Guest guest Posted March 16, 2001 Report Share Posted March 16, 2001 Hi Joe! Geoff Crenshaw here. Try altering your dosage regimen *if* you find the pain intolerable. What you are describing seems to match what is commonly called a " Herx, " an inflammatory and system response to the " good " actions of the drug. If you need to alter, check out http://www.rheumatic.org/ > protocol and review it. The usual routine would be to cut your frequency of dosing to M-W-F and if that is still too uncomfortable, to cut the amount to 100mg/day, thus you would go from 200mg/daily to 100mg M-W-F. From that point you would gradually build up. HTH. Regards, ----------------------- Geoff ** Usual Disclaimers ** ----------------------- How can you have hope? Get under the blood of the Passover Lamb. EXO 12:7-3 / MAR 14:24 / REV 12:11 http://www.healingyou.org/ Nonprofit: Herbs, Homeopathics & supp's. http://www.800-800-cruise.com/index-aff.html Make money & travel! http://www.800-800-cruise.com/ Over a MILLION travel deals! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2001 Report Share Posted March 16, 2001 T Croteau wrote: > Hi, > I am about to start my Minocin and was just wondering.... > I have pain but mainly where I have damage...weight bearing or twisting the wronge > way...... I do have some nodules and swelling (minor BUT my index and mid fingers have > been Puffy " for 6 years) I seem to have permanent residual swelling , never > gets better or worse... Will the puffiness and/or nodules ever go away.. > Debi > In Sunny Alberta > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2001 Report Share Posted March 16, 2001 Dear Debi, I am sure they will. I had nodules on my elbows and I thought they were permanent, but they just dissolved and disappeared. And the swelling will go down, too, as you get well. love, Gloria Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2001 Report Share Posted April 12, 2001 Hey there, Here's what I remember in the volumes of studying I've been doing lately.....we should be taking Lederle Minocin.....or the lederle generic........nothing other than these two. The lederle Minocin I have is a dark green see through half with a light green opaque half and there are pellets inside.....I seem to remember reading somwhere that the pellets are absorbed differently than the powder. The doctor did specify pellet on the scrip so maybe it's possible that it also comes in powder? Anyway I do remember reading somewhere that the pellet form is the one we want. Hope this helped, Hugs, Dee Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 12, 2001 Report Share Posted April 12, 2001 You dont happen to be in canada do you? Canada Lederle is powder and they dont offer pelletized. Im sure pelletized is timed release, staying in your body for 12-16 hours where the powder stays for 4 hours. rheumatic Minocin > Just called pharmacist...he says the powder (Lederle) > and the pellets (PMS)generic...are the same ...the pellets > he said...are not time released. > So now what? > Debi > > > To unsubscribe, email: rheumatic-unsubscribeegroups > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 19, 2001 Report Share Posted April 19, 2001 Group, I found this information on minocin from the following site: http://members.aol.com/webmedic4u/Minocin.html 50 mg: Each orange hard shell capsule, printed “Lederle M2” and “MINOCIN 50 mg”, contains: minocycline HCl equivalent to minocycline 50 mg. Energy: <4.2 kJ (1 kcal). Tartrazine-free. Bottles of 100 and 500. 100 mg: Each orange-purple hard shell capsule, printed “Lederle M4” and “MINOCIN 100 mg”, contains: minocycline HCl equivalent to minocycline 100 mg. Energy: <4.2 kJ (1 kcal). Tartrazine-free. Bottles of 50, 100 and 500. NOTICE: they did not mention what was inside the capsule - pellets or powder? carol/piney Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 19, 2002 Report Share Posted July 19, 2002 Hi Ute, I too use the minocin (lederle) which I bought from Costco last january - $992 for 300 capsules- so the same as your price. I hope the mino-doxy combo works for you, the doc I see has had some success with that regimen. I was on it from Jan through last month and then went back to the 200mg of minocin, since I seemed to be in the RA "doldrums" - Best to you , Ute Reeves wrote: Dear group, I'm a little slow in giving my input on the recent Minocin discussion. I also found that pharmacies are not carrying Minocin. I sent my husband to the neighborhood pharmacy to inquire how much the Minocin would cost. He came back all smiling, it was thirty some dollars for 60. I knew that was not an accurate quote for brand name Minocin. So I called the pharmacist and he admitted it was Minocycline. He said they did not even carry the Minocin because it was so expensive and insurances were not covering it. This worries me some because I am wondering who, other than us on AP, has a need for brand name Minocin. The manufacturer might decide to discontinue production. But we are okay for now. I get my Minocin mail order from 's Pharmacy in North Carolina. It costs about $200 for 60 capsules. I have been getting the pelletized Minocycline from them (until they ran out) much more reasonable than I could get locally. They are also pleasant to deal with. Perhaps we can share with each other how much we pay for Minocin to find the cheapest source. I am having a hard time coping with the price difference. I have been doing well on the pelletized Minocycline and just don't have the courage to see if the powdered stuff will work for me. After 4 years on AP, doing quite well pain and swelling wise for a long time, I finally overcame the fatigue. I am actually able to keep up with my garden chores this summer and have FUN doing it! Since I can't afford the Mino dosage as before (200mg every other day) I decided to split Mino and Doxy half and half. Mino in the morning, Doxycycline in the evening, every other day. We will see how that goes. I got the idea here, thank you for sharing! Take care, Ute Reeves RA; AP since 98 To unsubscribe, email: rheumatic-unsubscribeegroups Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2002 Report Share Posted July 20, 2002 Hummm...personally I have been on Minocycline for at least a year now...I haven't noticed any difference. My progress has continued just as when I was on the Minocin...Being in the navy I pretty much have to take what they give me and I am thankful that they at least have agreed to keep me on Minocycline. Now....I wish they would still give me prilosec instead of acidifex (for my acid reflux)....THERE I definately see a difference but alas....they say prilosec is just too expensive and acidifex is the same....I don't think so.......they don't feel the burning like I do... Blessings and health to all! Tony AP since Oct 1999, getting better and better...... Acidifex 20mg twice a day Zocor 20mg once a day Minocycline 100mg twice a day Celebrex 200mg twice a day (when I need it...which isn't too often anymore). Zestril 20mg once a day -----Original Message-----From: Ute Reeves [mailto:nowyoga@...]Sent: Friday, July 19, 2002 2:53 PMrheumatic Subject: rheumatic MinocinDear group,I'm a little slow in giving my input on the recent Minocin discussion. Ialso found that pharmacies are not carrying Minocin. I sent my husband tothe neighborhood pharmacy to inquire how much the Minocin would cost. Hecame back all smiling, it was thirty some dollars for 60. I knew that wasnot an accurate quote for brand name Minocin. So I called the pharmacistand he admitted it was Minocycline. He said they did not even carry theMinocin because it was so expensive and insurances were not covering it.This worries me some because I am wondering who, other than us on AP, has aneed for brand name Minocin. The manufacturer might decide to discontinueproduction. But we are okay for now.I get my Minocin mail order from 's Pharmacy in North Carolina. Itcosts about $200 for 60 capsules. I have been getting the pelletizedMinocycline from them (until they ran out) much more reasonable than Icould get locally. They are also pleasant to deal with.Perhaps we can share with each other how much we pay for Minocin to findthe cheapest source. I am having a hard time coping with the pricedifference. I have been doing well on the pelletized Minocycline and justdon't have the courage to see if the powdered stuff will work for me. After4 years on AP, doing quite well pain and swelling wise for a long time, Ifinally overcame the fatigue. I am actually able to keep up with my gardenchores this summer and have FUN doing it! Since I can't afford the Mino dosage as before (200mg every other day) Idecided to split Mino and Doxy half and half. Mino in the morning,Doxycycline in the evening, every other day. We will see how that goes. Igot the idea here, thank you for sharing!Take care,Ute ReevesRA; AP since 98To unsubscribe, email: rheumatic-unsubscribeegroups Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2002 Report Share Posted July 20, 2002 Tony, Your acid reflux may very well be tied in with the medications you are on. If you can possibly pull it off, go to a Certified Clinical Nutritionist and have him/her go over your supplements. If you do not have enough HCL in the gut system, you will not be able to eliminate many of the organisms. Also, I didn't notice you were on any probiotics, and larger doses of such as OTC Solaray Multidophilus powder once or twice a day, with meals, may help greatly with that reflux, by replacing some good bacteria -- the bad ones could be adding to the reflux. The Zocor you are on has a very negative effect on the body. The CCN might help you with this, too. Kyolic garlic in the green wrapper could be a better choice for this (two 3x a day), without the dangerous side effects. Zocor wipes out the ATP, which you and your heart desperately need. Go to www.mercola.com and do a search on " statins. " His articles are very good on this subject. There are several more RX meds on your list that will keep your body from making the necessary repairs. Looks like whoever prescribed these are just trying to contol symptoms and not fix the problems, and may be causing you more problems. Forgive me, I'm not a professional health person. This is not advice. Just brainstorming with you. bg > Hummm...personally I have been on Minocycline for at least a year now...I > haven't noticed any difference. My progress has continued just as when I > was on the Minocin...Being in the navy I pretty much have to take what they > give me and I am thankful that they at least have agreed to keep me on > Minocycline. Now....I wish they would still give me prilosec instead of > acidifex (for my acid reflux)....THERE I definately see a difference but > alas....they say prilosec is just too expensive and acidifex is the > same....I don't think so.......they don't feel the burning like I do... > Blessings and health to all! > Tony > AP since Oct 1999, getting better and better...... > Acidifex 20mg twice a day > Zocor 20mg once a day > Minocycline 100mg twice a day > Celebrex 200mg twice a day (when I need it...which isn't too often anymore). > Zestril 20mg once a day > > rheumatic Minocin > > > Dear group, > I'm a little slow in giving my input on the recent Minocin discussion. I > also found that pharmacies are not carrying Minocin. I sent my husband to > the neighborhood pharmacy to inquire how much the Minocin would cost. He > came back all smiling, it was thirty some dollars for 60. I knew that was > not an accurate quote for brand name Minocin. So I called the pharmacist > and he admitted it was Minocycline. He said they did not even carry the > Minocin because it was so expensive and insurances were not covering it. > This worries me some because I am wondering who, other than us on AP, has > a > need for brand name Minocin. The manufacturer might decide to discontinue > production. But we are okay for now. > > I get my Minocin mail order from 's Pharmacy in North Carolina. It > costs about $200 for 60 capsules. I have been getting the pelletized > Minocycline from them (until they ran out) much more reasonable than I > could get locally. They are also pleasant to deal with. > > Perhaps we can share with each other how much we pay for Minocin to find > the cheapest source. I am having a hard time coping with the price > difference. I have been doing well on the pelletized Minocycline and just > don't have the courage to see if the powdered stuff will work for me. > After > 4 years on AP, doing quite well pain and swelling wise for a long time, I > finally overcame the fatigue. I am actually able to keep up with my garden > chores this summer and have FUN doing it! > Since I can't afford the Mino dosage as before (200mg every other day) I > decided to split Mino and Doxy half and half. Mino in the morning, > Doxycycline in the evening, every other day. We will see how that goes. I > got the idea here, thank you for sharing! > > Take care, > Ute Reeves > RA; AP since 98 > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 20, 2002 Report Share Posted July 20, 2002 BG, Thanks for the info....actually I think most doctors try to treat the symptoms...as for the acid reflux that started long before I was diagnosed with RA...I will check out the other info you passed on though....tks again. rheumatic Minocin> > > Dear group,> I'm a little slow in giving my input on the recent Minocin discussion. I> also found that pharmacies are not carrying Minocin. I sent my husband to> the neighborhood pharmacy to inquire how much the Minocin would cost. He> came back all smiling, it was thirty some dollars for 60. I knew that was> not an accurate quote for brand name Minocin. So I called the pharmacist> and he admitted it was Minocycline. He said they did not even carry the> Minocin because it was so expensive and insurances were not covering it.> This worries me some because I am wondering who, other than us on AP, has> a> need for brand name Minocin. The manufacturer might decide to discontinue> production. But we are okay for now.> > I get my Minocin mail order from 's Pharmacy in North Carolina. It> costs about $200 for 60 capsules. I have been getting the pelletized> Minocycline from them (until they ran out) much more reasonable than I> could get locally. They are also pleasant to deal with.> > Perhaps we can share with each other how much we pay for Minocin to find> the cheapest source. I am having a hard time coping with the price> difference. I have been doing well on the pelletized Minocycline and just> don't have the courage to see if the powdered stuff will work for me.> After> 4 years on AP, doing quite well pain and swelling wise for a long time, I> finally overcame the fatigue. I am actually able to keep up with my garden> chores this summer and have FUN doing it!> Since I can't afford the Mino dosage as before (200mg every other day) I> decided to split Mino and Doxy half and half. Mino in the morning,> Doxycycline in the evening, every other day. We will see how that goes. I> got the idea here, thank you for sharing!> > Take care,> Ute Reeves> RA; AP since 98> > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2002 Report Share Posted October 2, 2002 on 10/2/02 10:18 AM, jimbo1734683, at jimbo1734683@..., wrote: > I just started taking Minocin on Monday of this week. > One pill on Monday, Wed, Friday and was wondering is it normal to > loose your interest in eating? I had similar problems when I started mino. It still, after 3 years, effects my sense of taste. Do you have a bit of a funny taste in your mouth? I don't like really strong cough drops, like Halls, because they leave my mouth and tongue feeling weird afterward. Minocin does something similar. When i started mino, I was using a higher dose than you, I didn't herx, but the funny taste, and a little queasiness and reduced appetite were my main side effects. The queasiness lessoned as the arthritis symptoms improved, so this may have been a slow, drawn-out herx-like symptom. The funny taste never went away. I find if I take the mino at bedtime (about 30 minutes before lying down, to avoid esophagus problems) I have the fewest effects. If I take mino in the morning, it's hard to eat all day. > I just don't seem to be hungry either in the morning or at night. HTH -- Jean jpro2@... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 4, 2002 Report Share Posted October 4, 2002 Jim, It's ok to take supplements as long as you keep that 2 hour time window. I would take it slow with increasing the dosage so you don't cause yourself unecessary discomfort. Regards, Dee rheumatic Minocin > I just taking minocin and I always make sure to leave a two hour > window before eating but my question is when you are taking minocin > can you still take vitamins as long as you wait the two hours or > should you not take them at all? > > Minocin really seems to be effecting me in a much different way > than the tetracycline did because now I never feel like eating. > > Great way to loose weight but how long does this last? > > I really do miss eating!!!!!!!!!!!! > > I started taking one 100mg pill three days a week to start and maybe > in a few weeks I will try taking two pills a day. > > I am starting slow because after all the flairs over the past few > months I really want to be careful. I do not want to go through that > again. > > I am just now able to walk without to much pain in my feet and knees. > > Walking is fine I just do not try and bend down because I have a very > hard time getting back up. > > It's nice to see many of the old names on this wonderful > web site. > > Have a great day. Jim Hill > > > > To unsubscribe, email: rheumatic-unsubscribeegroups > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2002 Report Share Posted October 5, 2002 Just a note - low zinc levels can affect the appetite. rheumatic Minocin > I just taking minocin and I always make sure to leave a two hour > window before eating but my question is when you are taking minocin > can you still take vitamins as long as you wait the two hours or > should you not take them at all? > > Minocin really seems to be effecting me in a much different way > than the tetracycline did because now I never feel like eating. > > Great way to loose weight but how long does this last? > > I really do miss eating!!!!!!!!!!!! > > I started taking one 100mg pill three days a week to start and maybe > in a few weeks I will try taking two pills a day. > > I am starting slow because after all the flairs over the past few > months I really want to be careful. I do not want to go through that > again. > > I am just now able to walk without to much pain in my feet and knees. > > Walking is fine I just do not try and bend down because I have a very > hard time getting back up. > > It's nice to see many of the old names on this wonderful > web site. > > Have a great day. Jim Hill > > > > To unsubscribe, email: rheumatic-unsubscribeegroups > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2002 Report Share Posted October 5, 2002 -Hi Jim, Well, I take vitamins but I take then before my breakfast and before dinner.Then I take minocin 2hrs later. Have you tried the old seltzer with the minocin?( make sure there are no electrolytes added as it will interfere with absorption. The nausea wil pass..really and tha apetite will pick up.I think if you increase it now..the herx could intensify. Give it at least another week.( wish I could lose a few lbs <VBG> Just hang tight. many have this syptom at the beginning and it does leave.I remember a posted saying he needed to gaet donnatal as it was wicked for him. Kep doing what you are doing. Minocin is stronger..( the pleetes allow more to be asborbed) You shouold do a bit better Marge -- In rheumatic@y..., " jimbo1734683 " <jimbo1734683@y...> wrote: > I just taking minocin and I always make sure to leave a two hour > window before eating but my question is when you are taking minocin > can you still take vitamins as long as you wait the two hours or > should you not take them at all? > > Minocin really seems to be effecting me in a much different way > than the tetracycline did because now I never feel like eating. > > Great way to loose weight but how long does this last? > > I really do miss eating!!!!!!!!!!!! > > I started taking one 100mg pill three days a week to start and maybe > in a few weeks I will try taking two pills a day. > > I am starting slow because after all the flairs over the past few > months I really want to be careful. I do not want to go through that > again. > > I am just now able to walk without to much pain in my feet and knees. > > Walking is fine I just do not try and bend down because I have a very > hard time getting back up. > > It's nice to see many of the old names on this wonderful > web site. > > Have a great day. Jim Hill Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 5, 2002 Report Share Posted October 5, 2002 > ( the pleetes allow more to be asborbed) Boy, those e's sure got after those l's! (VBG!) Geoff soli Deo gloria www.HealingYou.org - Your nonprofit source for remedies and aids in fighting these diseases, information on weaning from drugs, and nutritional kits for repairing damage; 100% volunteer staffed. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 23, 2002 Report Share Posted November 23, 2002 Let me try this again!! I am not the most experienced computer person. For a look at the types of minocin avaliable from this overseas pharmacy go to this website................ <A HREF= " http://www.1drugstore-online.com/showproducts.asp?Page=2 & gcode=009 " >http:/\ /www.1drugstore-online.com/showproducts.asp?Page=2 & gcode=009</A> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2002 Report Share Posted December 17, 2002 Hi Carol, I have in my hand the original bottle given my by my pharmacist (my doc had ordered 90 and as there are 100 caps per bottle and he has no other patients taking Minocin, he gave me the bottle). The manufacturer's label reads, " Minocin, minocycline hydrochloride pellet-filled capsules, 100 mg, Wyeth-Ayerst, Canada Inc, Montreal, Canada " . When I originally requested the pelleted version, I thought it was made by Lederle, but my pharmacist checked and said that Lederle was now under Wyeth-Ayerst. If you like, I can check with my pharmacist and let you know where this Minocin was ordered. I hope this helps. It amazes me that the village drugstore (tiny) that I use was able to get this rx for me in 2 days and others have trouble. I hope this helps. Robyn rheumatic Minocin Hi, I checked with my pharmacist today and I am taking the real generic minocycline originally manufactured by Lederle, Wyeth-Ayerst. The company has changed hands many times and he couldn't remember the actual name of the current company, but said that the product has never changed. Being in Canada, it is the powdered minocycline. He had inquired at his sources for drugs and has had not been able to find out anything about pelleted generic or the real thing being available in Canada. Anyone who can tell me the manufacturer of their pelleted minocin or generic that was bought here in Canada, please email me. Thanks, Carol/Piney Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2005 Report Share Posted July 18, 2005 I took it m-f 100mg and took weekends off. Worked for me. rheumatic Minocin Anyone in the group taking Minocin daily? What would be the benefits/drawbacks to taking it daily? To unsubscribe, email: rheumatic-unsubscribeegroups Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2005 Report Share Posted July 27, 2005 Sally... Like most people I hate to take meds...ANY MEDS. Unfortunately that is impossible with RA. I did meet a lady whose husband takes minocin twice a day and has been on this regime for three years. Everytime his doc cuts him down, the RA comes back. Since he has had no side effects, his doc keeps him at this dose as he feels it is a safer bet than most of the other RA drugs. For me however, I will start on one pill a day if my blood tests in August show my bloodwork in normal ranges. I did well on the maintanance dose for over three years, so hopefully one a day will do the trick this time. In time I hope to find a doc who will take my insurance..tricare...and do IV's. That should really help get rid of whatever bacteria is causing this nasty disease!! At least I am pretty much pain free and enjoying life again. Be Well..................Martha Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2005 Report Share Posted July 27, 2005 Hi Martha; I had the same problem for years also.Each time I cut the methotrexate the SD would come back big time.I maneged to lower my dose from 10mg to 5(once a week) but could not go lower without intolerable pain.Then I found out about MP.I really thought it was off the wall but figured that since I was going nowhere I might as well try cutting out the vit.D...besides I was just plain curious.It took from Sept to Feb to get off and I had no trouble at all but I sure did have the heeby jeebies about it.I had been on 200mg mino for over 4 years with no benefit.Once I found out that this did not help even without the vit.D I changed to 100 mg every other day and things went swimmingly.Since then I have found a good doctor who has added 100mg clindamycin twice a week and I am about 95% normal. Lynne MRSROSE2000@... wrote: > Sally... Like most people I hate to take meds...ANY MEDS. > Unfortunately > that is impossible with RA. I did meet a lady whose husband takes > minocin > twice a day and has been on this regime for three years. Everytime > his doc cuts > him down, the RA comes back. Since he has had no side effects, his doc > keeps him at this dose as he feels it is a safer bet than most of the > other RA > drugs. > For me however, I will start on one pill a day if my blood tests in > August show my bloodwork in normal ranges. I did well on the > maintanance dose > for over three years, so hopefully one a day will do the trick this > time. In > time I hope to find a doc who will take my insurance..tricare...and > do IV's. > That should really help get rid of whatever bacteria is causing this > nasty > disease!! At least I am pretty much pain free and enjoying life > again. Be > Well..................Martha > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 10, 2005 Report Share Posted August 10, 2005 My brother's doctor didn't want to put him on Minocin because so many people have problems with their skin pigment being affected by it. Do others in this group have that problem, too? How common is it? - Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 11, 2005 Report Share Posted August 11, 2005 rheumatic Re: Minocin > My brother's doctor didn't want to put him on Minocin because so many > people > have problems with their skin pigment being affected by it. Do others in > this group have that problem, too? How common is it? > > > > This is called hyperpigmentation. The following is from Frequently Asked > Questions on www.rheumatic.org. 5. WHAT IS HYPERPIGMENTATION? Minocycline can cause discoloration of the skin anywhere on the body. This is called hyperpigmentation. Large daily doses of ascorbic acid (vitamin C) may prevent this phenomenon. (Bowles WH, Baylor College of Dentistry, Texas A & M University System Protection against minocycline pigment formation by ascorbic acid, J Esthet Dent, 10(4):182-6 1998) Dr. A. Franco, a rheumatologist practicing in Riverside, California, says that hyperpigmentation occurs in about 10% to 20% of patients taking minocycline (Minocin) on a daily basis and over one year. Occasionally it may appear earlier. It occurs less frequently with patients taking Minocin on a three times per week basis. It may be necessary to switch to another antibiotic. It is usually reversible after discontinuation of the medication, but fades slowly and sometimes not completely. Dr. Pnina Langevitz in Israel has done three double-blind studies on the use of minocycline in rheumatoid arthritis with some patients on the medication over 5 years. The following is from Langevitz et al à Minocycline in Rheumatoid Arthritis; Isr. J. Med Sci 1996;32:327-330. 'We also observed skin hyperpigmentation in about one third of our patients as a late complication of the therapy. Minocycline related hyperpigmentation of the skin is a well known complication of this agent and can be subdivided into three categories. The first is characterized by dark black-blue macules localized at sites of cutaneous inflammation. . . . . . . . . . . The second type is a more diffuse hyperpigmentation, predominantly on the lower extremeties and on areas exposed to sunlight. . . . . . . . The third form of minocycline-induced hyperpigmentation is the 'muddy skin syndrome' à a dark brown-gray discoloration of the skin generalized over the body, less prominent in non exposed areas. The high incidence of skin hyperpigmentation in our group of patients is probably due to the longer follow-up period than that in other groups, and to sun exposure.' (Patients in this study were on 100 mg. of minocycline twice daily.) > > > > To unsubscribe, email: rheumatic-unsubscribeegroups > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 11, 2005 Report Share Posted August 11, 2005 , Possible skin pigmentation vs joint destruction - where would you put the weight in making a decision? I'm taking my chances to sustain some cosmetic disadvantages to hold the ravages of RA at bay, anytime. Look at the possible side effects of other drugs, do they look more inviting? Take care, Ute At 11:22 AM 8/10/2005, you wrote: >My brother's doctor didn't want to put him on Minocin because so many people >have problems with their skin pigment being affected by it. Do others in >this group have that problem, too? How common is it? > > - > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 11, 2005 Report Share Posted August 11, 2005 I agree with Ute. When I was on all the other " standard " drugs, I felt terrible and still had joint destruction. After four years on minocin, I feel great and have had no further joint problems. Yes I have a few brown splotches on my hands mostly. Lets see now.....A few skin blotches , purely cosmetic....or look great and end up in a nursing home...........Hm-m-m-m. Again everyone must make their own decision. Martha Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 10, 2006 Report Share Posted September 10, 2006 It sounds like you could have a muscle condition like myositis. Maybe time to have your CK (blood test) checked. Quote Link to comment Share on other sites More sharing options...
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