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Vaginal and cervical pH in normal pregnancy and pregnancy complicated by

preterm labor.

Riedewald S, Kreutzmann IM, Heinze T, Saling E.

Institute of Perinatal Medicine, Free University of

Berlin, West Germany.

A prospective study was performed in order to

determine vaginal and cervical pH in pregnancy. In normal pregnancy vaginal

pH (using

a pH meter with connected glass electrode) was found

to be between 3.8 and 4.0 (1 SD +/- 0.3) at the introitus, mid-vaginal, and at

the anterior and posterior fornix. In patients with

preterm labor (n = 50) or prolonged rupture of the membranes (PROM, n = 35) pH

was increased significantly to 4.2-4.5 (1 SD +/- 0.7)

resp. to 5.2-6.1 (1 SD +/- 0.8). Cervical pH ranges between 6.5 and 7.0 in all

groups studied. Elevated pH values are due to

disturbed vaginal flora. We recommend vaginal pH measurement for an quick

detection

of infection in cases with preterm labor and for

clarifying PROM in suspicious cases.

PMID: 2384841 [PubMed - indexed for MEDLINE]

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