Val and other experts: Your advice: Re: Dr. Starr ?

[Guest guest]

Val,

Last ???? Below was why I started Delta instead of HC. What are your

thoughts and out of curiosity what would happen if I increased my Delta instead

of switching to HC? Would I still get the thyroid hormone into the tissues or

does one work better in some people than others? Is their mechanism of action

different?

Sorry for the ?s but I have 2 100 tablet bottles of Delta I'm trying not to

waste!

Thanks,

Elle

dtgutman wrote:

To: thyroid

Date: Thu, 10 Aug 2006 22:20:31 -0000

Subject: [thyroid] Re: Dr. Starr ?

Neither of these contains all of the adrenal hormones: DHEA,

epinephrine, and norepinephrine are not included - only cortisol. But

cortisol is a VERY important hormone for our purposes. Of the other

three, it is recommended to take DHEA to balance out the cortisol -

they work in harmony, so if one is overloaded it can throw the whole

system out of whack. But ladies, remember - we need a lot less DHEA

than the men do, so be sure not to take any more than 10-25mg. The

other two adrenal hormones are actually adrenaline and are manufactured

in a different part of the adrenal gland (the inner adrenal medulla vs.

the outer adrenal cortex). They do not play a part here.

Yes, the head person at the Broda Foundation told me last month

that prednisoline was now the preferred treatment for Hashi's - just

because it provides a more even (time-released) dosage, which keeps the

antibodies low. I've also read that it doesn't cause as much water

retention as Cortef. I actually started with cortef for a month before

switching to delta (a.k.a. prednisolone). I switched mostly because I

kept forgetting the dose, but I *had* been retaining a lot of water

with the cortef. Sure enough, this improved greatly on the delta.

However, I'm in the middle of reading " Safe Uses of Cortisol " by

Jefferies (the " master " of adrenal stuff, right?)... and from what I've

read so far, he says that the tests he's seen shows that the body

doesn't react to prednisolone as well as to natural hydrocortisone

(cortef). Hmmm... something to keep in mind.

One other interesting thing I picked up from Jefferies' book: He

recommends taking the HC with MEALS to alleviate stomach discomfort (I

just read about someone here having heartburn when taking HC!) and to

space out the dose properly. The 4th pill is to be taken at BEDTIME.

He had a very good reason for the bedtime dose, but I can't remember it

at the moment. This is a bit different that the 8am-11am-2pm-5pm

regimen recommended here. Gracia, Sam - do you know the reason for the

different schedule? Is it so that the dosage more accurately reflects

our natural levels throughout the day? Just curious. I'd be inclined

to follow Jefferies, unless there's an established reason not to.

Hope this helps!

Dori

>

> In his book, Dr. Starr says that he and Dr. both recommend

> prednisolone for adrenal support. Is that an ingredient in Cortef and

> Delta? Do they include all the adrenal hormones, or just cortisol?

>

> Thanks.

>

---------------------------------

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[Guest guest]

First yo uneed the LEAST amount of steroid that works for you. Delta is

enterc coated so it is not a good drug to split the doses. The longer

lasting the med the harder it will be for your adrenals to pivck up when

it is time ot get off this stuff. Pred lasts abotu 2.5 times longer in

the body than HC does. An dlastly I have found most folks need to

recreate their natural diurnal rythym of higher cortiosl in the mornings

tapering to veyr ow at midnight. You can;t do this with Delta at all as

it takes abotu 3-6 hours to getintoyour system and then another 12 hours

to leave. If you go higher on the Delta you are risking even more

permanent suppression of the HPA axis. Especially as you may be at a

good dose now and maybe it is just not working due to not being high

when oyu need it high, and low when oyu need it lower.

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