Guest guest Posted December 31, 2000 Report Share Posted December 31, 2000 http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uid\ s=9240250 & dopt=Abstract PubMed Nucleotide Protein Genome Structure PopSet Taxonomy OMIM Search PubMed Protein Nucleotide Structure Genome PopSet OMIM Taxonomy for Limits Preview/Index History Clipboard About Entrez Entrez PubMed Overview Help | FAQ New/Noteworthy PubMed Services Journal Browser MeSH Browser Single Citation Matcher Batch Citation Matcher Clinical Queries Cubby Related Resources Order Documents Grateful Med Consumer Health Clinical Alerts ClinicalTrials.gov Privacy Policy Summary Brief Abstract Citation MEDLINE ASN.1 XML/SGML LinkOut Related Articles Protein Links Nucleotide Links Popset Links Structure Links Genome Links OMIM Links 1: Fertil Steril 1997 Aug;68(2):242-5 Related Articles, Books, LinkOut Sonographic assessment of endometrial pattern and thickness in patients treated with clomiphene citrate, human menopausal gonadotropins, and intrauterine insemination.Hock DL, Bohrer MK, Ananth CV, Kemmann EDepartment of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey (UMDNJ)- Wood Medical School, New Brunswick 08901, USA.OBJECTIVE: To analyze the endometrium sonographically in patients undergoing controlled ovarian stimulation with clomiphene citrate (CC) in addition to menotropins to determine the significance of endometrial pattern and thickness on pregnancy rate (PR). DESIGN: A prospective study analyzing patients receiving sequential CC and hMG followed by hCG and IUI. Patients who exhibited homogeneous endometrial patterns were compared with those who had trilaminar patterns visualized by transvaginal sonography at the end of the follicular phase. Endometrial thickness was emphasized in this group of patients. SETTING: Tertiary infertility center. PATIENT(S): All patients receiving sequential CC and hMG therapy at a tertiary infertility center. INTERVENTION(S): All patients received individualized dosing of hMG after 5 days of CC. Transvaginal sonography was performed 15 hours before hCG administration. Intrauterine insemination was performed 36 hours after hCG injection. MAIN OUTCOME MEASURE(S): Occurrence of pregnancy as determined by serially rising beta-hCG titers and sonographic confirmation. RESULT(S): During the study period, 223 patients were analyzed. Fifty patients had a homogeneous endometrium, whereas 173 patients had a trilaminar pattern. In the homogeneous group, the PR was 8%, and in the trilaminar group it was 21%. There was no significant difference in age, parity, diagnosis, peak E2 level, and mature follicle number between the two groups. Although homogeneous patterns were associated with thinner endometrium, no difference in PRs could be discerned within the trilaminar group on the basis of endometrial thickness. CONCLUSION(S): In patients receiving sequential CC and hMG ovarian stimulation, a homogeneous endometrial pattern on the day of hCG administration predicts a significantly decreased PR compared with a trilaminar pattern.PMID: 9240250, UI: 97384582 Summary Brief Abstract Citation MEDLINE ASN.1 XML/SGML LinkOut Related Articles Protein Links Nucleotide Links Popset Links Structure Links Genome Links OMIM Links Write to the Help Desk NCBI | NLM | NIH Department of Health & Human Services Freedom of Information Act | Disclaimer Quote Link to comment Share on other sites More sharing options...
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