Re: percent of renal function

[Guest guest]

denise ,,,,what is that web site you used to look up your renal

function?,,,,,,,crystal,,south carolina

[Guest guest]

Crystal,

The site is www.kidney.org ---------gfr calculator.

> denise ,,,,what is that web site you used to look up your renal

> function?,,,,,,,crystal,,south carolina

>

>

>

[Guest guest]

Hi ,

You know, my doctor never does test for BUN, so I am not much help on this

one.

Sorry.

[Guest guest]

Bun (or simply urea) is a very variable thing . It can go up or down in

response to your level of hydration and what you eat, notably. However, yes,

generally, as IgAN advances, urea tends to increase. Urea is one of the main

things that diseased kidneys can't remove very well.

A dropping serum albumin is usually not a good thing to have. Ask your

doctor, but, a below normal albumin is often a sign of eating too little

protein. If that happens, and it isn't corrected by diet, the body begins to

cannibalise its own muscle tissue for energy - ie. malnutrition. I'm not

saying that this is the case here, but it could be. Albumin is a form of

protein we have in our bloodstream. What also happens is that initially,

serum creatinine may go down also, because you have less muscle mass

producing it - but that's not a good sign, even though it appears better.

Pierre

Re: percent of renal function

> Hi all

> I know this is a little late on the thread but that's the drawback of

> working away! Having played with the GFR calculator it does put alot of

> emphysis on both the BUN and S albumin figures, an SA value of 0 gives a

GFR

> of 0 for example, its about the only part of the blood test that going

down

> is bad!! This leads me to beg the question, how common is it out there in

> iganland to find a good (and static) Cr level at 106 (UK Connie;) ) but a

> consistantly rising, over 4 tests and now rated as high, BUN and a

> consistantly dropping SA, now rated as low? Does it mean that where bun/sa

> goes, cr is sure to follow, or the alternative that esrd can occur from a

> divergent bun/sa??

> If you get no replies instantly its because I'm not here rather than being

> rude, but then again I might be!!!

> 'Dubbya'

[Guest guest]

Pierre,

It's been along time since we last wrote. However, I read every email with

interest. Please read the following news article.

I had the same symptons listed below yet the Renal team also diagnosed me

with IgaN. I thought this would interest you as I played Rugby as well.

I had the opportunity to watch Nick play for his club side Harlequins and

witnessed the new phenomenon which would grace our " respected " national

sport.

I find it very upsetting to realise that even those who are physically and

mentally strong are at the hands of someone, something?

Am I the only person with this connection?

Regards

Ian

Nick Duncombe, the talented 21-year-old England rugby international, died of

heart failure due to sepsis, according to the doctors who treated him in

Lanzarote. The Harlequins player was training in the Canary Islands when he

was taken ill, and within 24 hours of complaining of a sore throat, he was

dead.

Sepsis is a general medical term for the body's response to an overwhelming

bacterial infection, whatever that infection may be.

Although everybody is at potential risk of developing sepsis from minor

infections such as influenza or gastroenteritis, it is most likely to

develop in the very old or very young or those with compromised immune

systems. It is rare for someone as young and fit as Nick Duncombe to

succumb.

Sepsis kills about 75,000 people in Britain every year, and is marked by

fever, nausea, shivering and disorientation. Septic shock is a serious form

of the condition, when the blood pressure plummets. Even with expert care,

half of all such patients die because of multiple organ failure.

Although the exact cause of death remains a mystery, it seems likely that

Nick Duncombe contracted a type of sepsis known as meningococcal

septicaemia, a deadly form of blood poisoning.

Although this is rare, killing 846 people in England and Wales in 2002, it

is indiscriminate and kills extremely quickly. The athlete reportedly

developed a purple rash all over his body, which is typical of this type of

infection.

" Meningococcal septicaemia affects the young and fit, too, " says

Booker, research co-ordinator of the National Meningitis Trust. " It makes no

difference if someone has a sturdy immune system. "

Sepsis can also be caused by different organisms that invade the body and

proliferate in just a few days. The vast majority of bloodstream infections,

known as septicaemia, are caused by the staphylococcus aureus bacterium

which is normally found on the skin.

A flesh wound can allow the organism to gain access to the circulatory

system. Dr Shanson, a microbiologist, points out that most of the

12,000 cases reported each year occur in hospitals, " because this is where

vulnerable people tend to be. Cases in the community are few and far

between. "

Occasionally, women who are menstruating and using tampons suffer toxic

shock syndrome caused by staphylococcal bacteria in the vagina.

Almost as prevalent is sepsis caused by the E. coli bug, which lives in the

gut. In rare cases, it passes through the intestinal wall into the

bloodstream. The particularly nasty strain, E. coli 0157, is a form of food

poisoning. Lethal to vulnerable people, it is found on contaminated meat.

Meningococcal and streptococcal bacteria, which normally live harmlessly in

the human nose and throat, can also get into the bloodstream, causing

sepsis. Many of these bacteria produce powerful toxins which destroy cells

and capillaries, causing massive internal bleeding and septic shock.

Pneumococcal bacteria can also lead to sepsis. These organisms, which

usually cause no problem, are the most common bacteria found in the blood of

children under two with fevers, many of whom have no obvious site of

infection.

Smokers are more likely to carry the fatal meningococcal bacteria. The

Meningitis C vaccination, introduced in 1999, has cut the overall number of

fatalities. In the end, however, there is no substitute for being observant.

" Just be aware of the medical symptoms and seek medical help as a matter of

urgency, " says Booker. " A sore throat accompanied by a livid rash

should always be a matter for concern. "

A timely dose of powerful antibiotics, if administered early, can reverse

the symptoms of sepsis.

Re: percent of renal function

>

>

> > Hi all

> > I know this is a little late on the thread but that's the drawback of

> > working away! Having played with the GFR calculator it does put alot of

> > emphysis on both the BUN and S albumin figures, an SA value of 0 gives a

> GFR

> > of 0 for example, its about the only part of the blood test that going

> down

> > is bad!! This leads me to beg the question, how common is it out there

in

> > iganland to find a good (and static) Cr level at 106 (UK Connie;) ) but

a

> > consistantly rising, over 4 tests and now rated as high, BUN and a

> > consistantly dropping SA, now rated as low? Does it mean that where

bun/sa

> > goes, cr is sure to follow, or the alternative that esrd can occur from

a

> > divergent bun/sa??

> > If you get no replies instantly its because I'm not here rather than

being

> > rude, but then again I might be!!!

> > 'Dubbya'

>

>

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>

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