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Hypo Unawareness

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The endo has adjusted Carey's morning insulin dose. Since returning to work he

was starting to have hypos early in the morning (2 hrs after breakfast). That is

when the rapid acting insulin in the Humalog hits it's peak. He was actually

getting down into the 30s before having a reaction and one day he was at 29! He

always keeps a snacks, a small kiddie apple juice, and glucose tablets with him

at work. Luckily, he didn't have any problem with physically being able to get

food. For his first month back at work, he has another person working with him

at all times in case something like that happens. I also call him about 2-3

times a day on his cell phone...especially in the morning when he may be

low...which I am sure he appreciates! ;-) He is testing a lot right

now...probably 8-10 times a day. I was with him one day when he tested in the

30s and you couldn't tell. He tested his sugar and was surprised how low it

was...then he tested again because he couldn't believe it. He is usually getting

the shakes and sweating in the 30s.

Re: Hypo Unawareness

In a message dated 01-01-16 22:18:42 EST, you write:

<<

We (Carey & I) have a question about hypo unawareness. What is the

definition, exactly? Does it include someone who would get down to

say 20s or 30s before they have a reaction or is it just when someone

has no indication at all that it is coming on and they just pass out?

>>

Hi, Donna..I have hypo unawareness (also have hyper unawareness)...I can go

as low as mid 40s without feeling any different than I usually do...or can go

up as high as 275 feeling the same, which is generally energetic. Sometimes

within a two-hour period. That's why I test up to ten times a day.

Considering the fact that anything under 65 is considered a hypo, that

qualifies. At low 40s I start to feel spacy and sweaty. I've never gone

below 38 (that I know of). I always carry glucose tabs with me and have them

stashed around the house in various places too. Doesn't happen very often

now, thank goodness, just now and then. Vicki

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In a message dated 01-01-16 22:18:42 EST, you write:

<<

We (Carey & I) have a question about hypo unawareness. What is the

definition, exactly? Does it include someone who would get down to

say 20s or 30s before they have a reaction or is it just when someone

has no indication at all that it is coming on and they just pass out?

>>

Hi, Donna..I have hypo unawareness (also have hyper unawareness)...I can go

as low as mid 40s without feeling any different than I usually do...or can go

up as high as 275 feeling the same, which is generally energetic. Sometimes

within a two-hour period. That's why I test up to ten times a day.

Considering the fact that anything under 65 is considered a hypo, that

qualifies. At low 40s I start to feel spacy and sweaty. I've never gone

below 38 (that I know of). I always carry glucose tabs with me and have them

stashed around the house in various places too. Doesn't happen very often

now, thank goodness, just now and then. Vicki

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In a message dated 01/17/2001 12:47:52 AM Eastern Standard Time,

whimsy2@... writes:

<< Doesn't happen very often

now, thank goodness, just now and then. Vicki >>

I do have awareness, now more than I used to, I'm lucky.

As I said before I had to increase my U due to my skin wound infections, but

Endo says she doubts beta cells return after an illness or infection so she

expects I'll need the high doses of insulin from now on, although, who knows,

could change, but I doubt it.

but anyway, I forgot to account for decrease in my IR, so of course my H

needs would decrease with U increase. Sure enough, I took my H for my food

this afternoon, and I was feeling very shaky 4 hours later, very unusual for

me, its always been 2 hours tops for a H peak.

I tested at 70, so when I start feeling a low, that means its on the way

down, so I popped 2 glucose tabs and it was up to 110 30 min later, then I

ate as usual.

My x was 20, but now its 30 for Humalog, big difference, plus now I have to

allow for 4 hours, not 2.

carol

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This will get posted twice...I should have posted right on e-

groups...my stuff is not posting AGAIN.

We (Carey & I) have a question about hypo unawareness. What is the

definition, exactly? Does it include someone who would get down to

say 20s or 30s before they have a reaction or is it just when someone

has no indication at all that it is coming on and they just pass out?

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The endo has adjusted Carey's morning insulin dose. Since returning

to work he was starting to have hypos early in the morning (2 hrs

after breakfast). That is when the rapid acting insulin in the

Humalog hits it's peak. He was actually getting down into the 30s

before having a reaction and one day he was at 29! He always keeps a

snacks, a small kiddie apple juice, and glucose tablets with him at

work. Luckily, he didn't have any problem with physically being able

to get food. For his first month back at work, he has another person

working with him at all times in case something like that happens. I

also call him about 2-3 times a day on his cell phone...especially in

the morning when he may be low...which I am sure he appreciates! ;-)

He is testing a lot right now...probably 8-10 times a day. I was with

him one day when he tested in the 30s and you couldn't tell. He

tested his sugar and was surprised how low it was...then he tested

again because he couldn't believe it. He is usually getting the

shakes and sweating in the 30s.

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Donna Gardner wrote:

<< We (Carey & I) have a question about hypo unawareness ... Does it

include someone who would get down to say 20 or 30 before they have a

reaction or is it just when someone has no indication at all that it

is coming on and they just pass out? >>

Both of those, Donna. It seems to arise from a person experiencing

too many hypos. At first, the body panics and shouts MAYDAY MAYDAY to

get your attention, but eventually, it just shrugs: " Oh, just

another one of those things. " That's a truly dangerous situation. If

we are a type 2 in poor control, we can *feel* hypo-y at or above

100, but we're not actually in trouble physically. However, as we

gain better control, we don't experience hypos until the numbers dip

lower. If we see a 65, we should immediately treat it, whether or not

we feel hypo-y. (And if it's just before bedtime, we'll want to treat

even higher numbers, like 75 or more.) Generally, the people who must

worry are those on insulin and on sulfonylureas.

Susie

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Donna Gardner wrote:

<< Carey was taking 22 units of humalog with breakfast and 18 at

dinner. Today he took 18 with breakfast (doctor's dose) and still had

a hypo (33) at about 9:00-9:30. He called the doctor and now his

breakfast dose is down to 15. We have someone from Diesentronic

coming tomorrow to show Carey the pump. Hopefully, that should

provide him with some better control... >>

Donna, I've been away and I'm confused. How many grams of carbs is

Carey eating a day? That's a LOT of Humalog! He may not need the

pump - just help with adjusting his insulins and food intake.

Susie

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Donna Gardner wrote:

<< We are not using any insulin to carb ratio. We are just going by

the diet the dietician gave us and the endo set the insulin dosage. >>

If you don't already have " Dr. Bernstein's Diabetes Solution, " I hope

you'll get it ASAP. Meanwhile, Ron Sebol's meticulous suggestions for

tight control would be a great help for you both. You really will

want to count Carey's carbs and inject accordingly at each meal (not

just twice a day). And since he is a type 1, he will need a good

background insulin such as UltraLente, injected once or twice a day.

I'll bet anything the dietitian placed Carey on a *high*-carb diet,

which makes control that much more difficult. It's what Dr. Bernstein

calls the Law of Small Numbers ... match small amounts of insulin to

small amounts of carbohydrates. That way, being the fallible humans

we all are, if you are off by 30%, the consequences won't be so

devastating.

Susie

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Donna Gardner wrote:

<< Let me clarify...this is a 75/25 Humalog mix pen. He is a type

1...his antibody test came back positive. Is this a lot of insulin? >>

Yes it's a lot of insulin. Thanks for clarifying. That 75/25 mix is

75% insulin lispro protamine suspension and 25% insulin lispro

injection (rDNA origin). Its peak is 1-1/2 to 2-1/2 hours after

injection, with a long tail. It is mostly out of the system in 14-16

hours.

This 75/25 mix is much different from regular Humalog because its

peak kicks in a bit slower, lasts a bit longer, and it has a really

long tail. Carey would not want to inject 75/25 at each meal, unless

he used very small amounts. The tails would overlap.

Susie

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Donna Gardner asked:

<< Do you think 15 (75/25) at breakfast and 15 (75/25) at dinner is

more than a type 1 would use? >>

There's often a time lag on posts, Donna, so things have a way of

cascading. I think what confused folks is we assumed Carey was using

straight Humalog and not 75/25. Straight Humalog is mostly out of the

system in 4, and certainly 5 hours, whereas 75/25 is not out of the

system entirely until 22 hours (although mostly out in 14-16 hours).

Susie

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> The 25% is the fast-acting. 75% is long-acting. I had to check out which

> was which so I could get control with it.

>

>

Wow, you're kidding! ~~ LOL, all this time I thought it was the other way

around :o)

D.

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