Re: Re: Andy: why does ALA cross the BBB?

[Guest guest]

I thought I might simplify this even more for others who dont understand the

chemist jargon

andrewhallcutler wrote:

>

> > To Andy (or anyone else who is up to chemical explanations):

> >

> > I'm wondering what it is about the BBB and about ALA that

> > makes it such that ALA crosses the BBB (and other chelators

> > don't).

>

> It is well known for all classes of drugs.

>

> Lipophilic

Lipophilic - lipo (fat) philic (liking or having a strong affinity or

preference for; loving:)

> things cross the BBB readily.

>

> Hydrophilic

Hydro (water) philic (liking)

> (lipophobic)

lipo (fat) phobic (lacking an affinity for)