Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 TDR, Personal opinon: Jumping to DES (diethylstilbestrol) is like jumping to HDK (High Dose Ketoconazole) and these are later drugs when the antiandrogens " fail. " You antiandrogen is not failing, it is presumably the cause of your diarrhea. There are medications for diarrhea and since you can't get to your urologist/oncologist before Friday, possibly you could get to your family physician to determine what might work to stem the problem. Flutamide might be the culprit, but then again it may not. Something as simple as imodium may solve the problem. Here is info regarding treating diarrhea: http://www.medicinenet.com/diarrhea/page8.htm. I would not be jumping to DES at this point. (Chuck) Maack Prostate Cancer Advocate Bio: http://www.ustoowichita.org/leaders.cfm?content=bio & id=1 Email: maack1@... > > > > > > I've a metastasized PCa, and been on HT since > > Sept. > > > > > > Think Flutamide's causing diarreaha. Called my > > doctor > > > to see if I can switch to Casodex. He won't be > > back > > > in the office till Friday. The covering doctor > > > suggested I stop taking Flutamide for a couple > > of days > > > to see if it solves the problem. > > > > > > He didn't persue switching me to Casodex. > > > > > > Because my PCa's so advanced, I'm concerned that > > an > > > interruption in treatment could be dangerous. > > > > > > Am I unduly concerned? > > > > > > TDR > > > > > > > > > > > > > > __________________________________________________________ > > ______________ > > > Looking for last minute shopping deals? > > > Find them fast with Yahoo! Search. > > > > > http://tools.search.yahoo.com/newsearch/category.php? category=shopping > > > > > > > > > > > > > __________________________________________________________ > Looking for last minute shopping deals? > Find them fast with Yahoo! Search. http://tools.search.yahoo.com/newsearch/category.php?category=shopping > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 I was replying thinking that TD may want to use this in future. You are right that Lupron is the first one to try B Re: flutamide question TDR,Personal opinon: Jumping to DES (diethylstilbestrol) is like jumping to HDK (High Dose Ketoconazole) and these are later drugs when the antiandrogens "fail." You antiandrogen is not failing, it is presumably the cause of your diarrhea. There are medications for diarrhea and since you can't get to your urologist/oncologist before Friday, possibly you could get to your family physician to determine what might work to stem the problem. Flutamide might be the culprit, but then again it may not. Something as simple as imodium may solve the problem. Here is info regarding treating diarrhea: http://www.medicinenet.com/diarrhea/page8.htm. I would not be jumping to DES at this point. (Chuck) MaackProstate Cancer AdvocateBio: http://www.ustoowichita.org/leaders.cfm?content=bio & id=1Email: maack1@...> > >> > > I've a metastasized PCa, and been on HT since> > Sept.> > > > > > Think Flutamide's causing diarreaha. Called my> > doctor> > > to see if I can switch to Casodex. He won't be> > back> > > in the office till Friday. The covering doctor> > > suggested I stop taking Flutamide for a couple> > of days> > > to see if it solves the problem. > > > > > > He didn't persue switching me to Casodex. > > > > > > Because my PCa's so advanced, I'm concerned that> > an> > > interruption in treatment could be dangerous. > > > > > > Am I unduly concerned?> > > > > > TDR > > > > > > > > > > > > >> __________________________________________________________> > ______________> > > Looking for last minute shopping deals? > > > Find them fast with Yahoo! Search. > > > >> http://tools.search.yahoo.com/newsearch/category.php?category=shopping> > >> > > > > > > > > > __________________________________________________________> Looking for last minute shopping deals? > Find them fast with Yahoo! Search. http://tools.search.yahoo.com/newsearch/category.php?category=shopping> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 18, 2007 Report Share Posted December 18, 2007 My experience with Flutamide (+ Lupron)---I asked my doctor why Flutamide and not Casodex. He gave me a long disertation about how drugs like this are all alike on the tests and trials. When I pressed him for a straight answer, he finally said Price. I was prescribed the cheaper drug because a months supply of Flutimide may cost $200, compared to $600 to $700 for Casodex. Flutamide turned my urine orange after the first week of use. Flutamide has a long list of warnings including severe liver warnings. When I told him about the orange urine, he said that has never happened in his 20 years of prescribing Flutamide, but he finally complied to my request and switched me to Casodex. One pill per day. One pill of Casodex was a lot easier to take than several flutamide pills per day. When I put the information papers side by side, Flutimide to Casodex, the warning list for Casodex was much shorter compared to Flutimide. My urine stopped turning orange when I switched. Common sense conclusion--Casodex is a better drug and was less toxic in my situation. I learned that any drug that can affect the liver should be monitored with liver tests. A baseline liver test should be taken before starting Flutimide. It should be monitored every 3 to 4 weeks. Casodex, perhaps a little longer between tests. I was monitored every 6 weeks on Casodex and I was OK. My liver numbers were OK, however they went up a little over time. I learned that drugs like Flutamide or Casodex should not be used long term. I learned that a year should have been enough, and then I should have stopped it for a while. Doctors that promote intermittent therapy have a plan for this, and the information to prescribe such a plan is very costly information. There are a lot of people on this yahoo group who promote intermittent therapy, but it needs to be done according to a doctors plan. > > > > > > > > I've a metastasized PCa, and been on HT since > > > Sept. > > > > > > > > Think Flutamide's causing diarreaha. Called my > > > doctor > > > > to see if I can switch to Casodex. He won't be > > > back > > > > in the office till Friday. The covering doctor > > > > suggested I stop taking Flutamide for a couple > > > of days > > > > to see if it solves the problem. > > > > > > > > He didn't persue switching me to Casodex. > > > > > > > > Because my PCa's so advanced, I'm concerned that > > > an > > > > interruption in treatment could be dangerous. > > > > > > > > Am I unduly concerned? > > > > > > > > TDR > > > > > > > > > > > > > > > > > > > > __________________________________________________________ > > > ______________ > > > > Looking for last minute shopping deals? > > > > Find them fast with Yahoo! Search. > > > > > > > > http://tools.search.yahoo.com/newsearch/category.php? > category=shopping > > > > > > > > > > > > > > > > > > > > __________________________________________________________ > > Looking for last minute shopping deals? > > Find them fast with Yahoo! Search. > http://tools.search.yahoo.com/newsearch/category.php? category=shopping > > > Quote Link to comment Share on other sites More sharing options...
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