Guest guest Posted November 25, 2006 Report Share Posted November 25, 2006 I'm 68 years old, 4 months post-treatment for PC with modulated beam treatment. PSA 0.0634. I might add that treatment was uneventful. LUPRON caused expected effects DURING treatment, however 4 months out testicular atrophy, and recently,swelling and tenderness of my nipples lead me to believe other things may be wrong. Went to my URO, no help, " can't give hormone supplements to cancer patients " . HMMMMMMMMM, my wife is ex-cancer patient, for breast cancer, and she's on hormones. Nipple tenderness and breast swelling, shrunken testicles, extreme lethargy, plus ZERO libido, and total ED tells me I need some intervention. Is it time to see an Endocrinologist, or is this going to be my condition till I die? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 25, 2006 Report Share Posted November 25, 2006 Hi rustyduck. I would suggest that it is time to visit www.cancerimmunity.org and follow up on anything that Zheng Cui has published on his work with mice. Larry I'm 68 years old, 4 months post-treatment for PC with modulated beam treatment. PSA 0.0634. I might add that treatment was uneventful.LUPRON caused expected effects DURING treatment, however 4 months out testicular atrophy, and recently,swelling and tenderness of my nipples lead me to believe other things may be wrong.Went to my URO, no help, "can't give hormone supplements to cancer patients".HMMMMMMMMM, my wife is ex-cancer patient, for breast cancer, and she's on hormones.Nipple tenderness and breast swelling, shrunken testicles, extreme lethargy, plus ZERO libido, and total ED tells me I need some intervention.Is it time to see an Endocrinologist, or is this going to be my condition till I die? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 25, 2006 Report Share Posted November 25, 2006 Hi there, Everyone reacts differently to treatment and side effects are varied. What you describe are some pretty standard side effects from what is often called “hormone treatment” but is more correctly known as ADT (Androgen Deprivation Therapy). Apart from the breast enlargement, most of the symptoms of the side effects should fade if you stop ADT – that is why some men choose intermittent therapy, although there are some dangers and problems with that choice and it requires close monitoring. The changes to your breast are likely to be permanent – they could possily have been prevented by having a low dose of radiation before commencing your ADT. It seems from what you have said that you received a Lupron shot (which is one type of ADT) either before or after your radiation treatment. Is that so and di you only get one shot? Are you on any other medication? What did you expect your urologist to give you by the way of “hormone treatment” to alleviate your symptoms? It seems to me that your best bet would be to consult a medical oncologist rather than a uroplogist. All the best Terry Herbert in Melbourne Australia Diagnosed ‘96: Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. June '04: TURP. Nov '06 PSA 31.4 My site is at www.prostatecancerwatchfulwaiting.co.za It is a tragedy of the world that no one knows what he doesn’t know, and the less a man knows, the more sure he is that he knows everything. Joyce Carey From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of rustyduck770 Sent: Sunday, 26 November 2006 2:20 AM To: ProstateCancerSupport Subject: Permanent LUPRON Effects or what? I'm 68 years old, 4 months post-treatment for PC with modulated beam treatment. PSA 0.0634. I might add that treatment was uneventful. LUPRON caused expected effects DURING treatment, however 4 months out testicular atrophy, and recently,swelling and tenderness of my nipples lead me to believe other things may be wrong. Went to my URO, no help, " can't give hormone supplements to cancer patients " . HMMMMMMMMM, my wife is ex-cancer patient, for breast cancer, and she's on hormones. Nipple tenderness and breast swelling, shrunken testicles, extreme lethargy, plus ZERO libido, and total ED tells me I need some intervention. Is it time to see an Endocrinologist, or is this going to be my condition till I die? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 26, 2006 Report Share Posted November 26, 2006 I had the usual " pre rad -treatment " LUPRON Depot injection to induce chemical castration (shutdown Testosterone production). That was 9 months ago. Hypogonadism should NOT be significant after 9 months, neither should breast swelling/nipple tenderness. T to E blood work will reveal status, I presume. Uro hasn't done that. (He's not inspiring me) What I was wondering was has anyone experienced these latent problems after LUPRON, OR am I having endocrine system problems? > > Hi there, > > > > Everyone reacts differently to treatment and side effects are varied. What > you describe are some pretty standard side effects from what is often called > " hormone treatment " but is more correctly known as ADT (Androgen Deprivation > Therapy). Apart from the breast enlargement, most of the symptoms of the > side effects should fade if you stop ADT - that is why some men choose > intermittent therapy, although there are some dangers and problems with that > choice and it requires close monitoring. The changes to your breast are > likely to be permanent - they could possily have been prevented by having a > low dose of radiation before commencing your ADT. > > > > It seems from what you have said that you received a Lupron shot (which is > one type of ADT) either before or after your radiation treatment. Is that so > and di you only get one shot? Are you on any other medication? What did you > expect your urologist to give you by the way of " hormone treatment " to > alleviate your symptoms? > > > > It seems to me that your best bet would be to consult a medical oncologist > rather than a uroplogist. > > > > > > > > All the best > > > > Terry Herbert > > in Melbourne Australia > > Diagnosed '96: Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. June > '04: TURP. Nov '06 PSA 31.4 > > My site is at www.prostatecancerwatchfulwaiting.co.za > > It is a tragedy of the world that no one knows what he doesn't know, and the > less a man knows, the more sure he is that he knows everything. Joyce > Carey > > > > _____ > > From: ProstateCancerSupport > [mailto:ProstateCancerSupport ] On Behalf Of rustyduck770 > Sent: Sunday, 26 November 2006 2:20 AM > To: ProstateCancerSupport > Subject: Permanent LUPRON Effects or what? > > > > I'm 68 years old, 4 months post-treatment for PC with modulated beam > treatment. PSA 0.0634. I might add that treatment was uneventful. > > LUPRON caused expected effects DURING treatment, however 4 months out > testicular atrophy, and recently,swelling and tenderness of my nipples > lead me to believe other things may be wrong. > > Went to my URO, no help, " can't give hormone supplements to cancer > patients " . > > HMMMMMMMMM, my wife is ex-cancer patient, for breast cancer, and she's > on hormones. > > Nipple tenderness and breast swelling, shrunken testicles, extreme > lethargy, plus ZERO libido, and total ED tells me I need some > intervention. > Is it time to see an Endocrinologist, or is this going to be my > condition till I die? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 26, 2006 Report Share Posted November 26, 2006 It is by no means ‘usual’ to have ADT (Androgen Deprivation Therapy) prior to radiation treatment. Many radiologists do this, but by no means all because studies have demonstrated that there may be no advantage for the increased risk of side effects. I have read reports of men having a similar reaction to yours following administration of Lupron. The recovery period varied from a fairly short time to years and there were even reports of no recovery. I seem to recall that there was a law suit against the manufacturers over the issue some time back – there certainly was one by some women who had severe side effects. All the best Terry Herbert in Melbourne Australia Diagnosed ‘96: Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. June '04: TURP. Nov '06 PSA 31.4 My site is at www.prostatecancerwatchfulwaiting.co.za It is a tragedy of the world that no one knows what he doesn’t know, and the less a man knows, the more sure he is that he knows everything. Joyce Carey From: ProstateCancerSupport [mailto:ProstateCancerSupport ] On Behalf Of rustyduck770 Sent: Monday, 27 November 2006 12:56 AM To: ProstateCancerSupport Subject: Re: Permanent LUPRON Effects or what? I had the usual " pre rad -treatment " LUPRON Depot injection to induce chemical castration (shutdown Testosterone production). That was 9 months ago. Hypogonadism should NOT be significant after 9 months, neither should breast swelling/nipple tenderness. T to E blood work will reveal status, I presume. Uro hasn't done that. (He's not inspiring me) What I was wondering was has anyone experienced these latent problems after LUPRON, OR am I having endocrine system problems? > > Hi there, > > > > Everyone reacts differently to treatment and side effects are varied. What > you describe are some pretty standard side effects from what is often called > " hormone treatment " but is more correctly known as ADT (Androgen Deprivation > Therapy). Apart from the breast enlargement, most of the symptoms of the > side effects should fade if you stop ADT - that is why some men choose > intermittent therapy, although there are some dangers and problems with that > choice and it requires close monitoring. The changes to your breast are > likely to be permanent - they could possily have been prevented by having a > low dose of radiation before commencing your ADT. > > > > It seems from what you have said that you received a Lupron shot (which is > one type of ADT) either before or after your radiation treatment. Is that so > and di you only get one shot? Are you on any other medication? What did you > expect your urologist to give you by the way of " hormone treatment " to > alleviate your symptoms? > > > > It seems to me that your best bet would be to consult a medical oncologist > rather than a uroplogist. > > > > > > > > All the best > > > > Terry Herbert > > in Melbourne Australia > > Diagnosed '96: Age 54: Stage T2b: PSA 7.2: Gleason 3+3=6: No treatment. June > '04: TURP. Nov '06 PSA 31.4 > > My site is at www.prostatecancerwatchfulwaiting.co.za > > It is a tragedy of the world that no one knows what he doesn't know, and the > less a man knows, the more sure he is that he knows everything. Joyce > Carey > > > > _____ > > From: ProstateCancerSupport > [mailto:ProstateCancerSupport ] On Behalf Of rustyduck770 > Sent: Sunday, 26 November 2006 2:20 AM > To: ProstateCancerSupport > Subject: Permanent LUPRON Effects or what? > > > > I'm 68 years old, 4 months post-treatment for PC with modulated beam > treatment. PSA 0.0634. I might add that treatment was uneventful. > > LUPRON caused expected effects DURING treatment, however 4 months out > testicular atrophy, and recently,swelling and tenderness of my nipples > lead me to believe other things may be wrong. > > Went to my URO, no help, " can't give hormone supplements to cancer > patients " . > > HMMMMMMMMM, my wife is ex-cancer patient, for breast cancer, and she's > on hormones. > > Nipple tenderness and breast swelling, shrunken testicles, extreme > lethargy, plus ZERO libido, and total ED tells me I need some > intervention. > Is it time to see an Endocrinologist, or is this going to be my > condition till I die? > Quote Link to comment Share on other sites More sharing options...
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