Amphetamines such as benzedrine and dexedrine appears to be associated with an increased risk of Parkinson’s disease

February 22, 2011

Prior use of amphetamines such as benzedrine and dexedrine appears to be

associated with an increased risk of Parkinson's disease (PD), according to

research released Feb. 20 to be presented at the annual meeting of the

American Academy of Neurology, which will be held from April 9 to 16 in

Honolulu.

K. Van Den Eeden, Ph.D., of Kaiser Permanente Northern California in

Oakland, and colleagues evaluated 66,438 individuals who participated in the

Multiphasic Health Checkup Cohort Exam between 1964 and 1973. Participants

were asked whether they had used drugs for weight loss (drugs unspecified)

and whether they used benzedrine or dexedrine often. PD was diagnosed in

1,154 individuals.

The investigators found that those who reported taking weight loss

medication did not have an increased risk of PD. However, individuals who

reported using benzedrine or dexedrine were at increased risk of developing

PD (hazard ratio, 1.56).

" These prospective data suggest that amphetamines may increase the risk of

subsequent PD. This finding should be confirmed, and if true, would need to

be incorporated into amphetamine abuse programs, as well as clinical

judgments in use of amphetamines, " the authors write.

The study was funded by Kaiser Permanente Northern California.

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Ortiz, MS, RD

Check out my blog: mixture of deals and nutrition

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