Guest guest Posted December 28, 2002 Report Share Posted December 28, 2002 Thanks Barb, I was about to post a “never mind, I found the answer” – finally found a reference that answered my question – but you confirmed it. Once you understand it, it’s kind of a “duh-h-h” for someone who’s diagnosed with PSC, isn’t it? Steve Rahn L Tx 9/6 & 9/8 '85, Waiting for Re-Tx The Senility Prayer God grant me the senility to forget the people I never liked anyway, the good fortune to run into the ones that I do, and the eyesight to tell the difference " STEVE Hope this might help……. Alkaline phosphatase is an enzyme, or more precisely a family of related enzymes, produced in the bile ducts, intestine, kidney, placenta and bone. An elevation in the level of serum alkaline phosphatase (actually enzyme activity is measured in the clinical laboratory), especially in the setting of normal or only modestly elevated ALT and AST activities, suggests disease of the bile ducts. Serum alkaline phosphatase activity can be markedly elevated in bile duct obstruction or in bile duct diseases such as primary biliary cirrhosis or primary sclerosing cholangitis. Alkaline phosphatase is also produced in bone and blood activity can also be increased in some bone disorders. Barb in Texas Son, Ken 28 UC 91 PSC 99 -----Original Message----- From: Steve my quandary was why the Alk Phos is proportionally so much higher above the normal range than the AST and ALT. Quote Link to comment Share on other sites More sharing options...
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