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> In the reverse way, that is what I was hoping to do. Get tested just

> after a blood donation, then again 2 months later just before the next

> one.

I got ferritin rechecked after a donation and it went up. I think maybe you have

to give it awhile to balance itself.

Dorothy

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How much blood do they take for a donation? Wouldn't that be enough

to affect levels in someone that is low?

Elyse

>

>> In the reverse way, that is what I was hoping to do. Get tested just

>> after a blood donation, then again 2 months later just before the next

>> one.

>

> I got ferritin rechecked after a donation and it went up. I think maybe you

> have to give it awhile to balance itself.

>

> Dorothy

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--- At 09:08 PM 3/26/2009, sol wrote:

>

>... I also know of a person who does fine with desiccated thyroid at ferritin

of 16-20. The question should be why doesn't everyone?

>

>I can't help but believe there is more going on with iron and thyroid than just

ferritin being too low. Just because no one seems to know how to get low

ferritin people to " tolerate " their thyroid meds with low ferritin does not at

all mean there isn't some other reason which is being overlooked. Otherwise no

one at all could take thyroid meds with very low ferritin, but people DO, and

successfully too. ...

High copper, or low copper -- both block iron absorption.

Bill

COPPER TOXICITY SYNDROME

http://drlwilson.com/Articles/copper_toxicity_syndrome.htm

--- excerpts:

Anemia. Copper is needed for iron metabolism. Therefore, an

important cause of anemia, especially in women, is a copper

imbalance. On a blood test, it looks exactly like an

iron-deficient anemia but it will not respond very well to the

administration of supplemental iron. The copper imbalance

must be corrected and then the anemia vanishes quickly. ...

What is biounavailable copper? In this very common situation,

copper is present in excess in the body, but it cannot be

utilized well. The reason it occurs is that minerals such as

copper must be bound and transported within the body.

Biounavailability often occurs due to a deficiency of the

copper-binding proteins, ceruloplasmin or metallothionein.

Without sufficient binding proteins, unbound copper may

circulate freely in the body, where it may accumulate

primarily in the liver, brain and female organs.

When copper is biounavailable, one may have symptoms of both

copper toxicity and copper deficiency. ...

Liver and transporter problems. A sluggish liver or weak

adrenal glands may cause copper to build up in the tissues.

Other problems with metallothionein or ceruloplasmin often

contribute to copper toxicity or biounavailability.

_______________________________________________________________

COPPER TOXICITY

http://www.custommedicine.com.au/blog/2007/03/30/copper-toxicity/

--- excerpts:

Copper ingestion and absorption is very easy and is inhibited

by zinc and molybdenum. The presence of estrogens and

xenoestrogens seems to block the body's ability to excrete

copper. Therefore if you are low in zinc and molybdenum and

are exposed to estrogens/xenoestrogens or estrogen dominant it

could potentially lead to copper overload because of copper

retention.

... Copper toxicity appears to be far more common than copper

deficiencies and can be just as devastating to your health as

heavy metals such as mercury and lead can be. Unfortunately

for many copper toxicity is largely being ignored by the

mainstream medical profession.

The main problems related to copper toxicity include:

(1) Hormone Imbalances -- blocks T4 production and conversion

into T3, by blocking iron it also inhibits steroid hormone

pathway resulting with low hormone levels.

(2) Fatigue -- by blocking iron absorption, storage and its

effects in the mitochondria, also blocks magnesium, and

disrupts hormone production.

(3) Anxiety/Depression -- it reduces serotonin production

(4) Joint Pains

(5) Poor Immunity -- viral, fungal and yeast infections

(6) Poor sleep -- it blocks melatonin production

(7) Hypoglycemia -- by impairing digestion effects sugar

absorption, also increases insulin.

(8) Cancer -- it is involved in angiogenesis which promotes

cancer growth.

(9) Allergies/Intolerance -- it increases histamine

production

[...]

---

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Sol,

being a C282Y heterozygyte I share your view, and Usually simplify it to people

who load iron or have an active loading mechanism need ferritin lower, people

who don't load iron / don't have active iron loading mechanisms from food etc

need higher ferritin readings to work properly with thyroid.

Now how those mechanisms actually work aside from that we know there are

mutations on the Hfe gene, I don't know. but I do know I have to remind people,

one ferritin range for loaders, and anotehr for non loaders, not " one range to

make thyroid work properly " beyond that, the digestive process and adding in HCl

may help for some, but at what point can a person not absorb ingested iron at

all? hmmm it's tricky. Are there other digestive malabsorption issues? or is it

just ferritin? is there something else binding with the iron perhaps? therefore

would an IV work? I know one member it didn't work for and she left RTH and I've

not heard from her in over a year :-(

i wish I had a magic wand!!!!!!

Cat

> > I can't find anywhere to get iron IV's but even if I did I don't think

> > they'd give them to me. 29 is not considered anemic, they think it's

> > in the acceptable range. W

> 29 IS acceptable. I know at least one person who keeps her ferritin at

> 30. Even for people with HH that is at the low end, and some might not

> feel well there, but I also know of a person who does fine with

> dessicated thyroid at ferritin of 16-20. The question should be why

> doesn't everyone?

> I can't help but believe there is more going on with iron and thyroid

> than just ferritin being too low. Just because no one seems to know how

> to get low ferritin people to " tolerate " their thyroid meds with low

> ferritin does not at all mean there isn't some other reason which is

> being overlooked. Otherwise no one at all could take thyroid meds with

> very low ferritin, but people DO, and successfully too.

> And the body can have good reasons for keeping ferritin low. Infection,

> cancer, occult internal bleeding. That very low ferritin might interfere

> with thyroid function or thyroid hormone tolerance could be simply a

> side effect of those other reasons. Forcing iron absorption might enable

> better thyroid med tolerance in the short run, but could possibly have

> very dire consequences in the long term.

> I will stress that low ferritin can go right along with heavy iron

> loading elsewhere in the body. That is why I feel ingesting lots of iron

> or using iron IVs can be very risky, unless it is known (known, no

> guessing) that there is no iron overloading taking place out of sight.

> That is why ferritin alone is an inadequate test in the lower end of the

> ranges.

> I realize my opinion is not widely shared on this list, but it IS my

> opinion, and in my iron readings I have as yet not found reason to

> change those opinions, in fact the more I read the more scared I am of

> too much iron.

> sol

>

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Sol,

being a C282Y heterozygyte I share your view, and Usually simplify it to people

who load iron or have an active loading mechanism need ferritin lower, people

who don't load iron / don't have active iron loading mechanisms from food etc

need higher ferritin readings to work properly with thyroid.

Now how those mechanisms actually work aside from that we know there are

mutations on the Hfe gene, I don't know. but I do know I have to remind people,

one ferritin range for loaders, and anotehr for non loaders, not " one range to

make thyroid work properly " beyond that, the digestive process and adding in HCl

may help for some, but at what point can a person not absorb ingested iron at

all? hmmm it's tricky. Are there other digestive malabsorption issues? or is it

just ferritin? is there something else binding with the iron perhaps? therefore

would an IV work? I know one member it didn't work for and she left RTH and I've

not heard from her in over a year :-(

i wish I had a magic wand!!!!!!

Cat

> > I can't find anywhere to get iron IV's but even if I did I don't think

> > they'd give them to me. 29 is not considered anemic, they think it's

> > in the acceptable range. W

> 29 IS acceptable. I know at least one person who keeps her ferritin at

> 30. Even for people with HH that is at the low end, and some might not

> feel well there, but I also know of a person who does fine with

> dessicated thyroid at ferritin of 16-20. The question should be why

> doesn't everyone?

> I can't help but believe there is more going on with iron and thyroid

> than just ferritin being too low. Just because no one seems to know how

> to get low ferritin people to " tolerate " their thyroid meds with low

> ferritin does not at all mean there isn't some other reason which is

> being overlooked. Otherwise no one at all could take thyroid meds with

> very low ferritin, but people DO, and successfully too.

> And the body can have good reasons for keeping ferritin low. Infection,

> cancer, occult internal bleeding. That very low ferritin might interfere

> with thyroid function or thyroid hormone tolerance could be simply a

> side effect of those other reasons. Forcing iron absorption might enable

> better thyroid med tolerance in the short run, but could possibly have

> very dire consequences in the long term.

> I will stress that low ferritin can go right along with heavy iron

> loading elsewhere in the body. That is why I feel ingesting lots of iron

> or using iron IVs can be very risky, unless it is known (known, no

> guessing) that there is no iron overloading taking place out of sight.

> That is why ferritin alone is an inadequate test in the lower end of the

> ranges.

> I realize my opinion is not widely shared on this list, but it IS my

> opinion, and in my iron readings I have as yet not found reason to

> change those opinions, in fact the more I read the more scared I am of

> too much iron.

> sol

>

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ferritin is a storage protein, the test doesn't work that way.

by donating, your whole panel would have changed hopefully as you draw off some

blood and your body begins the process to make new blood to replace it, at some

point, drawing onthe stored ferritin in order to do so. Just when it will is

anybodies guess as is whether or not the ferritin level will raise briefly as

part of a self protection mechanism if the body detects teh blood letting as an

attack, ferritin is considered a volatile and unreliable test to be used in this

manner, you change teh blood volume, you get inflamed, infected stressed,

anything it can change. The only use really is if it is consistently below range

OR it can be read in conjunction with the rest of the full fasting ferritin

panel in order to see what's in serum, what's in stores, how much transferrin

there it, how saturated it is, and the cbc, how many rbc's how many wbc', whats

the PCV and so on and so on. ferritin on it's own doesn't say much unless

consistently high or low, sorry I'm not explaining it very well. :-( but I hope

that helps... a bit?... :-)

Cat

>

>

> > In the reverse way, that is what I was hoping to do. Get tested just

> > after a blood donation, then again 2 months later just before the next

> > one.

>

> I got ferritin rechecked after a donation and it went up. I think maybe you

have to give it awhile to balance itself.

>

> Dorothy

>

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apologies for posting twice, and that doesn't read right, sorry again,

I'll try again once I've slept :D

sorry gang!!

Cat

> > > I can't find anywhere to get iron IV's but even if I did I don't think

> > > they'd give them to me. 29 is not considered anemic, they think it's

> > > in the acceptable range. W

> > 29 IS acceptable. I know at least one person who keeps her ferritin at

> > 30. Even for people with HH that is at the low end, and some might not

> > feel well there, but I also know of a person who does fine with

> > dessicated thyroid at ferritin of 16-20. The question should be why

> > doesn't everyone?

> > I can't help but believe there is more going on with iron and thyroid

> > than just ferritin being too low. Just because no one seems to know how

> > to get low ferritin people to " tolerate " their thyroid meds with low

> > ferritin does not at all mean there isn't some other reason which is

> > being overlooked. Otherwise no one at all could take thyroid meds with

> > very low ferritin, but people DO, and successfully too.

> > And the body can have good reasons for keeping ferritin low. Infection,

> > cancer, occult internal bleeding. That very low ferritin might interfere

> > with thyroid function or thyroid hormone tolerance could be simply a

> > side effect of those other reasons. Forcing iron absorption might enable

> > better thyroid med tolerance in the short run, but could possibly have

> > very dire consequences in the long term.

> > I will stress that low ferritin can go right along with heavy iron

> > loading elsewhere in the body. That is why I feel ingesting lots of iron

> > or using iron IVs can be very risky, unless it is known (known, no

> > guessing) that there is no iron overloading taking place out of sight.

> > That is why ferritin alone is an inadequate test in the lower end of the

> > ranges.

> > I realize my opinion is not widely shared on this list, but it IS my

> > opinion, and in my iron readings I have as yet not found reason to

> > change those opinions, in fact the more I read the more scared I am of

> > too much iron.

> > sol

> >

>

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apologies for posting twice, and that doesn't read right, sorry again,

I'll try again once I've slept :D

sorry gang!!

Cat

> > > I can't find anywhere to get iron IV's but even if I did I don't think

> > > they'd give them to me. 29 is not considered anemic, they think it's

> > > in the acceptable range. W

> > 29 IS acceptable. I know at least one person who keeps her ferritin at

> > 30. Even for people with HH that is at the low end, and some might not

> > feel well there, but I also know of a person who does fine with

> > dessicated thyroid at ferritin of 16-20. The question should be why

> > doesn't everyone?

> > I can't help but believe there is more going on with iron and thyroid

> > than just ferritin being too low. Just because no one seems to know how

> > to get low ferritin people to " tolerate " their thyroid meds with low

> > ferritin does not at all mean there isn't some other reason which is

> > being overlooked. Otherwise no one at all could take thyroid meds with

> > very low ferritin, but people DO, and successfully too.

> > And the body can have good reasons for keeping ferritin low. Infection,

> > cancer, occult internal bleeding. That very low ferritin might interfere

> > with thyroid function or thyroid hormone tolerance could be simply a

> > side effect of those other reasons. Forcing iron absorption might enable

> > better thyroid med tolerance in the short run, but could possibly have

> > very dire consequences in the long term.

> > I will stress that low ferritin can go right along with heavy iron

> > loading elsewhere in the body. That is why I feel ingesting lots of iron

> > or using iron IVs can be very risky, unless it is known (known, no

> > guessing) that there is no iron overloading taking place out of sight.

> > That is why ferritin alone is an inadequate test in the lower end of the

> > ranges.

> > I realize my opinion is not widely shared on this list, but it IS my

> > opinion, and in my iron readings I have as yet not found reason to

> > change those opinions, in fact the more I read the more scared I am of

> > too much iron.

> > sol

> >

>

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apologies for posting twice, and that doesn't read right, sorry again,

I'll try again once I've slept :D

sorry gang!!

Cat

> > > I can't find anywhere to get iron IV's but even if I did I don't think

> > > they'd give them to me. 29 is not considered anemic, they think it's

> > > in the acceptable range. W

> > 29 IS acceptable. I know at least one person who keeps her ferritin at

> > 30. Even for people with HH that is at the low end, and some might not

> > feel well there, but I also know of a person who does fine with

> > dessicated thyroid at ferritin of 16-20. The question should be why

> > doesn't everyone?

> > I can't help but believe there is more going on with iron and thyroid

> > than just ferritin being too low. Just because no one seems to know how

> > to get low ferritin people to " tolerate " their thyroid meds with low

> > ferritin does not at all mean there isn't some other reason which is

> > being overlooked. Otherwise no one at all could take thyroid meds with

> > very low ferritin, but people DO, and successfully too.

> > And the body can have good reasons for keeping ferritin low. Infection,

> > cancer, occult internal bleeding. That very low ferritin might interfere

> > with thyroid function or thyroid hormone tolerance could be simply a

> > side effect of those other reasons. Forcing iron absorption might enable

> > better thyroid med tolerance in the short run, but could possibly have

> > very dire consequences in the long term.

> > I will stress that low ferritin can go right along with heavy iron

> > loading elsewhere in the body. That is why I feel ingesting lots of iron

> > or using iron IVs can be very risky, unless it is known (known, no

> > guessing) that there is no iron overloading taking place out of sight.

> > That is why ferritin alone is an inadequate test in the lower end of the

> > ranges.

> > I realize my opinion is not widely shared on this list, but it IS my

> > opinion, and in my iron readings I have as yet not found reason to

> > change those opinions, in fact the more I read the more scared I am of

> > too much iron.

> > sol

> >

>

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This is interesting Bill, it explains why the iron supplement I have

has copper in it. Though it would help if there was a way to tell if

someone was too high or too low in copper

Elyse

> High copper, or low copper -- both block iron absorption.

>

> Bill

>

> COPPER TOXICITY SYNDROME

> http://drlwilson.com/Articles/copper_toxicity_syndrome.htm

>

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This is interesting Bill, it explains why the iron supplement I have

has copper in it. Though it would help if there was a way to tell if

someone was too high or too low in copper

Elyse

> High copper, or low copper -- both block iron absorption.

>

> Bill

>

> COPPER TOXICITY SYNDROME

> http://drlwilson.com/Articles/copper_toxicity_syndrome.htm

>

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A good doctor would test copper, zinc, and iron to see what's going on since the

three of these affect each other.

HypoT's have gut issues, malabsorption, and possible IBS(especially with hashis)

which will affect absorption of everything.

Of course, there are also bleeding, cancer, parasites etc. etc.

A friend of mine has a doctor who gives his wife an iron IV every 6-9 months

based on symptoms. He can't figure out why she won't absorb iron. Sometimes

there isn't an answer.

>

> > High copper, or low copper -- both block iron absorption.

> >

> > Bill

> >

> > COPPER TOXICITY SYNDROME

> > http://drlwilson.com/Articles/copper_toxicity_syndrome.htm

> >

>

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> How much blood do they take for a donation? Wouldn't that be enough

> to affect levels in someone that is low?

> Elyse

If I were low, I would not be donating blood once a month. My ferritin was

196(11-307). After donating blood twice only 2 wks apart it was 222. This was

about 1 1/2 weeds after donating. Did not have CBC with first, but with 2nd

Hemoglobin was 13.5 (11/5-16.0). Since then, donating once a month, Hgb is 14.5.

According to the iron overload site, one donation is good for a ferritin drop of

25. So I am figuring about 2 more donations which will make 6, I will wait a

bit and recheck ferritin. Not claiming to know all that much about what I am

doing. I can get away with monthly donations because United Blood services and

Red Cross records are not connected. I think if my Hgb is OK when I donate there

should not be a problem, since it seems to recover in 1 month.

Dorothy

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Bill,

That is very interesting about the copper. DH and I are both having problems

with thyroid meds, he had high estrogen on saliva labs, and I am having periods

of estrogen dominance (it comes and goes). How do you test copper?

Thanks,

> >

> >... I also know of a person who does fine with desiccated thyroid at ferritin

of 16-20. The question should be why doesn't everyone?

> >

> >I can't help but believe there is more going on with iron and thyroid than

just ferritin being too low. Just because no one seems to know how to get low

ferritin people to " tolerate " their thyroid meds with low ferritin does not at

all mean there isn't some other reason which is being overlooked. Otherwise no

one at all could take thyroid meds with very low ferritin, but people DO, and

successfully too. ...

>

>

> High copper, or low copper -- both block iron absorption.

>

> Bill

>

>

>

> COPPER TOXICITY SYNDROME

> http://drlwilson.com/Articles/copper_toxicity_syndrome.htm

>

> --- excerpts:

>

> Anemia. Copper is needed for iron metabolism. Therefore, an

> important cause of anemia, especially in women, is a copper

> imbalance. On a blood test, it looks exactly like an

> iron-deficient anemia but it will not respond very well to the

> administration of supplemental iron. The copper imbalance

> must be corrected and then the anemia vanishes quickly. ...

>

> What is biounavailable copper? In this very common situation,

> copper is present in excess in the body, but it cannot be

> utilized well. The reason it occurs is that minerals such as

> copper must be bound and transported within the body.

>

> Biounavailability often occurs due to a deficiency of the

> copper-binding proteins, ceruloplasmin or metallothionein.

> Without sufficient binding proteins, unbound copper may

> circulate freely in the body, where it may accumulate

> primarily in the liver, brain and female organs.

>

> When copper is biounavailable, one may have symptoms of both

> copper toxicity and copper deficiency. ...

>

> Liver and transporter problems. A sluggish liver or weak

> adrenal glands may cause copper to build up in the tissues.

> Other problems with metallothionein or ceruloplasmin often

> contribute to copper toxicity or biounavailability.

>

> _______________________________________________________________

>

>

> COPPER TOXICITY

> http://www.custommedicine.com.au/blog/2007/03/30/copper-toxicity/

>

> --- excerpts:

>

> Copper ingestion and absorption is very easy and is inhibited

> by zinc and molybdenum. The presence of estrogens and

> xenoestrogens seems to block the body's ability to excrete

> copper. Therefore if you are low in zinc and molybdenum and

> are exposed to estrogens/xenoestrogens or estrogen dominant it

> could potentially lead to copper overload because of copper

> retention.

>

> ... Copper toxicity appears to be far more common than copper

> deficiencies and can be just as devastating to your health as

> heavy metals such as mercury and lead can be. Unfortunately

> for many copper toxicity is largely being ignored by the

> mainstream medical profession.

>

> The main problems related to copper toxicity include:

>

> (1) Hormone Imbalances -- blocks T4 production and conversion

> into T3, by blocking iron it also inhibits steroid hormone

> pathway resulting with low hormone levels.

>

> (2) Fatigue -- by blocking iron absorption, storage and its

> effects in the mitochondria, also blocks magnesium, and

> disrupts hormone production.

>

> (3) Anxiety/Depression -- it reduces serotonin production

>

> (4) Joint Pains

>

> (5) Poor Immunity -- viral, fungal and yeast infections

>

> (6) Poor sleep -- it blocks melatonin production

>

> (7) Hypoglycemia -- by impairing digestion effects sugar

> absorption, also increases insulin.

>

> (8) Cancer -- it is involved in angiogenesis which promotes

> cancer growth.

>

> (9) Allergies/Intolerance -- it increases histamine

> production

>

>

> [...]

>

>

>

>

>

> ---

>

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dorothyroeder wrote:

>> In the reverse way, that is what I was hoping to do. Get tested just

>> after a blood donation, then again 2 months later just before the next

>> one.

>>

>

> I got ferritin rechecked after a donation and it went up. I think maybe you

have to give it awhile to balance itself.

>

I remember that!

I wonder if that can happen with later donations? I'm doing my 4th in a

couple weeks.

sol

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dorothyroeder wrote:

>> In the reverse way, that is what I was hoping to do. Get tested just

>> after a blood donation, then again 2 months later just before the next

>> one.

>>

>

> I got ferritin rechecked after a donation and it went up. I think maybe you

have to give it awhile to balance itself.

>

I remember that!

I wonder if that can happen with later donations? I'm doing my 4th in a

couple weeks.

sol

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dorothyroeder wrote:

>> In the reverse way, that is what I was hoping to do. Get tested just

>> after a blood donation, then again 2 months later just before the next

>> one.

>>

>

> I got ferritin rechecked after a donation and it went up. I think maybe you

have to give it awhile to balance itself.

>

I remember that!

I wonder if that can happen with later donations? I'm doing my 4th in a

couple weeks.

sol

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macedgeca wrote:

> How much blood do they take for a donation? Wouldn't that be enough

> to affect levels in someone that is low?

> Elyse

>

>

Usually for a normal whole blood donation they take 1 unit which is

approx a pint.

There are other forms of donation, though.

sol

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macedgeca wrote:

> How much blood do they take for a donation? Wouldn't that be enough

> to affect levels in someone that is low?

> Elyse

>

>

Usually for a normal whole blood donation they take 1 unit which is

approx a pint.

There are other forms of donation, though.

sol

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macedgeca wrote:

> How much blood do they take for a donation? Wouldn't that be enough

> to affect levels in someone that is low?

> Elyse

>

>

Usually for a normal whole blood donation they take 1 unit which is

approx a pint.

There are other forms of donation, though.

sol

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catliciousoz wrote:

> Sol,

>

> being a C282Y heterozygyte I share your view, and Usually simplify it to

people who load iron or have an active loading mechanism need ferritin lower,

people who don't load iron / don't have active iron loading mechanisms from food

etc need higher ferritin readings to work properly with thyroid.

>

But the trick is to know if you are an iron loader or not, and ferritin

alone doesn't tell that even when ferritin is low.

That is all I'm saying, ferritin alone isn't safe to rely on. And I get

the distinct impression people ARE relying on ferritin alone to tell

them if they are iron loading or not.

sol

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catliciousoz wrote:

> Sol,

>

> being a C282Y heterozygyte I share your view, and Usually simplify it to

people who load iron or have an active loading mechanism need ferritin lower,

people who don't load iron / don't have active iron loading mechanisms from food

etc need higher ferritin readings to work properly with thyroid.

>

But the trick is to know if you are an iron loader or not, and ferritin

alone doesn't tell that even when ferritin is low.

That is all I'm saying, ferritin alone isn't safe to rely on. And I get

the distinct impression people ARE relying on ferritin alone to tell

them if they are iron loading or not.

sol

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