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Cortisol and DHEA

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>>>snip

But some patients’ adrenal cortex cells don’t convert pregnenolone to

cortisol at a normal rate. As a result, the patients’ cortisol levels may

decrease. As Dr. Durrant-Peatfield writes, in these patients, the

pregnenolone that would have been converted to cortisol may instead be

converted to DHEA. This may raise the patients’ DHEA levels, and it may

increase the ratio of DHEA to cortisol. Researchers have found this

pattern—an increased ratio of DHEA to cortisol—in patients with panic

disorder.[2]

In summary, cells of the adrenal cortex may use less pregnenolone to produce

cortisol, and this may divert more pregnenolone into the pathway that leads

to DHEA. If so, lab tests may show a low ratio of cortisol to DHEA. This

does not mean, however, that DHEA has suppressed the cortisol level. As Dr.

Durrant-Peatfield suggests, it simply means that the cells of the adrenal

cortex have increased their production of DHEA at the expense of cortisol.

References

[1] Durrant-Peatfield, B.: The Great Thyroid Scandal and How to Survive It.

London, Barons Down Publishing,

from Dr. Lowe's website

http://www.drlowe.com/QandA/askdrlowe/mostrecent.htm

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  • 3 years later...

My Endro also suggested DHEA after my tests came back so low – I take 50

mg’s and have since early September – the biggest thing I have noticed is

that the horrible hip joint pain I have suffered with for 15 years is going

away.

I also had to cut my armour back, was having reactions. I have noticed my

hormones are a bit whacky, I got next week to get results from my blood

work, hope he tested those this time. I’m not sure what I should cut back

on in the hormone department – I tried to stop taking them, but that didn’t

work, so now I am just back to taking them every day.

The Endro had said that the DHEA would help with the adrenals in a natural

way, make them work on their own instead of just giving them HC, he said it

would also help the hypothalamus and thalamus and thyroid in a trickle down

effect over time.

Good luck.

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