(was) Vaccines (now) worry of family having MS too and probabilities

[Guest guest]

Hi All:

So Darlene and I are "twins". Both of us had flu shots in 95 and it awakened a MonSter inside of us. Sounds like something from Sci-Fi Theater, doesn't it? I'm sorry to hear about your daughter, Darlene. What kind of symptoms is she having? As you know my daughter (Challis) has plenty of symptoms, but no dx yet. I would like her to have another MRI. Maybe she will see a new neuro soon. (hint, hint).

My son is 34 and he also has symptoms. He works out in the heat here in Arizona but has been on a big job recently where he had to spend long days out in the heat instead of just working the cooler morning hours. Our temps have been anywhere from 105 to 118. His feet started bothering him and they have been itching horribly and both feet are numb. That's been going on for a week now. He's very fatigued--more so than you would expect from hard physical labor in the sun.

How much do we all worry about our children and grandchildren having MS or another neurological disorder? In this household I have an 8 y/o granddaughter a who falls down a lot and loses her balance, another one (10 y/o) who complains of 'funny feelings' in her legs and an 11 y/o grandson who worries he has MS because his back aches. I had symptoms when I was a child so it's not out of the realm of possibilities.

I don't know what the experts now say the probabilities are of having family members with MS. But I've spoken with a lot of MSers who have a mother, child or sister with MS. I have a childhood friend who has MS and his brother had Guillain-Barré Syndrome, a very close 'relative' of MS. Years ago I started a local support group. There were 3 mother/daughter members and one who's grandfather had MS. This was in a group of only 12-15 members. I think that's pretty high stats.

What do you all think?

Sharon

Vaccines cited as cause of neurological disorder

This is info on cases of Transverse Myelitis from Vaccines & Immunizations. (TM is often a precursor to an MS diagnosis):

http://www.whale. to/vaccines/ transverse. html

Larner AJ, Farmer SF. Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression. Eur J Neurol. 2000 Nov;7(6):731- 3. PMID: 11136365 [PubMed - indexed for MEDLINE]We report a patient who developed a transverse myelitis with Brown-Sequard syndrome following a prophylactic influenza vaccination, despite being chronically immunosuppressed for a steroid-responsive optic neuropathy. Although influenza vaccination is recommended in patients receiving chronic immunosuppression, its use may on occasion be associated with neurological

complications previously reported in immunocompetent individuals.

Transverse myelitis & vaccine citationsNervous system

[Media July 2006] Legal aid victory for paralysed MMR boy

News: Roadblocks frustrate Little Al (hep B reaction)

Dr. . A neurologist and assistant professor at Harvard Medical School, had been retained to testify for people with transverse myelitis, a potentially paralyzing neurological disorder. said he was "highly confident" that the tetanus vaccine could trigger the ailment in certain vulnerable individuals. Officials with the Vaccine Injury Compensation Program strongly disagreed. Then quit. According to court papers and interviews, decided to bail out after complaints were lodged with his superiors by three other experts with a long history of testifying for the government in vaccine court.....Early in 2002, was informed (that he) "was ruining his reputation by his testimony in the vaccine program," ...Wary of

antagonizing people who could affect his career, decided to drop out after testifying in one last case, ..... was told in so many words that he was jeopardizing his access to research funding. [Media, 29 Nov 2004] Witnesses for Petitioners Are Often Tough to Find

Abdennebi A, Dumas JL, Salama J, Benromdhane H, Belin C, Goldlust D. [Postvaccination myelitis. Aspect and course followed by MRI]J Radiol. 1996 May;77(5):363- 6. French.PMID: 8762935 [PubMed - indexed for MEDLINE]

Fescharek R, et al (1995) Transverse myelitis unlikely to be due to measles, mumps, and rubella vaccine. BMJ. 1995 Dec 16;311(7020) :1642. No abstract available. PMID: 8555831; UI: 96111884.

Granata F, et al. [Case of transverse myelitis induced by anticholera vaccination] . Acta Neurol (Napoli). 1974 Sep-Oct;29(5) :511-5. Italian. No abstract available.PMID: 4451167; UI: 75106160

Joyce KA, et al. Transverse myelitis after measles, mumps, and rubella vaccine. BMJ. 1995 Aug 12;311(7002) :422. No abstract available.PMID: 7640590; UI: 95367940.

Karaali-Savrun F, Altintas A, Saip S, Siva A. Hepatitis B vaccine related-myelitis? Eur J Neurol. 2001 Nov;8(6):711- 5.PMID: 11784358 [PubMed - indexed for MEDLINE]

Larner AJ, Farmer SF. Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression. Eur J Neurol. 2000 Nov;7(6):731- 3. PMID: 11136365 [PubMed - indexed for MEDLINE]We report a patient who developed a transverse myelitis with Brown-Sequard syndrome following a prophylactic influenza vaccination, despite being chronically immunosuppressed for a steroid-responsive optic neuropathy. Although influenza vaccination is recommended in patients receiving chronic immunosuppression, its use may on occasion be associated with neurological complications previously reported in immunocompetent individuals.Renard JL, Guillamo JS, Ramir! ez JM, Taillia H, Felten D, Buisson Y. Presse Med 1999 Jul 3-10;28(24): 1290-2 [No title available].[ Article in French] Clinique de neurologie, HIA Val-de-Grace, Paris. [Medline record in process]BACKGROUND: The cause and effect relationship between anti-HBV immunization using recombinant vaccine and the development of a neurological event, including flare-ups of multiple sclerosis, is a widely debated issue.CASE REPORT: A previously asymptomatic 16-year-old girl was a hyper-responder to anti-HBV vaccine. Subsequent to a booster shot of anti-HBV recombinant vaccine, she developed regressive acute cervical transverse myelitis with intrathecal oligochonal IgG secretion and a hypersignal on the MRI T2 sequences of the cord.DISCUSSION: The distinction between a first episode of multiple sclerosis or post-vaccinal acute myelitis in this case will depend upon subsequent course, but this

observation points out the very high level of persistent post-vaccinal immunizat! ion which can be acquired by a hyper-responder. PMID: 10442059, UI: 99370647

Tezzon F, Tomelleri P, Ferrari G, Sergi A. Acute radiculomyelitis after antitetanus vaccination. Ital J Neurol Sci. 1994 May;15(4):191- 3. Review.PMID: 7960672 [PubMed - indexed for MEDLINE]We report the assessment by MRI of a case of radiculomyelitis after vaccination against tetanus-poliomyelit is. In the acute stage the appearance was an isolated myelitis of the conus medullaris with contrast enhancement. The upper thoracic cord presented central areas of high signal intensity on T2 weighted images. Rapid clinical recovery was correlated with resolution of abnormal enhancement. Follow-up MR at 5 months showed persistence of slight T2 prolongation in the conus medullaris and syringohydromyela of the thoracic cord. A single lesion of the spinal cord is a rare

presentation of acute disseminated en! cephalomyelitis, the course of such lesions, to date not previously displayed by MR, is unknown. Proper diagnosis should help prevent administration of further vaccine doses.

Sharon (MSersLife Group Owner/Creator)

Kind words may be short... but their echoes are endless.... Mother Theresa

[Guest guest]

I'm in the same club but I joined a few years later!

I am just hoping and praying that Robbin doesn't have any of this, he has enough to deal with as it is. I know that he did inherit his body type from his Dad, Thank God/dess!!! I would Hate for him to have to go through life with the same body issues I have had to deal with. SO I am hoping maybe he also got his Father's good health and constitution.

Peace and Blessings

~*~ Akiba ~*~

Pragmatic Visionary

http://yodamamma.blogspot.com/

http://www.solay-twinflames.com

-- (was) Vaccines (now) worry of family having MS too and probabilities

Hi All:

So Darlene and I are "twins". Both of us had flu shots in 95 and it awakened a MonSter inside of us. Sounds like something from Sci-Fi Theater, doesn't it? I'm sorry to hear about your daughter, Darlene. What kind of symptoms is she having? As you know my daughter (Challis) has plenty of symptoms, but no dx yet. I would like her to have another MRI. Maybe she will see a new neuro soon. (hint, hint).

My son is 34 and he also has symptoms. He works out in the heat here in Arizona but has been on a big job recently where he had to spend long days out in the heat instead of just working the cooler morning hours. Our temps have been anywhere from 105 to 118. His feet started bothering him and they have been itching horribly and both feet are numb. That's been going on for a week now. He's very fatigued--more so than you would expect from hard physical labor in the sun.

How much do we all worry about our children and grandchildren having MS or another neurological disorder? In this household I have an 8 y/o granddaughter a who falls down a lot and loses her balance, another one (10 y/o) who complains of 'funny feelings' in her legs and an 11 y/o grandson who worries he has MS because his back aches. I had symptoms when I was a child so it's not out of the realm of possibilities.

I don't know what the experts now say the probabilities are of having family members with MS. But I've spoken with a lot of MSers who have a mother, child or sister with MS. I have a childhood friend who has MS and his brother had Guillain-Barré Syndrome, a very close 'relative' of MS. Years ago I started a local support group. There were 3 mother/daughter members and one who's grandfather had MS. This was in a group of only 12-15 members. I think that's pretty high stats.

What do you all think?

Sharon

Vaccines cited as cause of neurological disorder

This is info on cases of Transverse Myelitis from Vaccines & Immunizations. (TM is often a precursor to an MS diagnosis):

http://www.whale. to/vaccines/ transverse. html

Larner AJ, Farmer SF. Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression. Eur J Neurol. 2000 Nov;7(6):731- 3. PMID: 11136365 [PubMed - indexed for MEDLINE]We report a patient who developed a transverse myelitis with Brown-Sequard syndrome following a prophylactic influenza vaccination, despite being chronically immunosuppressed for a steroid-responsive optic neuropathy. Although influenza vaccination is recommended in patients receiving chronic immunosuppression, its use may on occasion be associated with neurological complications previously reported in immunocompetent individuals.

Transverse myelitis & vaccine citationsNervous system

[Media July 2006] Legal aid victory for paralysed MMR boy

News: Roadblocks frustrate Little Al (hep B reaction)

Dr. . A neurologist and assistant professor at Harvard Medical School, had been retained to testify for people with transverse myelitis, a potentially paralyzing neurological disorder. said he was "highly confident" that the tetanus vaccine could trigger the ailment in certain vulnerable individuals. Officials with the Vaccine Injury Compensation Program strongly disagreed. Then quit. According to court papers and interviews, decided to bail out after complaints were lodged with his superiors by three other experts with a long history of testifying for the government in vaccine court.....Early in 2002, was informed (that he) "was ruining his reputation by his testimony in the vaccine program," ...Wary of antagonizing people who could affect his career, decided to drop out after testifying in one last case, ..... was told in so many words that he was jeopardizing his access to research funding. [Media, 29 Nov 2004] Witnesses for Petitioners Are Often Tough to Find

Abdennebi A, Dumas JL, Salama J, Benromdhane H, Belin C, Goldlust D. [Postvaccination myelitis. Aspect and course followed by MRI]J Radiol. 1996 May;77(5):363- 6. French.PMID: 8762935 [PubMed - indexed for MEDLINE]

Fescharek R, et al (1995) Transverse myelitis unlikely to be due to measles, mumps, and rubella vaccine. BMJ. 1995 Dec 16;311(7020) :1642. No abstract available. PMID: 8555831; UI: 96111884.

Granata F, et al. [Case of transverse myelitis induced by anticholera vaccination] . Acta Neurol (Napoli). 1974 Sep-Oct;29(5) :511-5. Italian. No abstract available.PMID: 4451167; UI: 75106160

Joyce KA, et al. Transverse myelitis after measles, mumps, and rubella vaccine. BMJ. 1995 Aug 12;311(7002) :422. No abstract available.PMID: 7640590; UI: 95367940.

Karaali-Savrun F, Altintas A, Saip S, Siva A. Hepatitis B vaccine related-myelitis? Eur J Neurol. 2001 Nov;8(6):711- 5.PMID: 11784358 [PubMed - indexed for MEDLINE]

Larner AJ, Farmer SF. Myelopathy following influenza vaccination in inflammatory CNS disorder treated with chronic immunosuppression. Eur J Neurol. 2000 Nov;7(6):731- 3. PMID: 11136365 [PubMed - indexed for MEDLINE]We report a patient who developed a transverse myelitis with Brown-Sequard syndrome following a prophylactic influenza vaccination, despite being chronically immunosuppressed for a steroid-responsive optic neuropathy. Although influenza vaccination is recommended in patients receiving chronic immunosuppression, its use may on occasion be associated with neurological complications previously reported in immunocompetent individuals.Renard JL, Guillamo JS, Ramir! ez JM, Taillia H, Felten D, Buisson Y. Presse Med 1999 Jul 3-10;28(24): 1290-2 [No title available].[ Article in French] Clinique de neurologie, HIA Val-de-Grace, Paris. [Medline record in process]BACKGROUND: The cause and effect relationship between anti-HBV immunization using recombinant vaccine and the development of a neurological event, including flare-ups of multiple sclerosis, is a widely debated issue.CASE REPORT: A previously asymptomatic 16-year-old girl was a hyper-responder to anti-HBV vaccine. Subsequent to a booster shot of anti-HBV recombinant vaccine, she developed regressive acute cervical transverse myelitis with intrathecal oligochonal IgG secretion and a hypersignal on the MRI T2 sequences of the cord.DISCUSSION: The distinction between a first episode of multiple sclerosis or post-vaccinal acute myelitis in this case will depend upon subsequent course, but this observation points out the very high level of persistent post-vaccinal immunizat! ion which can be acquired by a hyper-responder. PMID: 10442059, UI: 99370647

Tezzon F, Tomelleri P, Ferrari G, Sergi A. Acute radiculomyelitis after antitetanus vaccination. Ital J Neurol Sci. 1994 May;15(4):191- 3. Review.PMID: 7960672 [PubMed - indexed for MEDLINE]We report the assessment by MRI of a case of radiculomyelitis after vaccination against tetanus-poliomyelit is. In the acute stage the appearance was an isolated myelitis of the conus medullaris with contrast enhancement. The upper thoracic cord presented central areas of high signal intensity on T2 weighted images. Rapid clinical recovery was correlated with resolution of abnormal enhancement. Follow-up MR at 5 months showed persistence of slight T2 prolongation in the conus medullaris and syringohydromyela of the thoracic cord. A single lesion of the spinal cord is a rare presentation of acute disseminated en! cephalomyelitis, the course of such lesions, to date not previously displayed by MR, is unknown. Proper diagnosis should help prevent administration of further vaccine doses.

Sharon (MSersLife Group Owner/Creator)

Kind words may be short... but their echoes are endless.... Mother Theresa