Guest guest Posted February 21, 2007 Report Share Posted February 21, 2007 Hi Rita, If a prostate gland is removed, there should be no measurable PSA. Where there is a measurable PSA it means that the disease escaped the gland before the surgery, as you knew anyway from your previous posting and as predicted by your father’s diagnostic numbers. The radiotherapy is suggested in cases like this because, if the disease has not metastasized to remote parts of the body but is merely in the prostate bed, the radiation may be effective in dealing with these escaped cells. The ADT (Androgen Deprivation Therapy) – what you refer to as hormone – is given to deal with a metastasized disease, but generally speaking this therapy cannot cure the disease, merely manage it – often for many years. So what the doctors are suggesting is that they zap any diseased cells that may be close to where the gland was but at the same time deal with any that have spread further. All the best, Terry Herbert in Melbourne, Australia Diagnosed ‘96: Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. February '07 PSA 30.4 My site is at www.yananow.net As a physician, I am painfully aware that most of the decisions we make with regard to prostate cancer are made with inadequate data: Dr “Snuffy” Myers. From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of Rita Sent: Thursday, 22 February 2007 12:35 PM To: ProstateCancerSupport Subject: Post RP Update #2 - BAD NEWS My father just got his PSA result (done one month after RP) = 1.2 . The doc is really disappointed. He says it should have been = 0 . What does this mean ??? He's now telling my dad he has to do radiotherapy + hormono (Casodex 50mg/day for 1 month + Zoladex 10.8 mg/3 months for 3 years minimum). HOLY COW !!! I don't understand WHY he suggests the radio (please read last update below). Rita. > > Well, we got the results post RP (prostate + lymph node analysed) > and we're pretty disappointed but not surprised : > > My father's Gleason was upgraded to a 9 (instead of an 8). The > urologist analysed a lymph node (ganglion) and he found micro-mets > in the sample. You guys/gals were right : The cancer has escaped the > prostate (but it didn't show up on any tests : bone scan, taco, > etc.) ... Too small. > > The urologist said it's the first time in 25 years he's seen > this ... I find that hard to believe. He wants to consult the other > urologist to see what should be our next BEST step (either external > radiation, hormonotherapy, etc.). > > I really need your imput ... > > What do you all think ? If there are micro-mets in a lymph node, > there's a chance that there may be some more elsewhere. The doc is > telling us that hormonotherapy has a lot of side effects (what are > they?) and of course I don't trust external radiation at this point > because I'm afraid there are mets elsewhere. What else should we be > looking at ? He's only 63 years old. Do you all think his life is in > danger ? I'm thinking that hormonotherapy is probably the best thing > considering the situation. > > > Rita xxx. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 21, 2007 Report Share Posted February 21, 2007 Hi Rita, So sorry about your dad. By all means, he should see a good oncologist who specializes in prostate cancer. Where do you live? Dr. Bob Liebowitz in Los Angeles has had some very good success by placing his patients on complete hormone ablation for one year, the let them go off therapy, except for Proscar or Avodart maintenance. The PSA is closely monitored and if it rises, then go back on treatment. This is called Intermittent therapy. It seems to work well for many men. I wish you all the bestAubrey Pilgrim, DC (Ret.) Author ofA Revolutionary Approach to Prostate Cancer-Read the original book for FREE at: http://www.prostatepointers.org/prostate/lay/apilgrim/Read new edition for FREE at http://www.cancer.prostate-help.org/capilgr.htmDr. E. Crawford is co-author of the revision My father just got his PSA result (done one month after RP) = 1.2 . The doc is really disappointed. He says it should have been = 0 . What does this mean ??? He's now telling my dad he has to do radiotherapy + hormono (Casodex 50mg/day for 1 month + Zoladex 10.8 mg/3 months for 3 years minimum). HOLY COW !!! I don't understand WHY he suggests the radio (please read last update below).Rita. AOL now offers free email to everyone. Find out more about what's free from AOL at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Hi Rita, An oncologist usually specializes in cancer therapy using drugs and chemo. Urologists are often surgeons who specialize in diseases of the kidneys, bladder and urine systems- However, many of them do practice giving drugs and chemotherapy. I wish you all the bestAubrey Pilgrim, DC (Ret.) Author ofA Revolutionary Approach to Prostate Cancer-Read the original book for FREE at: http://www.prostatepointers.org/prostate/lay/apilgrim/Read new edition for FREE at http://www.cancer.prostate-help.org/capilgr.htmDr. E. Crawford is co-author of the revision In Quebec. What's the difference between oncologist and urologist ?Rita. AOL now offers free email to everyone. Find out more about what's free from AOL at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Can ADT cure some people ? Do some cancer cells die after ADT ? Rita. > > > > Well, we got the results post RP (prostate + lymph node analysed) > > and we're pretty disappointed but not surprised : > > > > My father's Gleason was upgraded to a 9 (instead of an 8). The > > urologist analysed a lymph node (ganglion) and he found micro- mets > > in the sample. You guys/gals were right : The cancer has escaped > the > > prostate (but it didn't show up on any tests : bone scan, taco, > > etc.) ... Too small. > > > > The urologist said it's the first time in 25 years he's seen > > this ... I find that hard to believe. He wants to consult the > other > > urologist to see what should be our next BEST step (either > external > > radiation, hormonotherapy, etc.). > > > > I really need your imput ... > > > > What do you all think ? If there are micro-mets in a lymph node, > > there's a chance that there may be some more elsewhere. The doc is > > telling us that hormonotherapy has a lot of side effects (what are > > they?) and of course I don't trust external radiation at this > point > > because I'm afraid there are mets elsewhere. What else should we > be > > looking at ? He's only 63 years old. Do you all think his life is > in > > danger ? I'm thinking that hormonotherapy is probably the best > thing > > considering the situation. > > > > > > Rita xxx. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 In Quebec. What's the difference between oncologist and urologist ? Rita. > > > > Hi Rita, > > So sorry about your dad. By all means, he should see a good oncologist > who specializes in prostate cancer. Where do you live? Dr. Bob Liebowitz > in Los Angeles has had some very good success by placing his patients > on complete hormone ablation for one year, the let them go off therapy, > except for Proscar or Avodart maintenance. The PSA is closely monitored > and if it rises, then go back on treatment. This is called Intermittent > therapy. > It seems to work well for many men. > > > > I wish you all the best > > Aubrey Pilgrim, DC (Ret.) Author of > A Revolutionary Approach to Prostate Cancer-Read the original book > for FREE at: _http://www.prostatepointers.org/prostate/lay/apilgrim/_ > (http://www.prostatepointers.org/prostate/lay/apilgrim/) > Read new edition for FREE at > _http://www.cancer.prostate-help.org/capilgr.htm_ (http://www.cancer.prostate-help.org/capilgr.htm) > Dr. E. Crawford is co-author of the revision > > > > > > > In a message dated 2/21/2007 8:40:57 P.M. Eastern Standard Time, > rditanna@... writes: > > > > > My father just got his PSA result (done one month after RP) = 1.2 . > The doc is really disappointed. He says it should have been = 0 . > What does this mean ??? He's now telling my dad he has to do > radiotherapy + hormono (Casodex 50mg/day for 1 month + Zoladex 10.8 > mg/3 months for 3 years minimum). HOLY COW !!! I don't understand > WHY he suggests the radio (please read last update below). > > Rita. > > > > > > > > > <BR><BR><BR>**************************************<BR> AOL now offers free > email to everyone. Find out more about what's free from AOL at > http://www.aol.com. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Rita - No, at least based on what I know, have read etc over the last two years.ADT simply cuts off the supply of testosterone via the testicles. Testosterone in the 'vehicle'PSA uses to circulate throughout the blood system. In theory, ADT only lowers the PSA byhelping lessen the number PSA cells in the blood system. By doing so it can help shrink the tumorsin the metastasized areas. This can work for years, in some cases. EmersonFaith-Love-Hope-Winwww.flhw.org"the Big C" Re: Post RP Update #2 - BAD NEWS Can ADT cure some people ? Do some cancer cells die after ADT ? Rita. > > > > Well, we got the results post RP (prostate + lymph node analysed) > > and we're pretty disappointed but not surprised : > > > > My father's Gleason was upgraded to a 9 (instead of an 8). The > > urologist analysed a lymph node (ganglion) and he found micro- mets > > in the sample. You guys/gals were right : The cancer has escaped > the > > prostate (but it didn't show up on any tests : bone scan, taco, > > etc.) ... Too small. > > > > The urologist said it's the first time in 25 years he's seen > > this ... I find that hard to believe. He wants to consult the > other > > urologist to see what should be our next BEST step (either > external > > radiation, hormonotherapy, etc.). > > > > I really need your imput ... > > > > What do you all think ? If there are micro-mets in a lymph node, > > there's a chance that there may be some more elsewhere. The doc is > > telling us that hormonotherapy has a lot of side effects (what are > > they?) and of course I don't trust external radiation at this > point > > because I'm afraid there are mets elsewhere. What else should we > be > > looking at ? He's only 63 years old. Do you all think his life is > in > > danger ? I'm thinking that hormonotherapy is probably the best > thing > > considering the situation. > > > > > > Rita xxx. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Oncologists are physicians who study, diagnose, and treat cancerous tumors. They practice in hospitals and medical centers, university hospitals, and research organizations. To become certified as an oncologist, a candidate must first graduate from an accredited medical school before entering into training as a specialist (e.g., internist, pediatrician) and subspecialist (e.g., medical oncologist, pediatric oncologist-hematologist). There are several oncology specialties and subspecialties: Gynecological oncology: The American Board of Obstetrics and Gynecology (ABOG) examines and certifies obstetricians and gynecologists who choose to acquire additional education and training to subspecialize in the diagnosis and treatment of cancers of the female reproductive organs (e.g., cervical cancer, breast cancer). See gynecologic oncologist for more information. Medical oncology: The American Board of Internal Medicine (ABIM) examines and certifies internists who choose to acquire additional education and training to subspecialize in medical oncology, the use of medical and chemotherapeutic treatments of cancer. Medical oncology and hematology: The American Board of Internal Medicine (ABIM) examines and certifies internists who choose to acquire additional education and training in the dual subspecialty of medical oncology and hematology (the treatment of malignancies of the blood and blood-forming tissues). Pediatric oncology and hematology: The American Board of Pediatrics (ABP) examines and certifies pediatricians who choose to acquire additional education and training to subspecialize in the diagnosis and treatment of cancers in children (e.g., leukemia). Radiation oncology: The American Board of Radiology (ABR) examines and certifies radiation oncologists, who specialize in radiation treatment of cancers. Surgical oncology: The American Board of Surgery (ABS) examines and certifies surgeons who are trained in several types of surgical treatments, including biopsy, tumor staging, and tumor resection (removal). http://www.oncologychannel.com/oncologist.shtml Unfortunately we do not have, that I know of, certification for urological oncologists but they are known within the community as individuals who specialize or treat a large number of prostate cancer patients.’That means they are more likely to be aware of newer cutting edge treatments. A urologist is a physician who has specialized knowledge and skill regarding problems of the male and female urinary tract and the male reproductive organs. Because of the variety of clinical problems encountered, knowledge of internal medicine, pediatrics, gynecology, and other specialties is required of the urologist. Urology is classified as a surgical subspecialty. A urologist with advanced qualifications in surgery may be a fellow of the American College of Surgeons (FACS). Specialties Within Urology The American Urological Association has identified eight subspecialty areas: Pediatric urology Urologic oncology Renal transplantation Male infertility Urinary tract stones Female urology Neurourology Erectile dysfunction (impotence) http://www.urologychannel.com/urologist.shtml The short answer is that the urologists are normally the specialists in localized disease although they also may treat more advanced disease while oncologists emphasize more advanced disease. Ideally everyone should work with a team of physicians from the beginning, a urologist, oncologist, radiation oncologist. When you talk to someone with a different focus you will be more likely get a broader idea of how to treat the disease. Kathy Meade From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of Rita Sent: Thursday, February 22, 2007 9:11 AM To: ProstateCancerSupport Subject: Re: Post RP Update #2 - BAD NEWS In Quebec. What's the difference between oncologist and urologist ? Rita. > > > > Hi Rita, > > So sorry about your dad. By all means, he should see a good oncologist > who specializes in prostate cancer. Where do you live? Dr. Bob Liebowitz > in Los Angeles has had some very good success by placing his patients > on complete hormone ablation for one year, the let them go off therapy, > except for Proscar or Avodart maintenance. The PSA is closely monitored > and if it rises, then go back on treatment. This is called Intermittent > therapy. > It seems to work well for many men. > > > > I wish you all the best > > Aubrey Pilgrim, DC (Ret.) Author of > A Revolutionary Approach to Prostate Cancer-Read the original book > for FREE at: _http://www.prostatepointers.org/prostate/lay/apilgrim/_ > (http://www.prostatepointers.org/prostate/lay/apilgrim/) > Read new edition for FREE at > _http://www.cancer.prostate-help.org/capilgr.htm_ (http://www.cancer.prostate-help.org/capilgr.htm) > Dr. E. Crawford is co-author of the revision > > > > > > > In a message dated 2/21/2007 8:40:57 P.M. Eastern Standard Time, > rditanna@... writes: > > > > > My father just got his PSA result (done one month after RP) = 1.2 . > The doc is really disappointed. He says it should have been = 0 . > What does this mean ??? He's now telling my dad he has to do > radiotherapy + hormono (Casodex 50mg/day for 1 month + Zoladex 10.8 > mg/3 months for 3 years minimum). HOLY COW !!! I don't understand > WHY he suggests the radio (please read last update below). > > Rita. > > > > > > > > > <BR><BR><BR>**************************************<BR> AOL now offers free > email to everyone. Find out more about what's free from AOL at > http://www.aol.com. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Rita, There have been no studies that show that hormones do cure men and the medical community considers it palliative care but I had one doctor say that there are some men who live man years with hormone therapy and in fact may be taken off hormones and do not have a recurrence. It is not true with most men though unfortunately. I do not like the word “cure”. Cancer is a disease that may come back even after years of no symptoms or signs of growth. It can just quietly hide in the body so patients need to be closely monitored. Kathy From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of Emerson Sent: Thursday, February 22, 2007 9:50 AM To: ProstateCancerSupport Subject: Re: Re: Post RP Update #2 - BAD NEWS Rita - No, at least based on what I know, have read etc over the last two years. ADT simply cuts off the supply of testosterone via the testicles. Testosterone in the 'vehicle' PSA uses to circulate throughout the blood system. In theory, ADT only lowers the PSA by helping lessen the number PSA cells in the blood system. By doing so it can help shrink the tumors in the metastasized areas. This can work for years, in some cases. Emerson Faith-Love-Hope-Win www.flhw.org " the Big C " Re: Post RP Update #2 - BAD NEWS Can ADT cure some people ? Do some cancer cells die after ADT ? Rita. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Rita The oncologist: http://en.wikipedia.org/wiki/Oncology The Urologist: http://en.wikipedia.org/wiki/Urology "il faut d'abord durer." Hemingway Re: Post RP Update #2 - BAD NEWS In Quebec. What's the difference between oncologist and urologist ?Rita.>> > > Hi Rita,> > So sorry about your dad. By all means, he should see a good oncologist> who specializes in prostate cancer. Where do you live? Dr. Bob Liebowitz> in Los Angeles has had some very good success by placing his patients> on complete hormone ablation for one year, the let them go off therapy,> except for Proscar or Avodart maintenance. The PSA is closely monitored> and if it rises, then go back on treatment. This is called Intermittent > therapy.> It seems to work well for many men.> > > > I wish you all the best> > Aubrey Pilgrim, DC (Ret.) Author of> A Revolutionary Approach to Prostate Cancer-Read the original book > for FREE at: _http://www.prostatepointers.org/prostate/lay/apilgrim/_ > (http://www.prostatepointers.org/prostate/lay/apilgrim/) > Read new edition for FREE at > _http://www.cancer.prostate-help.org/capilgr.htm_ (http://www.cancer.prostate-help.org/capilgr.htm) > Dr. E. Crawford is co-author of the revision> > > > > > > > > > > > My father just got his PSA result (done one month after RP) = 1.2 . > The doc is really disappointed. He says it should have been = 0 . > What does this mean ??? He's now telling my dad he has to do > radiotherapy + hormono (Casodex 50mg/day for 1 month + Zoladex 10.8 > mg/3 months for 3 years minimum). HOLY COW !!! I don't understand > WHY he suggests the radio (please read last update below).> > Rita.> > > > > > > > > <BR><BR><BR>**************************************<BR> AOL now offers free > email to everyone. Find out more about what's free from AOL at > http://www.aol.com.> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Hi , The answer you gave is not quite right. Prostate Cancer cells must have testosterone in order to live. It is like a food for them. Incidentally, breast cancer cells also must have estrogen in order to survive. In some cases, the cancer cells may evolve to the point where they can survive without the hormones. In that case we have to resort to chemotherapy or some of the other therapies. Cancer cells also must have a good blood supply in order to grow. So they produce a substance which causes the body to grow new blood vessels just to feed them. This is called angiogenesis. There are several anti-angiogenesis drugs which are being tested. These drugs will help to counteract the cancer substance which causes the body to build new blood vessels. I wish you all the bestAubrey Pilgrim, DC (Ret.) Author ofA Revolutionary Approach to Prostate Cancer-Read the original book for FREE at: http://www.prostatepointers.org/prostate/lay/apilgrim/Read new edition for FREE at http://www.cancer.prostate-help.org/capilgr.htmDr. E. Crawford is co-author of the revision Rita - No, at least based on what I know, have read etc over the last two years.ADT simply cuts off the supply of testosterone via the testicles. Testosterone in the 'vehicle'PSA uses to circulate throughout the blood system. In theory, ADT only lowers the PSA byhelping lessen the number PSA cells in the blood system. By doing so it can help shrink the tumorsin the metastasized areas. This can work for years, in some cases. EmersonFaith-Love-Hope-Winwww.flhw.org"the Big C" Re: Post RP Update #2 - BAD NEWS Can ADT cure some people ? Do some cancer cells die after ADT ?Rita. AOL now offers free email to everyone. Find out more about what's free from AOL at AOL.com. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Rita, As Kathy says, in unusual cases, a very few men do not have a recurrence after stopping ADT (Androgen Deprivation Therapy). One such man is Doug Adam whose story is here http://www.yananow.net/Mentors/DougA.htm Although he was a young man when he was diagnosed in 1991, he had a Gleason Score of 5+5=10 – as high as you can get. He had surgery, radiotherapy and hormone therapy. In his latest update of his story he says: <snip> After stopping all treatment in 19th August 1998, my PSA is still less than 0.1 ng/ml and I am in good nick apart from increasingly creaky bones! I was diagnosed in 1991 so after 15 years, that is a great result and I pray it continues! <snip> There are no guarantees in this life – certainly not as far as prostate cancer is concerned, but stories like Doug’s show that there is often life after diagnosis. I am sure we all hope that your father’s results will be as good as Doug’s. All the best, Terry Herbert in Melbourne, Australia Diagnosed ‘96: Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. February '07 PSA 30.4 My site is at www.yananow.net As a physician, I am painfully aware that most of the decisions we make with regard to prostate cancer are made with inadequate data: Dr “Snuffy” Myers. From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of Kathy Meade Sent: Friday, 23 February 2007 2:08 AM To: ProstateCancerSupport Subject: RE: Re: Post RP Update #2 - BAD NEWS Rita, There have been no studies that show that hormones do cure men and the medical community considers it palliative care but I had one doctor say that there are some men who live man years with hormone therapy and in fact may be taken off hormones and do not have a recurrence. It is not true with most men though unfortunately. I do not like the word “cure”. Cancer is a disease that may come back even after years of no symptoms or signs of growth. It can just quietly hide in the body so patients need to be closely monitored. Kathy From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of Emerson Sent: Thursday, February 22, 2007 9:50 AM To: ProstateCancerSupport Subject: Re: Re: Post RP Update #2 - BAD NEWS Rita - No, at least based on what I know, have read etc over the last two years. ADT simply cuts off the supply of testosterone via the testicles. Testosterone in the 'vehicle' PSA uses to circulate throughout the blood system. In theory, ADT only lowers the PSA by helping lessen the number PSA cells in the blood system. By doing so it can help shrink the tumors in the metastasized areas. This can work for years, in some cases. Emerson Faith-Love-Hope-Win www.flhw.org " the Big C " ----- Original Message ---- From: Rita <rditannaglobetrotter (DOT) net> To: ProstateCancerSupport Sent: Thursday, February 22, 2007 8:08:07 AM Subject: Re: Post RP Update #2 - BAD NEWS Can ADT cure some people ? Do some cancer cells die after ADT ? Rita. Quote Link to comment Share on other sites More sharing options...
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