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WHY you need DHEA--effects of having too little.

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1) Women with low DHEA values were 40 times more likely to have

osteoporosis than were women with normal DHEA levels.

2)DHEA has demonstrated protective effects for various cancers and

is often effective for age-related issues such as sharper memory,

enhanced immune function, energy, smooth skin, tired muscles,

cardiovascular health, accelerated weight loss, and it may increase

HDL.

3)Low blood levels of the hormone DHEA have been associated with

more severe symptoms in people with SLE (LUPUS). Preliminary trials

have suggested that 50 to 200mg per day DHEA improved symptoms in

people with SLE. One double-blind trial of women with mild to

moderate SLE found that 200mg of DHEA per day improved symptoms and

allowed a greater decrease in prednisone use, but a similar trial in

women with severe SLE found only insignificant benefits

4) Although there is some conflicting evidence, many researchers

conclude that maintaining normal levels of DHEA provides some

protection against atherosclerosis.

5) DHEA levels have been found to be low in women with rheumatoid

arthritis, a condition frequently associated with osteoporosis. In a

study of 49 postmenopausal women with rheumatoid arthritis, DHEA

levels (measured as DHEA-S ) were significantly lower than in

healthy controls.

6) Stress accelerates the loss of DHEA.

7) Insulin levels may play a significant role in determining how

much DHEA is metabolized. Studies have discovered that low levels of

DHEA may be related to an excess of insulin. What this suggests is

that anyone suffering from hypoglycemia or excess insulin may be

prone to converting nutrients to fat due to depressed DHEA levels.

If you want to read more, check out this link:

http://www.diagnose-me.com/cond/C11446.html

Janie

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In a message dated 7/21/03 12:03:13 AM Eastern Daylight Time, usns@...

writes:

> 1) Women with low DHEA values were 40 times more likely to have

> osteoporosis than were women with normal DHEA levels.

>

> 2)DHEA has demonstrated protective effects for various cancers and

> is often effective for age-related issues such as sharper memory,

> enhanced immune function, energy, smooth skin, tired muscles,

> cardiovascular health, accelerated weight loss, and it may increase

> HDL.

>

> 3)Low blood levels of the hormone DHEA have been associated with

> more severe symptoms in people with SLE (LUPUS). Preliminary trials

> have suggested that 50 to 200mg per day DHEA improved symptoms in

> people with SLE. One double-blind trial of women with mild to

> moderate SLE found that 200mg of DHEA per day improved symptoms and

> allowed a greater decrease in prednisone use, but a similar trial in

> women with severe SLE found only insignificant benefits

>

> 4) Although there is some conflicting evidence, many researchers

> conclude that maintaining normal levels of DHEA provides some

> protection against atherosclerosis.

>

> 5) DHEA levels have been found to be low in women with rheumatoid

> arthritis, a condition frequently associated with osteoporosis. In a

> study of 49 postmenopausal women with rheumatoid arthritis, DHEA

> levels (measured as DHEA-S ) were significantly lower than in

> healthy controls.

>

> 6) Stress accelerates the loss of DHEA.

>

> 7) Insulin levels may play a significant role in determining how

> much DHEA is metabolized. Studies have discovered that low levels of

> DHEA may be related to an excess of insulin. What this suggests is

> that anyone suffering from hypoglycemia or excess insulin may be

> prone to converting nutrients to fat due to depressed DHEA levels.

>

> If you want to read more, check out this link:

>

> http://www.diagnose-me.com/cond/C11446.html

>

> Janie

>

>

Janie-

Is DHEA available OTC or is it prescription only?

Is this going to be another 7 year struggle to find a doctor and not a

poophead?

Thanks,

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> Janie-

> Is DHEA available OTC or is it prescription only?

Both. You can get DHEA over the counter. Or, you can get a

prescription to have it compounded in a gel. I take mine in a gel

along with the testosterone I take in the gel. BUT, it IS over-the-

counter and appears to work fine!!

Janie

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In a message dated 7/21/03 6:06:09 AM US Eastern Standard Time,

susbarb1@... writes:

> 6) Stress accelerates the loss of DHEA.

>

I can sure attest to this one!

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OK...some devil's advocate comments on these points just to make you

think....

> 1) Women with low DHEA values were 40 times more likely to have

> osteoporosis than were women with normal DHEA levels.

OK...but at what age? They do not list the control here. There may be a

link, but what is the mechanism here?

>

> 2)DHEA has demonstrated protective effects for various cancers and

> is often effective for age-related issues such as sharper memory,

> enhanced immune function, energy, smooth skin, tired muscles,

> cardiovascular health, accelerated weight loss, and it may increase

> HDL.

I agree with this, especially for men.

>

> 3)Low blood levels of the hormone DHEA have been associated with

> more severe symptoms in people with SLE (LUPUS). Preliminary trials

> have suggested that 50 to 200mg per day DHEA improved symptoms in

> people with SLE. One double-blind trial of women with mild to

> moderate SLE found that 200mg of DHEA per day improved symptoms and

> allowed a greater decrease in prednisone use, but a similar trial in

> women with severe SLE found only insignificant benefits

> 5) DHEA levels have been found to be low in women with rheumatoid

> arthritis, a condition frequently associated with osteoporosis. In a

> study of 49 postmenopausal women with rheumatoid arthritis, DHEA

> levels (measured as DHEA-S ) were significantly lower than in

> healthy controls.

>

OK...on matters of SLE and rhuem....there is a perfectly good explanation

for this. Both are inflammatory autoimmune disieases. (rhuem is associated

with osteo because it has its own mechanism that causes bone loss) When

inflammation takes place, the body releases more cortisol to combat the

inflammation. In the first decade or two of this chronic disease, cortisol

is going to be released in abundance, as it will in any inflammatory

condition. As a result, DHEA will be low. I would bet a dollar (if I had

one) that their cortisol levels are high. Cortisol and prednisone " eat "

DHEA, making DHEA go low BECAUSE of an inflammartory condition. Autoimmune

dieases are not caused by low DHEA. Later, in the course of the disease,

cortisol will be low and DHEA will normalize, depending on how much

prednisone is used over the course of time. The reason for the conflicting

results when using DHEA in these conditions is because SLE and Rhumey are

more prominent in women. Post meno women are for whatever reason more likely

to convert DHEA to testosterone than female hormones. If the person's

testosterone levels are not bad, they will see an improvement in their

strength and muscle. Therefore, they will feel better even though it doesn't

impact the disease progression itself. It will temporarily life the weakness

and fatigue. Others, its not going to do a lot for, espcially if they have

enough testosterone to be normal in that area. Lots of claims can be made

about DHEA improving the condiion of autoimmune. However, strengthenning the

immune system with DHEA is not a long term help for these diseases. It will

be worth it if it gives a little kick and lifts the person up for a while,

because any " good days " are worth it. But eventually cortisol will drop like

a rock and DHEA will be more plentiful on its own, again, depending on how

much steroids are taken orally.

>

> 4) Although there is some conflicting evidence, many researchers

> conclude that maintaining normal levels of DHEA provides some

> protection against atherosclerosis.

In men, yes. It has not been shown to protect women from heart/artery

disease.

>

> 6) Stress accelerates the loss of DHEA.

Again, cotisol eats it. However, replacing DHEA due to high cortisol from

stress is probably a good idea.

>

> 7) Insulin levels may play a significant role in determining how

> much DHEA is metabolized. Studies have discovered that low levels of

> DHEA may be related to an excess of insulin. What this suggests is

> that anyone suffering from hypoglycemia or excess insulin may be

> prone to converting nutrients to fat due to depressed DHEA levels.

>

This I know nothing about.

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Autoimmune diseases are adrenal in origin, no matter how it came to be that

way. Once you correct the insufficiency you can get your health back.

It's just like when you take thyroid meds, many " diseases " are cured.

Gracia

Autoimmune

> dieases are not caused by low DHEA. Later, in the course of the disease,

> cortisol will be low and DHEA will normalize, depending on how much

> prednisone is used over the course of time.

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Gracia, only some are adrenal in nature, there are a lot of autoimmune diseases,

that cover the gamut in the body-----------Rheumatoid Arthritis, ITP,Sjogrens,

Wegeners, SLE, Hashimotos, Pernicious Anemia just to name a very few

Blanket statements are rarely based in real life

Feisty

Re: WHY you need DHEA--effects of having too

little.

Autoimmune diseases are adrenal in origin, no matter how it came to be that

way. Once you correct the insufficiency you can get your health back.

It's just like when you take thyroid meds, many " diseases " are cured.

Gracia

Autoimmune

> dieases are not caused by low DHEA. Later, in the course of the disease,

> cortisol will be low and DHEA will normalize, depending on how much

> prednisone is used over the course of time.

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Oh silly me! I was under the impression that cortisol and DHEA helped all

these conditions.

Gracia

> Gracia, only some are adrenal in nature, there are a lot of autoimmune

diseases, that cover the gamut in the body-----------Rheumatoid Arthritis,

ITP,Sjogrens, Wegeners, SLE, Hashimotos, Pernicious Anemia just to name a

very few

> Blanket statements are rarely based in real life

> Feisty

> Re: WHY you need DHEA--effects of

having too little.

>

>

>

> Autoimmune diseases are adrenal in origin, no matter how it came to be

that

> way. Once you correct the insufficiency you can get your health back.

> It's just like when you take thyroid meds, many " diseases " are cured.

> Gracia

>

>

> Autoimmune

> > dieases are not caused by low DHEA. Later, in the course of the

disease,

> > cortisol will be low and DHEA will normalize, depending on how much

> > prednisone is used over the course of time.

>

>

>

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