Re: ARNE/BARBARA UK/OFF TOPIC

[Guest guest]

If I could grow another liver, even with the possibility of PSC recurrence, I'd still take it. There would be no immune response, since it's "mine". This would remove a significant complication of transplantation.

Hi Arne,

I think I would rather have my own new liver than someone elses and with a bit of luck it'll give me some years of good health. Maybe by then they'll be able to effect a cure or maybe know how to stop it coming in the first place.

Barbara (UK)

[Guest guest]



If we were to

clone organs – couldn’t use our own DNA as it would include the PSC & IBD.

How would “theyâ€

know for sure that the DNA of another person wouldn’t also have defective or

recessive genes - that had not shown up yet? 

Aren’t there too many unknowns?  If

they could filter out the bad genes wouldn’t that mean they had found the genes

responsible and if so cure us?  Man this

is all so complicated. Easy to understand how people can come down on different

sides of this issue.    

Barb in

Texas

Son, Ken 28

UC 91 PSC 99

-----Original

Message-----

From: A & J Myrabo

In my opinion, if we

could clone organs (without an attached body), it would solve many of our

problems. This has been the topic of innumerable science fiction stories.

 

[Guest guest]



-----Original Message-----From: Barb Henshaw

....If we were to clone organs – couldn’t use our own DNA as it would include the PSC & IBD.

I would, as I would be able to avoid an immune response to transplantation. Granted, it may only buy me another 5-10-40 years (who knows).

... How would “they†know for sure that the DNA of another person wouldn’t also have defective or recessive genes - that had not shown up yet? Aren’t there too many unknowns?

You wouldn't (yet, but it's coming) - it's the same issue with current transplants, cadaveric or living.

... If they could filter out the bad genes wouldn’t that mean they had found the genes responsible and if so cure us?

Exactly - and Dr. McCoy's little scanner would have arrived. This is ultimately the solution.

If I could grow another liver, even with the possibility of PSC recurrence, I'd still take it. There would be no immune response, since it's "mine". This would remove a significant complication of transplantation.

Arne51 - UC 1977 - PSC 2000Alive and (mostly) well in Minnesota

Man this is all so complicated. Easy to understand how people can come down on different sides of this issue.

Barb in Texas

Son, Ken 28

UC 91 PSC 99

[Guest guest]

RE:

ARNE/BARBARA UK/OFF TOPIC

-----Original Message-----

From: Barb Henshaw

....If we

were to clone organs – couldn’t use our own DNA as it would include

the PSC & IBD.

I would, as I would be able to avoid an immune response to

transplantation. Granted, it may only buy me another 5-10-40 years (who knows).

... How would “they” know for

sure that the DNA of another person wouldn’t also have defective or

recessive genes - that had not shown up yet? Aren’t there too many

unknowns?

You wouldn't (yet, but

it's coming) - it's the same issue with current transplants, cadaveric or

living.

... If they could filter out the bad genes

wouldn’t that mean they had found the genes responsible and if so cure

us?

Exactly - and Dr.

McCoy's little scanner would have arrived.

This is ultimately the solution.

If I could grow another liver, even with the possibility of PSC

recurrence, I'd still take it.

There would be no immune response, since it's " mine " . This would remove a significant

complication of transplantation.

Yep! And you would still be better off

than the 15 – 25% of us who experience recurrent PSC in the graft, and DO

have to worry about an immune response. As I’ve said before, ESLD brings

you to the old Transplantation Two-step: “Do you want Garbage, or Trash –

Do you want a 100% chance that you’ll die without the transplant, or an

85% chance to survive one year with the transplant”

Arne

51 - UC 1977 - PSC 2000

Alive and (mostly) well in Minnesota

Steve Rahn

L Tx

9/85; Waiting for Re-Tx

" Face

the Worst, Expect the Best,

Do

the Most, Forget the Rest "