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What Are the Different Types of Insulin?

There are many forms of insulin. They are classified by how fast they start

to work and how long their effects last.

The types of insulin include:

· Rapid acting

· Short acting

· Intermediate acting

· Long acting

· Pre-mixed

What Type of Insulin Is Best Suited For Me?

Your doctor will work with you to prescribe the type of insulin that is best

for you. Deciding what type of insulin might be best for you depend on many

factors, including:

· Your body's individualized response to insulin (how long it takes

insulin to be absorbed in the body and remain active in the body varies

slightly from individual to individual)

· Your own lifestyle choices - for instance, the type of food you

eat, if/how much alcohol you drink, or how much exercise you get - factors that

influence your body's processing of insulin

· How willing you are to give yourself multiple injections per day

· How frequently you are willing to check your blood sugar level

· Your age

· Your blood sugar management goals

As you can now better understand, the type of insulin your doctor may

prescribe for you takes many factors into account and must be individualized

for

you - based on your own body's metabolism of insulin, your lifestyle, treatment

goals, and to some degree, your personal preferences (your willingness to

tightly monitor your blood sugar and give yourself multiple injections).

The following chart lists the types of insulin with details about onset (the

length of time before insulin reaches the bloodstream and begins to lower

blood glucose), peak (the time period when the insulin is the most effective in

lowering blood glucose) and duration (how long insulin continues to lower

blood glucose). These three factors may vary, depending on your body's

response. The final column provides some insight into the " coverage " provided

by the

different insulin types in relation to mealtime.

Type of Insulin & Brand Names

Onset

Peak

Duration

Role in Blood Glucose Management

Rapid Acting

Humalog or lispro

15-30 min.

30 min to 2½ hours

3-5 hours

Rapid-acting insulin covers insulin needs for meals eaten at the same time

as the injection. This type of insulin is used with longer-acting insulin.

Novolog or aspart

10-20 min.

1-3 hours

3-5 hours

Short Acting

Regular ® humulin or novolin

30 min. -1 hour

2-5 hours

5-8 hours

Short-acting insulin covers insulin needs for meals eaten within 30-60

minutes

Velosulin (for use in the insulin pump)

30 min.-1 hour

2-3 hours

2-3 hours

Intermediate Acting

NPH (N)

1-2 hours

4-12 hours

18-24 hours

Intermediate-acting insulin covers insulin needs for about half the day or

overnight. This type of insulin is often combined with rapid- or short-acting

insulin.

Lente (L)

1-2½ hours

3-10 hours

18-24 hours

Long Acting

Ultralente (U)

30 min.-3 hours

10-20 hours

20-36 hours

Long-acting insulin covers insulin needs for about 1 full day. This type of

insulin is often combined, when needed, with rapid- or short-acting insulin.

Lantus

1-1½ hour

No peak time; insulin is delivered at a steady level

20-24 hours

Pre-Mixed*

Humulin 70/30

30 min.

2-4 hours

14-24 hours

These products are generally taken twice a day before mealtime.

Novolin 70/30

30 min.

2-12 hours

Up to24 hours

Novolog 70/30

10-20 min.

1-4 hours

Up to 24

Humulin 50/50

30 min.

2-5 hours

18-24 hours

Humalog mix 75/25

15 min.

30 min.-2½ hours

16-20 hours

* Premixed insulins are a combination of specific proportions of

intermediate-acting and short-acting insulin in one bottle or insulin pen (the

numbers

following the brand name indicate the percentage of each type of insulin).

When do I take my insulin?

Follow your healthcare provider's guidelines on when to take your insulin.

The time span between your insulin injection and meals may vary depending on

the type of insulin you are taking.

In general, however, you should coordinate your insulin injection with when

you want to eat. From the chart above, the " onset " column provides useful

information. Again, the " onset " refers to when the insulin will begin to work

in

your body. You want the insulin to begin working in your body at the same

time your food is being absorbed. This timing of both the self injection and

meal consumption will help avoid low blood glucose levels. So, for example, if

you take Novolog or another rapid-acting insulin, you should self inject

about 15 minutes before mealtime. Short-acting insulins, such as regular

insulin,

should be taken 30 to 60 minutes before a meal. Intermediate-acting insulins

should be taken up to 1 hour prior to a meal.

Premixed insulins. Depending on the product used, premixed solutions should

be taken 15 minutes or 30 to 45 minutes before mealtime.

Exceptions. Injections of long-acting insulins are not " timed " to mealtime

because of their long duration of action. Ultralente is taken once or twice a

day irrespective of mealtime. Lantus is only administered once a day (and

should be administered at the same time each day). Keep in mind that these

long-acting insulins may need to be given with shorter-acting insulin products -

depending on your individual situation - that will likely need to be " timed "

with mealtime.

Finally, the rapid-acting products can also be taken immediately after a

meal (rather than 15 minutes before mealtime). Some products can also be

administered at bedtime. For more information about when to take insulin, read

the

" dosing and administration " section of the insulin product package insert that

came with your insulin product or call your doctor.

Get the facts about insulin.

Learn the basics about diabetes.

View the full table of contents for the Diabetes Guide.

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