Chemopreventive agents in black raspberries identified

[Guest guest]

Colleagues, the following is FYI and does not necessarily reflect my own

opinion. I have no further knowledge of the topic. If you do not wish to

receive these posts, set your email filter to filter out any messages

coming from @nutritionucanlivewith.com and the program will remove

anything coming from me.

---------------------------------------------------------

Public release date: 8-Jan-2009

http://www.eurekalert.org/pub_releases/2009-01/aafc-cai010609.php

Contact:

.moore@...

American Association for Cancer Research

Chemopreventive agents in black raspberries identified

PHILADELPHIA – A study published in Cancer Prevention Research, a

journal of the American Association for Cancer Research, identifies

components of black raspberries with chemopreventive potential.

Researchers at the Ohio State Comprehensive Cancer Center found that

anthocyanins, a class of flavonoids in black raspberries, inhibited

growth and stimulated apoptosis in the esophagus of rats treated with an

esophageal carcinogen.

" Our data provide strong evidence that anthocyanins are important for

cancer prevention, " said the study's lead author, D. Stoner, Ph.D.,

a professor in the department of internal medicine at Ohio State University.

Stoner and his team of researchers fed rats an anthocyanin-rich extract

of black raspberries and found that the extract was nearly as effective

in preventing esophageal cancer in rats as whole black raspberries

containing the same concentration of anthocyanins. This study

demonstrates the importance of anthocyanins as preventive agents in

black raspberries and validated similar in vitro findings. It is among

the first to look at the correlation between anthocyanins and cancer

prevention in vivo.

Stoner and his colleagues have conducted clinical trials using whole

berry powder, which has yielded some promising results, but required

patients to take up to 60 grams of powder a day. " Now that we know the

anthocyanins in berries are almost as active as whole berries

themselves, we hope to be able to prevent cancer in humans using a

standardized mixture of anthocyanins, " said Stoner.

" The goal is to potentially replace whole berry powder with its active

components and then figure out better ways to deliver these components

to tissues, to increase their uptake and effectiveness. Ultimately, we

hope to test the anthocyanins for effectiveness in multiple organ sites

in humans, " said Stoner.

--

ne Holden, MS, RD

" Ask the Parkinson Dietitian " http://www.parkinson.org/

" Eat well, stay well with Parkinson's disease "

" Parkinson's disease: Guidelines for Medical Nutrition Therapy "

http://www.nutritionucanlivewith.com/