Guest guest Posted September 21, 2006 Report Share Posted September 21, 2006 If you are not low, I wonder why you would have the problems you are mentioning? The receptors in the urinary tract and vaginal tract are very sensitive to lack of hormones. In fact, if I get the problem you are describing, which often comes with a urinary tract infection but not always, I used a bit of estradiol gel and it works immediately. I do not use it often since I am like you, I don't want to mess with anything I may not really need. Low testosterone also causes this and when I used test. creme, the problem cleared up. BUT, I get headaches with test. replacement so I just use the estradiol gel when I get the symptoms of dryness. I may use estradiol once a week. I use as little as possible of all the hormones. How is your progesterone and testosterone levels? -- Re: pulse >>Natural estradiol gel works wonders for that as does progesterone. But the estradiol will clear that up almost immediately!<< BUT I am not low in estrogen. NORMAL levels for post meno, why screw that up? -- Artistic Grooming- Hurricane WV My Ebay Jewelry Store http://stores.ebay.com/valeriescrystalcreations http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2006 Report Share Posted September 21, 2006 <<If you are not low, I wonder why you would have the problems you are mentioning? The receptors in the urinary tract and vaginal tract are very sensitive to lack of hormones. In fact, if I get the problem you are describing, which often comes with a urinary tract infection but not always, I used a bit of estradiol gel and it works immediately. How is your progesterone and testosterone levels?>> -------Original Message------- Val wrote: <<BUT I am not low in estrogen. NORMAL levels for post meno, why screw that up?>> Val -- I completely agree with . Even if your systemic levels of estradiol really are adequate, it is VERY common for there to still be a local deficiency in the vulvar and bladder tissues. There are tons of estradiol receptors in those tissues; and if local levels are deficient and/or estrogen receptors are shut down, it can easily lead to vestibular, vaginal and bladder tissue thinning, tearing, dryness, pain, and atrophy. Topical bio-identical estradiol (usually in conjunction with topical testosterone), works extremely well to keeps these tissues plump, healthy, and moist. It also helps maintain the proper acidic vaginal pH of about 4.5, which cuts down on the increase in bladder infections that women often experience post-menopause. Some surgeons actually use estradiol in preparation for vaginal/vestibular operations since it provides such excellent tissue support, as well as being superb, after the fact, for wound healing. Of course, being unpatentable, bio-identicals are not exactly top priority for the pharmaceutical companies, although they have actually managed to produce a few bio-identical alternatives for vaginal dryness/ atrophy, such as Estrace. It will be interesting to see how the drug that you're having a part in testing pans out. Maybe i'll be proved wrong, but my feeling is that it's yet another case of creating a drug for big profit when bio-identical would do a much better job for this specific problem. (I realize, though, after looking at some of the info on the clinical trial, that there are other functions that they're investigating, not just vaginal atrophy.) There have been studies that show that there is very little systemic absorption of estradiol when it's used on/in the vulva/vestibule. Of course, used vaginally it WOULD raise systemic estradiol levels to some degree. But that's not necessarily a bad thing. Some people argue that women continue to produce estrogen after menopause and, therefore, don't need any supplementation. But the estrogen they're producing is primarily estrone, which, without been balanced by the other two main estrogens --estradiol, the " mother " estrogen and estriol -- HAS been linked with breast cancer. And i have to add that " normal " lab values for post-menopausal estradiol are pretty much along the same lines as what is usually considered " normal " thyroid levels: far from adequate. My latest lab report lists the low end of the " normal " post-menopausal estradiol range as 5 pg/ml. This is simply ludicrous. For most women of ANY age, pre- OR post-menopausal, any estradiol level under about 90 -100 will be inadequate for providing fully all of its important benefits to heart, brain, bones, skin, muscles, libido, etc. etc. So, a person can easily be told they're " normal, " and still be quite deficient. Hollis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2006 Report Share Posted September 21, 2006 For some reason, this message never appeared. . .so i'm reposting it. If everyone else who gets individual messages DID receive it, my apologies! Hollis <<If you are not low, I wonder why you would have the problems you are mentioning? The receptors in the urinary tract and vaginal tract are very sensitive to lack of hormones. In fact, if I get the problem you are describing, which often comes with a urinary tract infection but not always, I used a bit of estradiol gel and it works immediately. How is your progesterone and testosterone levels?>> -------Original Message------- Val wrote: <<BUT I am not low in estrogen. NORMAL levels for post meno, why screw that up?>> Val -- I completely agree with . Even if your systemic levels of estradiol really are adequate, it is VERY common for there to still be a local deficiency in the vulvar and bladder tissues. There are tons of estradiol receptors in those tissues; and if local levels are deficient and/or estrogen receptors are shut down, it can easily lead to vestibular, vaginal and bladder tissue thinning, tearing, dryness, pain, and atrophy. Topical bio-identical estradiol (usually in conjunction with topical testosterone), works extremely well to keeps these tissues plump, healthy, and moist. It also helps maintain the proper acidic vaginal pH of about 4.5, which cuts down on the increase in bladder infections that women often experience post-menopause. Some surgeons actually use estradiol in preparation for vaginal/vestibular operations since it provides such excellent tissue support, as well as being superb, after the fact, for wound healing. Of course, being unpatentable, bio-identicals are not exactly top priority for the pharmaceutical companies, although they have actually managed to produce a few bio-identical alternatives for vaginal dryness/ atrophy, such as Estrace. It will be interesting to see how the drug that you're having a part in testing pans out. Maybe i'll be proved wrong, but my feeling is that it's yet another case of creating a drug for big profit when bio-identical would do a much better job for this specific problem. (I realize, though, after looking at some of the info on the clinical trial, that there are other functions that they're investigating, not just vaginal atrophy.) There have been studies that show that there is very little systemic absorption of estradiol when it's used on/in the vulva/vestibule. Of course, used vaginally it WOULD raise systemic estradiol levels to some degree. But that's not necessarily a bad thing. Some people argue that women continue to produce estrogen after menopause and, therefore, don't need any supplementation. But the estrogen they're producing is primarily estrone, which, without been balanced by the other two main estrogens --estradiol, the " mother " estrogen and estriol -- HAS been linked with breast cancer. And i have to add that " normal " lab values for post-menopausal estradiol are pretty much along the same lines as what is usually considered " normal " thyroid levels: far from adequate. My latest lab report lists the low end of the " normal " post-menopausal estradiol range as 5 pg/ml. This is simply ludicrous. For most women of ANY age, pre- OR post-menopausal, any estradiol level under about 90 -100 will be inadequate for providing fully all of its important benefits to heart, brain, bones, skin, muscles, libido, etc. etc. So, a person can easily be told they're " normal, " and still be quite deficient. Hollis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2006 Report Share Posted September 21, 2006 I also experienced hot flashes when I used estrogen. So now I cut the dose way back and put it on a couple times the day I use it, or else just use a little bit. It is probably from a lot being absorbed at one time and then when it is used up, you are low. I was prescribed the Prometrium pills which is natural progesterone in pill form. It is released more steadily, supposedly. It can also be used vaginally and my doc prefers that. However, I was not impressed with the pills in relation to the expense. -- Re: pulse/Val estradiol When I use Oestrogel now I end up with immediate hot flashes the next three days and night sweas thta night. OS a non hormonal solution seems like a greta thing to me, and this opend estrogen receptors, which is how it works. So what estrogen you have works better for releiving these symptoms. I do nto want high estrogen as it binds thyroid hormone sand I certainyl don't want to mess wiht thta! LOL -- Artistic Grooming- Hurricane WV My Ebay Jewelry Store http://stores.ebay.com/valeriescrystalcreations http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 21, 2006 Report Share Posted September 21, 2006 Val: What do you mean " opened receptors " . I read that the phytoestrogens bind with the estrogen receptors more readily than the body's own estrogen. This causes the phytoestrogens to replace estrogen and actually make you lower in estrogen. I would only want that if I had an estrogen-dependent cancer. -- Re: pulse/Val estradiol When I use Oestrogel now I end up with immediate hot flashes the next three days and night sweas thta night. OS a non hormonal solution seems like a greta thing to me, and this opend estrogen receptors, which is how it works. So what estrogen you have works better for releiving these symptoms. I do nto want high estrogen as it binds thyroid hormone sand I certainyl don't want to mess wiht thta! LOL -- Artistic Grooming- Hurricane WV My Ebay Jewelry Store http://stores.ebay.com/valeriescrystalcreations http://www.stopthethyroidmadness.com/ http://health.groups.yahoo.com/group/NaturalThyroidHormonesADRENALS/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 In a message dated 9/22/2006 8:25:38 AM Eastern Daylight Time, linnmiller@... writes: > > Prometrium is a synthetic progesterone. > > > , Technically, Linn is right: Bio-identical does not always equal " natural " -- as in naturally occuring in nature. Prometrium IS synthetic, made in a lab. But, while it's not " natural, " the end result IS bio-identical to the hormone that the body naturally produces. The semantics of differentiating between the terms " synthetic, " " natural, " and " bio-identical " can get very confusing! For example, Premarin, derived from mare's urine is completely " natural, " but certainly NOT bio-identical to any hormone a female human produces. " Progesterone USP is a chemical molecule made in the laboratory to be IDENTICAL in all respects to the natural hormone made by the ovary. It begins as building blocks found in soybeans and wild yams (diogenin, diascorea, and others); it is then purified and processed through a series of chemical changes that require enymes we don't have in our bodies. It has been available in injectable form since the 1940's and is now available as a tablet (Prometrium) or vaginal gel (Crinone). Progesterone USP is also used by compounding pharmacists to make individualized prescriptions in many forms, including tablets, supppositories, and creams. Because it is identical to the natural molecule, many women find that it has fewer unplesant side effects than progestins [which are also synthetic, but not at all bio-identical] such as Provera. " Dr. L. Vliet It's My Ovaries, Stupid! p. 27 Hollis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 Nope Prometrium is not bio-identical, I looked up the chemical make- up for someone on the adeno group who was looking for info on it. Linn > Hi Linn, maybe you're thinking of Progestin? That's > synthetic. Prometrium is natural. > > > > --- Linn wrote: > > > Prometrium is a synthetic progesterone. > > > > Linn > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 I would like to see what you looked up. Would you mind posting the link? Thanks. -- Re: pulse/Val estradiol Nope Prometrium is not bio-identical, I looked up the chemical make- up for someone on the adeno group who was looking for info on it. Linn > Hi Linn, maybe you're thinking of Progestin? That's > synthetic. Prometrium is natural. > > > > --- Linn wrote: > > > Prometrium is a synthetic progesterone. > > > > Linn > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 It was the usual fine print from the drug manufacturer itself. I don't have the reference handy, but you should be able to google Prometrium and get all the fine print including the chemical make-up, side effects, etc. Linn On Sep 22, 2006, at 12:45 PM, C. Mannelli, Ed.D. wrote: > I would like to see what you looked up. Would you mind posting the > link? > > Thanks. > > -------Original Message------- > > . > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 Thanks, I will read it. I take Prometrium and have it now. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 22, 2006 Report Share Posted September 22, 2006 It says Prometrium capsules is structurally identical to the progesterone naturally produced in a woman's body. The progesterone in Prometrium capsules is synthesized from yams. This is also my understanding of bioidentical. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 23, 2006 Report Share Posted September 23, 2006 I think it's more common with PMS for it to be a progesterone allergy. Not estrone. I see an allergist for progesterone allergy and it appears to be common. More common than we know. In fact, we can be allergic to any one of our hormones. I take sublingual dilutions of weak progesterone under the tongue to " reset " my brain's reaction to P. I have major toxic reactions to P that got worse during peri. As I adjust to the dose of antigen in my sublingual I move up to the next strength. It's mixed to parts per thousand. Here is a link of the doc I see who treats me: http://www.onlineallergycenter.com/hormoneallergies/ As I develop allergy symptoms I know to drop down in sublingual dose to " correct " the symptoms. It's very cool. Homeopathic even. You can test to see exactly which hormones you are overly sensitive to. AG > Posted by: " C. Mannelli, Ed.D. " smann > guiltedgirls > > Hollis: > > My doc also told me that after menopause when estrone is mainly > produced, a > woman can have an allergic reaction to it. Have you ever heard of > this? My > doc used to be the director of an allergy clinic. I think he also > said that > during PMS, estrone is elevated causing the allergic rx commonly > thought to > be PMS. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 23, 2006 Report Share Posted September 23, 2006 In a message dated 9/23/2006 4:56:51 AM Eastern Daylight Time, smann writes: > My doc also told me that after menopause when estrone is mainly produced, a > woman can have an allergic reaction to it. Have you ever heard of this? My > doc used to be the director of an allergy clinic. I think he also said that > during PMS, estrone is elevated causing the allergic rx commonly thought to > be PMS. > > I probably don't have all of this story correct but that is the gist of it. > > > > No, i haven't heard about allergies to estrone, but it makes sense, since it's certainly possible to have allergic reactions to one's own hormones. Your doctor's comment about estrone elevation being responsible for PMS symptoms is a new one on me. In my case, i strongly feel it's the rise in P in the luteal phase (and my P is definitely elevated) that creates the bloating, fatigue, breast pain, etc. But for those who blame estrogen, then i guess it might be a possibility. I've never had my estrone or estriol tested, just estradiol. Hollis Quote Link to comment Share on other sites More sharing options...
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