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HEALTH TIPS -10/11/01

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MRI IMPROVEMENTS ON THE HORIZON

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> Using a technique similar to magnetic resonance imaging

> but at 10,000 times the resolution, physicists at North-

> western University have shed new light on a high-tempera-

> ture superconductor with potential medical applications.

> The system might one day benefit hospital MRI technol-

> ogies and the patients who rely on them, said

> Halperin, professor of physics and astronomy. " Currently,

> hospitals use low-temperature superconductors in MRI,

> but high-temperature superconductors -- a relatively new

> discovery -- may be a better material, with the bonus of

> requiring less cooling, thus reducing costs, " said

> Halperin, author of the article in the British journal

> Nature. To advance its potential application in future

> technologies, the researchers first need to understand

> the physical properties of these materials and especial-

> ly how they behave in the presence of very large mag-

> netic fields.

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>

BIRTH CONTROL RING

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> There’s a new birth control option for women: a vagianl

> ring that provides month-long protection. The device

> has received approval from the U.S. Food and Drug Admin-

> istration. It is called NuvaRing®(etonogestrel/ethinyl

> estradiol vaginal ring). The flexible, transparent ring

> works by releasing a continuous low dose of estrogen and

> progestin over a 21-day period. " NuvaRing® truly is

> birth control for the new millennium, " said Dr. Larry

> Seidman, clinical assistant professor of obstetrics and

> gynecology at MCP-Hahnemann School of Medicine in

> Philadelphia. " Women are always searching for more con-

> venient contraceptive options. Like the pill, NuvaRing®

> is effective yet is administered only once a month and

> gives women more freedom and allows them to be spon-

> taneous.”

>

>

SECOND ALS GENE IDENTIFIED

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> Scientists have identified a second gene implicated in

> amyotrophic lateral slerosis, or ALS. The discovery

> identifies the second known cause of the fatal, poorly

> understood disease. ALS, also known as Lou Gehrig's

> disease, kills muscle-controlling nerve cells , called

> motor neurons, in the spinal cord and brain. Eventually

> there is paralysis and respiratory failure. Most of the

> time, ALS has no obvious cause, but it's genetic in

> about 10 percent of cases. Until now, defects in the

> SOD1 gene on chromosome 21 were the only known cause of

> ALS. Now, two teams report that defects in a previously

> unknown gene on chromosome 2 cause a rare form of ALS

> called ALS2. The finding may provide an important new

> clue to the ALS disease process. " Knowing so little

> about what causes ALS has severely hindered the develop-

> ment of effective therapies. These two studies on ALS2

> may lead to general insights about ALS and how to treat

> it, " said Sharon Hesterlee, director of research develop-

> ment for the Muscular Dystrophy Association.

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CHEMICALS PREVENT BRAIN CELL DEATH

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> Two plant-derived chemicals can reduce the damage from a

> simulated stroke in cultured mouse brain cells, a study

> shows. Further research might lead to a new class of

> stroke drugs, the researchers said. The chemicals work

> by shutting down the enzyme PARG (Poly-ADP-Ribose Glyco-

> hydrolase). It contributes to stroke-related cell death,

> said lead study author Dr. Swanson, acting chief

> of neurology at San Francisco Veterans Affairs Medical

> Center and University of California, San Francisco, pro-

> fessor of neurology. " By inhibiting PARG we can protect

> brain cells from the type of cell death that happens

> during a stroke. This same death mechanism is seen in

> several other disorders, such as diabetes, inflammation,

> and heart attack. "

>

>

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