Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 This is nice . I did not know incontenance can come from NF2. I have had it for 8+ years, and has gotten worse over time. I thought is was from having a baby!! Do you have anymore information on this?? Thanks...Carol Chartrand wrote: > I'm putting together some " quick facts " to supplement an article I'm > writing. Your criticism and input is needed to judge my " facts. " > > Neurofibromatosis type 2 (NF2) - Quick facts > - NF2 causes benign tumours to form on both vestibular nerve complexes, > other cranial nerves, the spinal cord, and occasionally other parts of the > body. Cataracts are also very common. > - The results of NF2 are usually deafness, facial paralysis and loss of > balance. > - Other results may be limb weakness or paralysis, bilateral facial > paralysis, blindness, swallowing problems, pain, incontinence, and ??? > - NF2 occurs in every 1 in 40 000 people. > - NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to > recessive) genetic defect on chromosome 22. > - The defect is thought to interfere with the gene that produces the protein > Merlin, which acts as a tumour suppressing protein. > - A person with NF2 has a 50-50 chance of passing th disease on to their > children. > - Half of all people with NF2 did not inherit the disease, and are > spontaneous mutations. > - There is no effective treatment or cure for NF2, other than removing > tumours, or irradiating them. > > > -- > " In Man's pursuit of Salvation, his committment > to his Science or his Religion may be the only > thing keeping him from it. " > > Http://www.westerncanada.com/~jchartra Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 This is nice . I did not know incontenance can come from NF2. I have had it for 8+ years, and has gotten worse over time. I thought is was from having a baby!! Do you have anymore information on this?? Thanks...Carol Chartrand wrote: > I'm putting together some " quick facts " to supplement an article I'm > writing. Your criticism and input is needed to judge my " facts. " > > Neurofibromatosis type 2 (NF2) - Quick facts > - NF2 causes benign tumours to form on both vestibular nerve complexes, > other cranial nerves, the spinal cord, and occasionally other parts of the > body. Cataracts are also very common. > - The results of NF2 are usually deafness, facial paralysis and loss of > balance. > - Other results may be limb weakness or paralysis, bilateral facial > paralysis, blindness, swallowing problems, pain, incontinence, and ??? > - NF2 occurs in every 1 in 40 000 people. > - NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to > recessive) genetic defect on chromosome 22. > - The defect is thought to interfere with the gene that produces the protein > Merlin, which acts as a tumour suppressing protein. > - A person with NF2 has a 50-50 chance of passing th disease on to their > children. > - Half of all people with NF2 did not inherit the disease, and are > spontaneous mutations. > - There is no effective treatment or cure for NF2, other than removing > tumours, or irradiating them. > > > -- > " In Man's pursuit of Salvation, his committment > to his Science or his Religion may be the only > thing keeping him from it. " > > Http://www.westerncanada.com/~jchartra Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 This is nice . I did not know incontenance can come from NF2. I have had it for 8+ years, and has gotten worse over time. I thought is was from having a baby!! Do you have anymore information on this?? Thanks...Carol Chartrand wrote: > I'm putting together some " quick facts " to supplement an article I'm > writing. Your criticism and input is needed to judge my " facts. " > > Neurofibromatosis type 2 (NF2) - Quick facts > - NF2 causes benign tumours to form on both vestibular nerve complexes, > other cranial nerves, the spinal cord, and occasionally other parts of the > body. Cataracts are also very common. > - The results of NF2 are usually deafness, facial paralysis and loss of > balance. > - Other results may be limb weakness or paralysis, bilateral facial > paralysis, blindness, swallowing problems, pain, incontinence, and ??? > - NF2 occurs in every 1 in 40 000 people. > - NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to > recessive) genetic defect on chromosome 22. > - The defect is thought to interfere with the gene that produces the protein > Merlin, which acts as a tumour suppressing protein. > - A person with NF2 has a 50-50 chance of passing th disease on to their > children. > - Half of all people with NF2 did not inherit the disease, and are > spontaneous mutations. > - There is no effective treatment or cure for NF2, other than removing > tumours, or irradiating them. > > > -- > " In Man's pursuit of Salvation, his committment > to his Science or his Religion may be the only > thing keeping him from it. " > > Http://www.westerncanada.com/~jchartra Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 Instead of " cataracts " , I would specify " subcapsular lens opacitities, a specific type of cataract " . See below--my comment in () Marie Help quickly needed >I'm putting together some " quick facts " to supplement an article I'm >writing. Your criticism and input is needed to judge my " facts. " > >Neurofibromatosis type 2 (NF2) - Quick facts >- NF2 causes benign tumours to form on both vestibular nerve complexes, >other cranial nerves, the spinal cord, and occasionally other parts of the >body. Cataracts are also very common. >- The results of NF2 are usually(I would change the word usually to often) deafness, facial paralysis and loss of >balance. (>- Other results may be limb weakness or paralysis, bilateral facial >paralysis, blindness, swallowing problems, pain, incontinence, and ??? >- NF2 occurs in every 1 in 40 000 people. >- NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to >recessive) genetic defect on chromosome 22. >- The defect is thought to interfere with the gene that produces the protein >Merlin, which acts as a tumour suppressing protein. >- A person with NF2 has a 50-50 chance of passing th disease on to their >children. >- Half of all people with NF2 did not inherit the disease, and are >spontaneous mutations. >- There is no effective treatment or cure for NF2, other than removing >tumours, or irradiating them. >*(I would add the part that even if a person is spontaneous, THEIR children face the 50/50 chance--recently met a person who thought their was no danger of their children having the disease because they were sporadic)> >-- > " In Man's pursuit of Salvation, his committment >to his Science or his Religion may be the only >thing keeping him from it. " > >Http://www.westerncanada.com/~jchartra > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 Instead of " cataracts " , I would specify " subcapsular lens opacitities, a specific type of cataract " . See below--my comment in () Marie Help quickly needed >I'm putting together some " quick facts " to supplement an article I'm >writing. Your criticism and input is needed to judge my " facts. " > >Neurofibromatosis type 2 (NF2) - Quick facts >- NF2 causes benign tumours to form on both vestibular nerve complexes, >other cranial nerves, the spinal cord, and occasionally other parts of the >body. Cataracts are also very common. >- The results of NF2 are usually(I would change the word usually to often) deafness, facial paralysis and loss of >balance. (>- Other results may be limb weakness or paralysis, bilateral facial >paralysis, blindness, swallowing problems, pain, incontinence, and ??? >- NF2 occurs in every 1 in 40 000 people. >- NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to >recessive) genetic defect on chromosome 22. >- The defect is thought to interfere with the gene that produces the protein >Merlin, which acts as a tumour suppressing protein. >- A person with NF2 has a 50-50 chance of passing th disease on to their >children. >- Half of all people with NF2 did not inherit the disease, and are >spontaneous mutations. >- There is no effective treatment or cure for NF2, other than removing >tumours, or irradiating them. >*(I would add the part that even if a person is spontaneous, THEIR children face the 50/50 chance--recently met a person who thought their was no danger of their children having the disease because they were sporadic)> >-- > " In Man's pursuit of Salvation, his committment >to his Science or his Religion may be the only >thing keeping him from it. " > >Http://www.westerncanada.com/~jchartra > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 Instead of " cataracts " , I would specify " subcapsular lens opacitities, a specific type of cataract " . See below--my comment in () Marie Help quickly needed >I'm putting together some " quick facts " to supplement an article I'm >writing. Your criticism and input is needed to judge my " facts. " > >Neurofibromatosis type 2 (NF2) - Quick facts >- NF2 causes benign tumours to form on both vestibular nerve complexes, >other cranial nerves, the spinal cord, and occasionally other parts of the >body. Cataracts are also very common. >- The results of NF2 are usually(I would change the word usually to often) deafness, facial paralysis and loss of >balance. (>- Other results may be limb weakness or paralysis, bilateral facial >paralysis, blindness, swallowing problems, pain, incontinence, and ??? >- NF2 occurs in every 1 in 40 000 people. >- NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to >recessive) genetic defect on chromosome 22. >- The defect is thought to interfere with the gene that produces the protein >Merlin, which acts as a tumour suppressing protein. >- A person with NF2 has a 50-50 chance of passing th disease on to their >children. >- Half of all people with NF2 did not inherit the disease, and are >spontaneous mutations. >- There is no effective treatment or cure for NF2, other than removing >tumours, or irradiating them. >*(I would add the part that even if a person is spontaneous, THEIR children face the 50/50 chance--recently met a person who thought their was no danger of their children having the disease because they were sporadic)> >-- > " In Man's pursuit of Salvation, his committment >to his Science or his Religion may be the only >thing keeping him from it. " > >Http://www.westerncanada.com/~jchartra > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 Hi - I have read and been told three different statistics for percentage of NF2 people. I have read one in thirty thousand. Have read one in forty thousand Was told by my doctors and the genealogy clinic doctors I am seeing - one in fifty thousand. Take your pick huh? Also, on my last brain surgery I had 3 tumors removed. The most blessed part of that for me even today - I still rant and rave about it - I BREATHE easier. In fact, I just saw my NF2 doctor yesterday. He is an OTO doctor. I reminded him of just that - I breathe easier. Hope this helps. It is not meant to confuse you - the statistics. It is just what has come my way. Of course, my doctors stand behind the one in fifty thousand. They are from the University of Iowa Hospitals and Clinics in Iowa City, Iowa - U S A. I am new on the crew - have to remember to put in U S A. Jane Help quickly needed >I'm putting together some " quick facts " to supplement an article I'm >writing. Your criticism and input is needed to judge my " facts. " > >Neurofibromatosis type 2 (NF2) - Quick facts >- NF2 causes benign tumours to form on both vestibular nerve complexes, >other cranial nerves, the spinal cord, and occasionally other parts of the >body. Cataracts are also very common. >- The results of NF2 are usually deafness, facial paralysis and loss of >balance. >- Other results may be limb weakness or paralysis, bilateral facial >paralysis, blindness, swallowing problems, pain, incontinence, and ??? >- NF2 occurs in every 1 in 40 000 people. >- NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to >recessive) genetic defect on chromosome 22. >- The defect is thought to interfere with the gene that produces the protein >Merlin, which acts as a tumour suppressing protein. >- A person with NF2 has a 50-50 chance of passing th disease on to their >children. >- Half of all people with NF2 did not inherit the disease, and are >spontaneous mutations. >- There is no effective treatment or cure for NF2, other than removing >tumours, or irradiating them. > > > >-- > " In Man's pursuit of Salvation, his committment >to his Science or his Religion may be the only >thing keeping him from it. " > >Http://www.westerncanada.com/~jchartra > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 Hi - I have read and been told three different statistics for percentage of NF2 people. I have read one in thirty thousand. Have read one in forty thousand Was told by my doctors and the genealogy clinic doctors I am seeing - one in fifty thousand. Take your pick huh? Also, on my last brain surgery I had 3 tumors removed. The most blessed part of that for me even today - I still rant and rave about it - I BREATHE easier. In fact, I just saw my NF2 doctor yesterday. He is an OTO doctor. I reminded him of just that - I breathe easier. Hope this helps. It is not meant to confuse you - the statistics. It is just what has come my way. Of course, my doctors stand behind the one in fifty thousand. They are from the University of Iowa Hospitals and Clinics in Iowa City, Iowa - U S A. I am new on the crew - have to remember to put in U S A. Jane Help quickly needed >I'm putting together some " quick facts " to supplement an article I'm >writing. Your criticism and input is needed to judge my " facts. " > >Neurofibromatosis type 2 (NF2) - Quick facts >- NF2 causes benign tumours to form on both vestibular nerve complexes, >other cranial nerves, the spinal cord, and occasionally other parts of the >body. Cataracts are also very common. >- The results of NF2 are usually deafness, facial paralysis and loss of >balance. >- Other results may be limb weakness or paralysis, bilateral facial >paralysis, blindness, swallowing problems, pain, incontinence, and ??? >- NF2 occurs in every 1 in 40 000 people. >- NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to >recessive) genetic defect on chromosome 22. >- The defect is thought to interfere with the gene that produces the protein >Merlin, which acts as a tumour suppressing protein. >- A person with NF2 has a 50-50 chance of passing th disease on to their >children. >- Half of all people with NF2 did not inherit the disease, and are >spontaneous mutations. >- There is no effective treatment or cure for NF2, other than removing >tumours, or irradiating them. > > > >-- > " In Man's pursuit of Salvation, his committment >to his Science or his Religion may be the only >thing keeping him from it. " > >Http://www.westerncanada.com/~jchartra > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2000 Report Share Posted October 5, 2000 Hi - I have read and been told three different statistics for percentage of NF2 people. I have read one in thirty thousand. Have read one in forty thousand Was told by my doctors and the genealogy clinic doctors I am seeing - one in fifty thousand. Take your pick huh? Also, on my last brain surgery I had 3 tumors removed. The most blessed part of that for me even today - I still rant and rave about it - I BREATHE easier. In fact, I just saw my NF2 doctor yesterday. He is an OTO doctor. I reminded him of just that - I breathe easier. Hope this helps. It is not meant to confuse you - the statistics. It is just what has come my way. Of course, my doctors stand behind the one in fifty thousand. They are from the University of Iowa Hospitals and Clinics in Iowa City, Iowa - U S A. I am new on the crew - have to remember to put in U S A. Jane Help quickly needed >I'm putting together some " quick facts " to supplement an article I'm >writing. Your criticism and input is needed to judge my " facts. " > >Neurofibromatosis type 2 (NF2) - Quick facts >- NF2 causes benign tumours to form on both vestibular nerve complexes, >other cranial nerves, the spinal cord, and occasionally other parts of the >body. Cataracts are also very common. >- The results of NF2 are usually deafness, facial paralysis and loss of >balance. >- Other results may be limb weakness or paralysis, bilateral facial >paralysis, blindness, swallowing problems, pain, incontinence, and ??? >- NF2 occurs in every 1 in 40 000 people. >- NF2 is an autosomal (as opposed to sex-linked), dominant (as opposed to >recessive) genetic defect on chromosome 22. >- The defect is thought to interfere with the gene that produces the protein >Merlin, which acts as a tumour suppressing protein. >- A person with NF2 has a 50-50 chance of passing th disease on to their >children. >- Half of all people with NF2 did not inherit the disease, and are >spontaneous mutations. >- There is no effective treatment or cure for NF2, other than removing >tumours, or irradiating them. > > > >-- > " In Man's pursuit of Salvation, his committment >to his Science or his Religion may be the only >thing keeping him from it. " > >Http://www.westerncanada.com/~jchartra > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I have read that if you have NF2 you have a 99% chance of passing it on to half your children. Anita Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I have read that if you have NF2 you have a 99% chance of passing it on to half your children. Anita Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 In a message dated 10/6/00 2:33:17 PM Eastern Daylight Time, mcdrew@... writes: << you have a child and that DEFI NITELY does not have NF2, then HIS children will NOT get NF2 >> Unless his/her children are spontaneous cases.. But what Marie's point is (and this what I've been told) NF2 doesn't skip a generation.. If you don't give it to your siblings, you don't have any effect on their kids, they have just as much of a chance of getting it spontaneously as everyone else Pete Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 mcdrew@... writes: << The correct thing is: If you have NF2, each of your children have an 50% chance of inheriting it. This is true even if you are a spontaneous case. However if you have NF2, you have a child and that DEFI NITELY does not have NF2, then HIS children will NOT get NF2. Correct me if I am wrong, but I am pretty sure this is accurate. Marie >> ****************************************************************************** I think Marie is right on. To complicate matters a bit though, as I've posted before, some of us may be what's called " mosaic " for NF-2--i.e., not all of the our cells have the defective gene. (That's probably the case with me because my NF-2 is relatively mild.) The luck of the draw could include the sperm or egg cell. Consequently, the chances someone with mosaic NF-2 would pass the disease on to an offspring are less than the usual 50 percent probability. In a letter, Dr. Dilys Parry of the National Institutes of Health discussed " mosaic " NF-2: " ... the term " mosaic " means a mixture of two types of cells. In the few people who have been shown to be mosaic for NF-2, probably 10% or so of their cells have one mutated NF-2 gene and one normal NF-2 gene, while the rest of the cells carry two normal copies of this gene. Mosaicism results when an NF-2 mutation occurs early in embryonic development, rather than being inherited through an egg or sperm from a parent. " Steve Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 In a message dated 10/6/00 3:40:36 PM Eastern Daylight Time, amazon40@... writes: << Hi Crew,Just thought i would pass on what we were told about Nf2.My son has NF2,my father has NF1.I have absolutely nothing.I was also told it doesn't skip a generation.Figure that one out.My son was told it is a 50% chance of his children having this lovely disease.It's bad when a 20 yr old man is considering a vasectomy. Pam Lakeman >> Most likely he was a spontaneous mutation and there wasn't any connection between your father and him.. I think (I'm guessing here admittedly) if you have NF1 you can't give your kids NF2 or vice versa, I think it stays the same. I could be wrong tho Pete Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I was told that my kids have a 50% chance of having it and my grandchildren 25%. Carol schweickerta@... wrote: > I have read that if you have NF2 you have a 99% chance of passing it on to > half your children. > > Anita Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I was told that my kids have a 50% chance of having it and my grandchildren 25%. Carol schweickerta@... wrote: > I have read that if you have NF2 you have a 99% chance of passing it on to > half your children. > > Anita Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 The correct thing is: If you have NF2, each of your children have an 50% chance of inheriting it. This is true even if you are a spontaneous case. However if you have NF2, you have a child and that DEFI NITELY does not have NF2, then HIS children will NOT get NF2. Correct me if I am wrong, but I am pretty sure this is accurate. Marie Re: Help quickly needed >I have read that if you have NF2 you have a 99% chance of passing it on to >half your children. > >Anita > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I think that is incorrect. marie Re: Help quickly needed >I was told that my kids have a 50% chance of having it and my grandchildren >25%. > >Carol > >schweickerta@... wrote: > >> I have read that if you have NF2 you have a 99% chance of passing it on to >> half your children. >> >> Anita > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 You're right, Marie. It is incorrect. If does NOT skip generations. 50/50 chance of passing on to kids, NO chance of passing it on to grandkids if the kids did not get it. --- Marie Drew wrote: > I think that is incorrect. marie > Re: Help quickly needed > > > >I was told that my kids have a 50% chance of having > it and my grandchildren > >25%. > > > >Carol > > > >schweickerta@... wrote: > > > >> I have read that if you have NF2 you have a 99% > chance of passing it on > to > >> half your children. > >> > >> Anita > > > > > > > > > > > > > > __________________________________________________ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 Hi Crew,Just thought i would pass on what we were told about Nf2.My son has NF2,my father has NF1.I have absolutely nothing.I was also told it doesn't skip a generation.Figure that one out.My son was told it is a 50% chance of his children having this lovely disease.It's bad when a 20 yr old man is considering a vasectomy. Pam Lakeman Re: Help quickly needed > > > > > > >I was told that my kids have a 50% chance of having > > it and my grandchildren > > >25%. > > > > > >Carol > > > > > >schweickerta@... wrote: > > > > > >> I have read that if you have NF2 you have a 99% > > chance of passing it on > > to > > >> half your children. > > >> > > >> Anita > > > > > > > > > > > > > > > > > > > > > > > > > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 Wow Steve, that is the first I had heard those stats. Now, how do they decide if you are " mosaic " --my case is more severe than yours, but certainly not as agressive as some. I had thought I had mosaic because I was late onset, and had only bi-laterals. Thinking my kids were then less likely to inherit. However, Hawkins has exactly the same pattern as me, and she has recently found 3 of her 5 have inherited~! Still interesting, thanks, Marie Re: Help quickly needed >mcdrew@... writes: > ><< The correct thing is: If you have NF2, each of your children have an 50% > chance of inheriting it. This is true even if you are a spontaneous case. > However if you have NF2, you have a child and that DEFI NITELY does not have > NF2, then HIS children will NOT get NF2. Correct me if I am wrong, but I am > pretty sure this is accurate. > Marie >> > > >*************************************************************************** *** > >I think Marie is right on. > >To complicate matters a bit though, as I've posted before, some of us may be >what's called " mosaic " for NF-2--i.e., not all of the our cells have the >defective gene. (That's probably the case with me because my NF-2 is >relatively mild.) The luck of the draw could include the sperm or egg cell. >Consequently, the chances someone with mosaic NF-2 would pass the disease on >to an offspring are less than the usual 50 percent probability. > >In a letter, Dr. Dilys Parry of the National Institutes of Health discussed > " mosaic " NF-2: > > " ... the term " mosaic " means a mixture of two types of > cells. In the few people who have been shown to be mosaic > for NF-2, probably 10% or so of their cells have one mutated > NF-2 gene and one normal NF-2 gene, while the rest of the > cells carry two normal copies of this gene. Mosaicism > results when an NF-2 mutation occurs early in embryonic > development, rather than being inherited through an egg or > sperm from a parent. " > > > > Steve > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 That is what I heard too Marie. -Lori Re: Help quickly needed > > > >I have read that if you have NF2 you have a 99% chance of passing it on to > >half your children. > > > >Anita > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I believe Pete is right, the NF 1 gene is the 16th, I believe while NF2 is the 22nd. Apples and oranges, BUT there are a lot of people out there that have both. I would like to know if Pam lives in a state of agriculture or industry?? Re: Help quickly needed > In a message dated 10/6/00 3:40:36 PM Eastern Daylight Time, > amazon40@... writes: > > << Hi Crew,Just thought i would pass on what we were told about Nf2.My son has > NF2,my father has NF1.I have absolutely nothing.I was also told it doesn't > skip a generation.Figure that one out.My son was told it is a 50% chance of > his children having this lovely disease.It's bad when a 20 yr old man is > considering a vasectomy. Pam Lakeman >> > > Most likely he was a spontaneous mutation and there wasn't any connection > between your father and him.. I think (I'm guessing here admittedly) if you > have NF1 you can't give your kids NF2 or vice versa, I think it stays the > same. I could be wrong tho > > Pete > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 Pete, From what I've heard doctors say through the years if you have NF1 and your child inherits, it WILL inherit NF1. Coversely, if you have NF2 and the child inherist it will be NF2 that is inherited. I've heard doctors say if you have one type of NF that is what is inherited. Just repeating what I've heard the docs say. K. Re: Help quickly needed > In a message dated 10/6/00 3:40:36 PM Eastern Daylight Time, > amazon40@... writes: > > << Hi Crew,Just thought i would pass on what we were told about Nf2.My son has > NF2,my father has NF1.I have absolutely nothing.I was also told it doesn't > skip a generation.Figure that one out.My son was told it is a 50% chance of > his children having this lovely disease.It's bad when a 20 yr old man is > considering a vasectomy. Pam Lakeman >> > > Most likely he was a spontaneous mutation and there wasn't any connection > between your father and him.. I think (I'm guessing here admittedly) if you > have NF1 you can't give your kids NF2 or vice versa, I think it stays the > same. I could be wrong tho > > Pete > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2000 Report Share Posted October 6, 2000 I agree - this is exactly what I have been told by the genetic doctors working with me. Jane Re: Help quickly needed >Yes I agree with you Pete. From what I have understood from my readings and >my Geneticists your words are so. > >ine > Re: Help quickly needed > > >> In a message dated 10/6/00 2:33:17 PM Eastern Daylight Time, mcdrew@... >> writes: >> >> << you have a child and that DEFI NITELY does not have >> NF2, then HIS children will NOT get NF2 >> >> >> >> Unless his/her children are spontaneous cases.. >> But what Marie's point is (and this what I've been told) NF2 doesn't skip >a >> generation.. If you don't give it to your siblings, you don't have any >effect >> on their kids, they have just as much of a chance of getting it >spontaneously >> as everyone else >> >> Pete >> >> >> >> > > > > Quote Link to comment Share on other sites More sharing options...
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