Re: Serrapeptase--Enteric Coating Dangerous?

[Guest guest]

This is a confusing topic, as my understanding is that phthalates can

raise estrogen, and estrogen dominance is a problem today. Maca

reportedly raises estrogen also, although it also raises progesterone.

In the case of uterine fibroids, estrogen dominance is one of the

factors, so if Maca raised the estrogen even higher that could be a

problem. Yet, I have also read that Maca is helpful for uterine

fibroids.

[Guest guest]

Hi ,

Can you provide the name or a link to the place where you purchase the

Maca?

Thanks

>

> It is my understanding that it balances hormones. I love it for

several reasons. It's a raw food, not a drug, it helps with thyroid

problems, it helps with circulation. Maca does not contain hormones

itself. Instead it provides a unique set of nutrients that directly

[Guest guest]

I can't remember what specifically it is, but I have read several times

about a remedy to the fibroids. I think there is a few different remedies for

them. I would try googling some info on it. There is probably many different

ways to rid them.

Heidi N

" In the case of uterine fibroids, estrogen dominance is one of the

factors, so if Maca raised the estrogen even higher that could be a

problem. Yet, I have also read that Maca is helpful for uterine

fibroids. "

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[Guest guest]

I asked the Good Health Naturally Company for info about the safety

of the phthalates in the HPMCP (enteric coating). The following is

the response I got. I am concerned about the response that " Rats

survived daily feedings of up to 30 in the diet for up to one year

without showing a depression in growth. " (see below).

Here is some information and studies that we have on Phthalates

in the HPMCP. If you have any more questions please let us know.

Cellulose acetate phthalate is widely used in oral pharmaceutical

products and is generally regarded as a nontoxic material, free of

adverse effects.

Results of long-term feeding studies with cellulose acetate

phthalate, in rats and dogs, have indicated a low oral toxicity. Rats

survived daily feedings of up to 30 in the diet for up to one year

without showing a depression in growth. Dogs fed 16 g daily in the

diet for one year also remained normal (Hodge, H. C., " The Chronic

Toxicity of Cellulose Acetate Phthalate in Rats and Dogs " , J.

Pharmacol., 80, 250-255, (1944)).

Safety:

Hydroxypropylmethylcellulose phthalate (HPMCP) has been heretofore

widely used, primarily as an enteric coating agent, in oral

pharmaceutical formulations. Chronic and acute animal feeding studies

on several different species have shown no evidence or teratogenicity

or toxicity associated with hydroxypropylmethylcellulose phthalate

(Kitagawa, H., Kawana, H., Satoh, T., Fukuda, Y., " Acute and Subacute

Toxicities of Hydroxypropyl Methylcellulose Phthalate " ,

Pharmacometrics, (1970), 4(6):1017-1025; Kitagawa, H., Satoh, T.,

Yokoshima, T., Nanbo, T., " Absorption, Distribution and Excretion of

Hydroxypropyl Methylcellulose Phthalate in the Rat " , Pharmacometrics,

(1971), 5(1):1-4; Ito, R., Toida, S., " Studies on the Teratogenicity

of a New Enteric Coating Material, Hydroxypropyl Methylcellulose

Phthalate (HPMCP) in Rats and Mice " , J. Med. Soc. Toho-Univ., (1972),

19(5):453-461; Kitagawa, H., Yano, H., Fukuda, Y., " Chronic Toxicity

of Hydroxypropylmethylcellulose Phthalate in Rats " , Pharmacometrics,

(1973), 7(5);689-701; Kitagawa, H., Yokoshima, T., Nanbo, T.,

Hasegawa, M., " Absorption, Distribution, Excretion and Metabolism of

14 C-hydroxypropyl Methylcellulose Phthalate " , Pharmacometrics,

(1974), 8(8):1123-1132. Hydroxypropylmethylcellulose phthalate is

generally regarded as a nonirritant and nontoxic material.

LD50 (rat, oral): >15 g/kg (Kitagawa et al., Pharmacometrics, (1970),

4(6):1017-1025).

Regulatory Status: included in the FDA Inactive Ingredients Guide

(oral capsules and tablets) and included in nonparenteral medicines

licensed in the United Kingdom.

Pharmacopeias: Br, Eur, Fr, Gr, It, Jpn, Neth, Port, Swiss and USPNF.

Related Substances: cellulose acetate phthalate; Hydroxypropyl-

Methylcellulose.

Regulatory Status:

Included in the FDA Inactive Ingredients Guide (oral capsules and

tablets). Included in nonparenteral medicines licensed in the United

Kingdom.

Pharmacopeias: Aust, Br, Braz, Cz, Eur, Fr, Ger, Gr, Hung, Ind, It,

Jon, Mex, Neth, Nord, Port, Swiss and USPNF.

Some of the properties of HPMCP, described in the Handbook of

Pharmaceutical Excipients are summarized as follows:

Non proprietary Names: BP: Hypromellose phthalate; PhEur:

Methylhydroxypropylcellulosi phthalas and USPNF: Hydroxypropyl-

methylcellulose phthalate.

Synonyms: Cellulose phthalate hydroxypropyl methyl ether; HPMCP; 2-

hydroxypropylmethylcellulose phthalate; methylhydroxypropylcellulose

phthalate.

Chemical Name and CAS Registry Number: Cellulose, hydrogen 1,2-

benzenedicarboxylate, 2-hydroxypropyl methyl ether [9050-31-1]

Functional Category: Coating Agent.

Applications in Pharmaceutical Formulations or Technology

Best Regards,

Good Health Naturally

www.GoodHealthUSA.com

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