Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 I think this is the link to it in case anyone wants to print it out? [uS] http://www.kingpharm.com/products/product_document.cfm?brand_name=Cytomel & produc\ t_specific_name= & document_type_code=PI ]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 I think this is the link to it in case anyone wants to print it out? [uS] http://www.kingpharm.com/products/product_document.cfm?brand_name=Cytomel & produc\ t_specific_name= & document_type_code=PI ]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > >]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf This is interesting, from that link " Following oral administration, about 95% of the dose of liothyronine is absorbed from the gastrointestinal tract in four hours. Liothyronine, not firmly bound to serum protein, is readily available to body tissues. Its biologic half-life is about 2 1/2 days. Liothyronine has a rapid cut-off of activity which permits quick dosage adjustment and facilitates control of the effects of overdosage should they occur. " That's a much longer half life than I had realised, I thought it was hours rather than days. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > >]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf This is interesting, from that link " Following oral administration, about 95% of the dose of liothyronine is absorbed from the gastrointestinal tract in four hours. Liothyronine, not firmly bound to serum protein, is readily available to body tissues. Its biologic half-life is about 2 1/2 days. Liothyronine has a rapid cut-off of activity which permits quick dosage adjustment and facilitates control of the effects of overdosage should they occur. " That's a much longer half life than I had realised, I thought it was hours rather than days. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > >]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf > And again from that " Severe and prolonged hypothyroidism can lead to a decreased level of adrenocortical activity commensurate with the lowered metabolic state. When thyroid replacement therapy is administered, the metabolism increases at a greater rate than adrenocortical activity. This can precipitate adrenocortical insufficience. Therefore, in severe and prolonged hypothyroidism, supplemental adrenocortical steroids may be necessary. " Why are the Drs so reluctant to believe that when it's on the drug packet inserts!! Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > >]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf > And again from that " Severe and prolonged hypothyroidism can lead to a decreased level of adrenocortical activity commensurate with the lowered metabolic state. When thyroid replacement therapy is administered, the metabolism increases at a greater rate than adrenocortical activity. This can precipitate adrenocortical insufficience. Therefore, in severe and prolonged hypothyroidism, supplemental adrenocortical steroids may be necessary. " Why are the Drs so reluctant to believe that when it's on the drug packet inserts!! Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > >]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf > And again " Optimum dosage is usually determined by the patient's clinical response. Confirmatory tests include: RadioActive Iodine T3 Resin Uptake, 131I-T3 Red Cell Uptake, BMR, and the Achilles Tendon Reflex test. Comparatively small doses (as little as 5 µg daily) may be fully effective in some cases; however, in other instances, a satisfactory clinical response may not be achieved until recommended dosage levels have been exceeded. Daily doses up to 150 µg are sometimes well tolerated and may be optimal in a few resistant patients. " The last sentence of that one is useful for anyone who's Dr won't let them increase dose. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > >]canada] http://www.kingpharm.ca/downloads/Cytomel_PI-Fre-Eng.pdf > And again " Optimum dosage is usually determined by the patient's clinical response. Confirmatory tests include: RadioActive Iodine T3 Resin Uptake, 131I-T3 Red Cell Uptake, BMR, and the Achilles Tendon Reflex test. Comparatively small doses (as little as 5 µg daily) may be fully effective in some cases; however, in other instances, a satisfactory clinical response may not be achieved until recommended dosage levels have been exceeded. Daily doses up to 150 µg are sometimes well tolerated and may be optimal in a few resistant patients. " The last sentence of that one is useful for anyone who's Dr won't let them increase dose. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 " " That's a much longer half life than I had realised, I thought it was hours rather than days. " " Yes unfortunately when you read about the half life o fT3 you wil get any number of DIFFERNT opinions. Even from research sites. I honestly believe the half life depends on how much you NEED such as I think it lasts longer in thebody when you have full saturation and also whenhavign a easy day. I think it is used much faster whne we are veyr hypothyroid or when we have very active days. I knwo I have played ht " stress dosing " extra on my mroe difficult days at work and it seems to really nbe heloful with my fatigue. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 " " That's a much longer half life than I had realised, I thought it was hours rather than days. " " Yes unfortunately when you read about the half life o fT3 you wil get any number of DIFFERNT opinions. Even from research sites. I honestly believe the half life depends on how much you NEED such as I think it lasts longer in thebody when you have full saturation and also whenhavign a easy day. I think it is used much faster whne we are veyr hypothyroid or when we have very active days. I knwo I have played ht " stress dosing " extra on my mroe difficult days at work and it seems to really nbe heloful with my fatigue. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 GOOD QUESTION! I have often found it is jst new concepts that take FOREVER to be indoctrinated into a doctor's mindset, but Cytomel has been around for MANY years when wil it ever gain accceptance as a valid hypothyroidism treatment? Probabyl nto until doctors realize patients CAN be relied upon to multi-dose and and that they need to LEARN mroe than what thye are taught in med school once in practice. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 GOOD QUESTION! I have often found it is jst new concepts that take FOREVER to be indoctrinated into a doctor's mindset, but Cytomel has been around for MANY years when wil it ever gain accceptance as a valid hypothyroidism treatment? Probabyl nto until doctors realize patients CAN be relied upon to multi-dose and and that they need to LEARN mroe than what thye are taught in med school once in practice. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > I think it lasts longer in thebody when you have full saturation and also whenhavign a easy day. I think it is used much faster whne we are veyr hypothyroid or when we have very active days. I knwo I have played ht " stress dosing " extra on my mroe difficult days at work and it seems to really nbe heloful with my fatigue. That makes sense to me, I've been taking an extra grain or two of Armour late afternoon if I feel I need it for years. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 > I think it lasts longer in thebody when you have full saturation and also whenhavign a easy day. I think it is used much faster whne we are veyr hypothyroid or when we have very active days. I knwo I have played ht " stress dosing " extra on my mroe difficult days at work and it seems to really nbe heloful with my fatigue. That makes sense to me, I've been taking an extra grain or two of Armour late afternoon if I feel I need it for years. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 >Probabyl nto until doctors realize patients >CAN be relied upon to multi-dose and and that they need to LEARN mroe >than what thye are taught in med school once in practice. Yes, plus most Drs seem frightened of patients knowing what is happening in them, and Thyroid is one of those subjects where being an educated patient helps. Dr D-P that I started with was Hypo himself, that's what started him along that specialty. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 >Probabyl nto until doctors realize patients >CAN be relied upon to multi-dose and and that they need to LEARN mroe >than what thye are taught in med school once in practice. Yes, plus most Drs seem frightened of patients knowing what is happening in them, and Thyroid is one of those subjects where being an educated patient helps. Dr D-P that I started with was Hypo himself, that's what started him along that specialty. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 I have actually wondered many times if this fluctuating need for thyroid might not be why many people have troubel feeling well on thyroid meds. With Armour, or other natural thyroid meds you have conversion of T4 when you need extra T3, but with T3 only your T4 levels end up in the dirt so taking a bit extra for harder days makes good sense. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 I have actually wondered many times if this fluctuating need for thyroid might not be why many people have troubel feeling well on thyroid meds. With Armour, or other natural thyroid meds you have conversion of T4 when you need extra T3, but with T3 only your T4 levels end up in the dirt so taking a bit extra for harder days makes good sense. -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 Yes most the better thyroid or thyroid/adrenal doctors have dealt with it ona real personal basis. I think it gies them a RARE INSIGHT into our issues! LOL -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 >With Armour, or other natural thyroid meds you have conversion of T4 >when you need extra T3, but with T3 only your T4 levels end up in the >dirt so taking a bit extra for harder days makes good sense. Which is why I am feeling the fluctuation. As far as I can tell I have no significant conversion and hence am doseing on the T3 only. I experimented with an extra grain at bed time over the weekend and it was a failure for me. I slept OK but ended up feeling very spacey all day the following day, tried it for 2 nights and decided it wasn't for me. My stock of T3 arrived yesterday and I will probably try the change on Friday so if I feel out of sorts it's over the weekend again. I'll let you all know how it goes for me. Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 Good luck Nick! -- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 >Good luck Nick! Thanks Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 >Good luck Nick! Thanks Nick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 this is interesting..as some days Ill notice constipation, or more tired, but always thought that "Im at the right t3 dose" ,so I assume its iron..or adrenal. Subject: Re: Re: Cytomel Insert - Helpful for getting t3 prescribed?To: RT3_T3 Date: Wednesday, May 6, 2009, 4:21 AM I have actually wondered many times if this fluctuating need for thyroid might not be why many people have troubel feeling well on thyroid meds. With Armour, or other natural thyroid meds you have conversion of T4 when you need extra T3, but with T3 only your T4 levels end up in the dirt so taking a bit extra for harder days makes good sense.-- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2009 Report Share Posted May 6, 2009 this is interesting..as some days Ill notice constipation, or more tired, but always thought that "Im at the right t3 dose" ,so I assume its iron..or adrenal. Subject: Re: Re: Cytomel Insert - Helpful for getting t3 prescribed?To: RT3_T3 Date: Wednesday, May 6, 2009, 4:21 AM I have actually wondered many times if this fluctuating need for thyroid might not be why many people have troubel feeling well on thyroid meds. With Armour, or other natural thyroid meds you have conversion of T4 when you need extra T3, but with T3 only your T4 levels end up in the dirt so taking a bit extra for harder days makes good sense.-- Artistic Grooming- Hurricane WV http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ http://health.groups.yahoo.com/group/RT3_T3/ http://groups.yahoo.com/group/HypoPets/------------------------------------ Quote Link to comment Share on other sites More sharing options...
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