Re: Endometrial biopsies/RU486

[Guest guest]

FYI In prepration for the J956 clinical trial,

I started the washout on my own and after 1 week off

b/c pills I am in pretty uncomfortable pain. The only thing

that gives me relief is tylenol 3 w/ codine. It makes you kind

of fuzzy but definately takes the edge off the pain. Point is

I couldn't have taken the pain for 2 or 3 months to get through

the wash out so... anyone considering the J956 trial, make sure

you are prepared for some discomfort when you go off the b/c

pills. Now I'm scheduled for UFE which was my next step after

the clinical trial anyhow. Can't wait to start back on the

b/c pills to get some relief. Oh well, at least now I'm forced

to take some action.

Regards,

Kim W Atlanta

> > Hi,

> >

> > I'm 's Mife-sister, Elise. made that moniker up hahaha!

> I'm

> > in the same Mifepristone study, but 4 1/2 months behind...

> >

> > I have been on the drug, aka ru486, for about 5 weeks now. I

don't

> > have any side effects except that I didn't get my period (gee, too

> > bad!).

> >

> > My only real complaint from the fibroids is urinary frequency - my

> > bladder never feels empty. Right after I urinate, within minutes,

> I

> > feel like I have to go again. Unfortunately, this has not resolved

> at

> > all yet, although I know it is still early. I am going back to

> > Rochester on June 19 for my second ultrasound exam.

> >

> > Like , if I do get results, I plan to submit to the

endometrial

> > biopsy (gulp!) and continue for an additional 6 months on the

drug,

> > which they have offered.

> >

> > I am a little concerned about the possible buildup of

endomitrium.

> I

> > have a lot of endometriosis in various places, like my ovaries,

> > although I don't have any symptoms. I am concerned that the

> > unopposed estrogen might cause a worsening of my endometriosis.

> > Although, you would think that unopposed estrogen would make the

> > fibroids worse! I don't get it!

> >

> > Anyway, I'll post my results after the next ultrasound.

> >

> > Good luck to all.

> >

> > Elise in NYC

> >

> >

> > > So far as I know, this study was the first to last so many

> months.

> > The

> > > previous trial was only 4 months. To go a year on the drug would

> > really be

> > > breaking new ground. I've been so pleased with the outcome so

> far,

> > I really

> > > hope to continue to see how much closer to normal size I can

get.

> > If I can't

> > > continue, well, I guess I'll find out first-hand if the fibroids

> > will regrow,

> > > and if so, how much will come back. At this point, I can't think

> > too far

> > > ahead. I have to take things as they happen.

> > >

> > > I hope this helps you.

> > >

> > >