Re: New Drug Info (Florinef) & Advice

March 24, 2012

About 40% of those with Lewy Body Dementia (and a large percentage of those with

Parkinson's Disease) have orthostatic hypotension (OH). Florinef is a common

medication to address this debilitating symptom. Midodrine is another. Florinef

works very quickly.

Unfortunately Sinemet can lower BP. I believe one of Aricept's less common side

effects is a drop in BP. So it's a balancing act with medication.

There's a list of non-drug treatment for OH in this post on the LBDA Forum:

Also, if your husband has surgery again, special precautions need to be taken,

particularly if he has supine hypertension in combination with OH.

>

> Hi Everyone,

> My Bob has been started on Fludrocortisone 0.1MG daily on Wednesday

> the 21st, while hospitalized with a blood infection. They have found

> he has developed postural hypotension. His BP dropped to 54/35 this

> evening at 5:00 pm when they stood him up to transfer to the geri

> chair at the bedside to eat supper, so they put him back to bed just

> that quickly. This morning they had him up walking in the hall with

> the Physical Therapist and he did pretty well with no drop in

> pressure. Anyone here have a LO with Postural Hypotension on

> Fludrocortisone? Does it work and how long does it take to be

> effective? Please share any experience you may have with this issue.

> Thanks,

> Pat

> Wife/caregiver of Bob 75, dx PD 2003, LBD 2009, now in hospital.

>

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