother did, and because I stopped my excessive

coffee habit when I realized it was contributing to my problems. I also

modified my food/eating habits and restructured activities, but it wasn't

until I eliminated dairy products from my life that I began to enjoy this

long period of sinus. I think that lifestyle changes and medication can help

to prevent remodeling in some individuals, but in others remodeling may be

inevitable if certain conditions are present. The important thing to

remember is that we are all different, so it may be impossible to say whether

and when remodeling will occur except by individual analysis.

in sinus in Seattle (Ten and a half months as of yesterday)

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  • 2 weeks later...
Guest guest

Does remodeling make exclude one from becoming an ablation candidate?

--

>

> Reply-To: AFIBsupport

> Date: Fri, 11 Apr 2003 16:40:56 -0000

> To: AFIBsupport

> Subject: Re: remodelling

>

>

>>

>>

>>

>> Remodeling can take place in a few days although it often takes

>> longer.Remodelign is a combination of proceses combining the change

> in the

>> electrical inpulses and phisical changes in the tissue (substrate )

>> In my case I had intermittent events for years culmanating in a two

> week

>> illness that seems to have put me in permanent AF.

>>

>

>

> Before every newbie freaks out, let me add that there are innumerable

> people in here who have had afib for a few days or longer and have

> not gone into permanent afib. Also, " un-remodeling " can take place

> as one stays in normal sinus rhythm.

>

>

>

>

>

> Web Page - http://groups.yahoo.com/group/AFIBsupport

> FAQ - http://groups.yahoo.com/group/AFIBsupport/files/Administrative/faq.htm

> For more information: http://www.dialsolutions.com/af

> Unsubscribe: AFIBsupport-unsubscribe

> List owner: AFIBsupport-owner

> For help on how to use the group, including how to drive it via email,

> send a blank email to AFIBsupport-help

>

> Nothing in this message should be considered as medical advice, or should be

> acted upon without consultation with one's physician.

>

>

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  • 2 weeks later...
Guest guest

>

>

>In past posts the term " the heart remodells itself " what is the

>outcome if this happens and how long does it take and under what

>circumstances.

>

I forgot to mention that I don't know how long it takes. It probably

varies per individual. In experimental studies researchers have been

able to push a goat's heart into Chronic A-Fib in a week or two, which

is really scary.

" A-Fib begets A-Fib. " The more you are in A-Fib, the greater will be

the tendency for your heart to remodel itself.

A-FibFriendSteve

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