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You will also need to dump the ultram.. it can cause gastric bleeds.. My GI

doc told me this when I was on ultram, and had just undergone a revision

surgery for staple line disruption and was being treated for maginal ulcers..

I am not , but I , too, have fibromyalgia. I dont know about the

magnesium or effexor.. I was taking prozac, but it can cause liver damage,

and I have problems with my liver pre surgery.. so I take no medications for

the fibro except trazadone at bedtime to help me sleep..

Best of luck to you..

Hugs,

open RNY 12/12/00

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revision 02/07/02

sw392

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We are allowed to take tylenol arthritis.. and my pcp gave me lortab, and

vicodin for the fibro pain.. so dont suffer.. talk to your surgeon and pcp

and have something prescribed for the pain..

Hugs,

open RNY 12/12/00

revision 04/18/01

revision 02/07/02

sw392

cw 217

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Hi Sheri - I am on Effexor, too, for my fibro. Also, Salsalate and Trazadone.

Why do you think you'll need to switch to the non-time-released Effexor?

Because of the malabsorption problems after surgery? I've taken Ultram once

before, too, and it helped with my pain. But lately, the docs seem willing to

give me Vicodin. I just use it long enough for the pain to subside, then save

any leftovers for my next flair. Anyway, please share what info. you get from

your PCP and pharmacist, as I will share these with mine. Thanks.

Jeanne in WI

Re: Medication Questions -

> I have progressing osteoarthritis. I tried Celebrex (supposed to

be safe, too) and just a coupla weeks cost me MONTHS of recovery.

I use plaquenil (rx) to keep the joints mobile. I use heat for the

pain. Tylenol can damage the liver and ours aren't all that great

anyway, so I save it for special occasions. Every now & then use

valium as a special treat to get the muscles to settle down & let

everything be. I joke about tit for my brain, but I use it for a

muscle relaxant.<<<

Good Morning ,

I have a few medication questions for you. I have Fibromyalgia that

is currently being controlled fairly well with Ultram (50mg morning

and night), Mobic (15mg night), Effexor XR (75mg morning-also taken

for depression) and Magnesium (64mg morning and night). I also take

Topamax (25mg morning and night to control migraine headaches, but it

is originally an antiseizure medication).

I know I will have to dump the Mobic - I am told not to use it with

an aspirin product because of intensifying the effect, so it is a no-

no. The Effexor and Magnesium are both time release right now but

both are available in regular compounds. No mention of gastro

problems for the Effexor. The Topamax slightly increases the

possibility of kidney stones if you don't drink enough water, but no

mention of gastro problems.

The Ultram is not in the NSAIDS category - actually I was told it is

a new category of medication. This is what the insert said:

ULTRAM is a centrally acting synthetic analgesic, not a non-steroidal

anti-inflammatory drug (NSAID). ULTRAM has no anti-inflammatory

activity and no potential for prostaglandin-mediated side effects.

Unlike NSAIDs, ULTRAM does not have the potential to compromise the

efficacy of certain antihypertensive agents (diuretics, beta

blockers, and ACE-inhibitors). ULTRAM is a prescription-only pain

medicine intended for people who have moderate to moderately severe

chronic pain. ULTRAM helps your body's system relieve pain in two

important ways. Laboratory studies suggest that first, ULTRAM acts

directly on parts of the brain and spinal cord to reduce the amount

of pain. Second, it reduces the size of the pain signal passed from

one nerve to another. ULTRAM works differently from an NSAID (which

stands for nonsteroidal anti-inflammatory drug and is pronounced " EN-

sayd " ), such as ibuprofen. ULTRAM is also different from other pain

medications, such as codeine or morphine. While the mode of action of

ULTRAM is not completely understood, laboratory studies suggest that

at least two complementary mechanisms appear applicable: binding of

parent and M1 metabolite to opioid receptors and weak inhibition of

the re-uptake of norephinephrine and serotonin. ULTRAM may be a good

choice for people who need effective relief of chronic pain. This

patient group may include: People at risk of stomach ulcers. ULTRAM

has not been associated with ulcers or stomach bleeding in medical

studies. People taking certain medicines to control their high blood

pressure. ULTRAM does not interfere with the ways in which various

blood pressure medicines work. People at risk of kidney problems.

ULTRAM does not affect the hormone-like system that helps keep the

kidneys working normally; this is a special consideration in older

people.

So my questions are:

Do you think the Effexor and Magnesium are okay if I get the non-time

release formula?

What about the Topamax?

And the Ultram, what is your opinion. It works very well for the

pain, but if it will cause me great problems after surgery I need to

know.

I understand that you are not a doctor or a pharmacist and your

responses represent only your opinion in these matters, yada, yada,

yada.

My PCP is great and is willing to work with me on these issues. In

fact, when I was last in there we agreed to both research the

medication issue together and discuss it again before I go into

surgery. She will be doing my primary follow-up after the initial

healing process, so I feel good about her willingness to work with me

on this. My pharmacist also told me to come in about a month before

the surgery and he would sit down with me to review medications and

discuss my situation. Is that great or what??

But I like to have as much information as possible before I go and

talk to these people. So, thanks so much, , for your

willingness to help us with these matters.

Sheri

In Sunny Florida

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I hope you can too sweetie I had the same problems I am so glad I decided to see

a neurologist !

Re: Medication Questions -

> Sheri if these don't work I am on Neurontin(seizure drug ) ,and

zanaflex (muscle relaxer) and DR said they are fine . so far I have

had no problems . I use Doxipin too but I am almost sure the effexor

will be fine <<<

Thanks, . I have gone through so many medications to find

something that will work with the fibro, that I am hoping that I can

keep most of them. As I said, I know the Mobic has to go but it is

probably the least effective. The combo of the Effexor and the Ultram

has really helped me.

Thanks again,

Sheri

In Sunny Florida

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There is a brand new med out - by the makers of Celexa - called Bextra - as in -

its been out like 3 weeks - our family doc gave it to DH for his arthritis -

once a day -has been on it a week today - will see how it goes - and let ya know

- hugs deb in NE

Re: Medication Questions -

> I have progressing osteoarthritis. I tried Celebrex (supposed to

be safe, too) and just a coupla weeks cost me MONTHS of recovery.

I use plaquenil (rx) to keep the joints mobile. I use heat for the

pain. Tylenol can damage the liver and ours aren't all that great

anyway, so I save it for special occasions. Every now & then use

valium as a special treat to get the muscles to settle down & let

everything be. I joke about tit for my brain, but I use it for a

muscle relaxant.<<<

Good Morning ,

I have a few medication questions for you. I have Fibromyalgia that

is currently being controlled fairly well with Ultram (50mg morning

and night), Mobic (15mg night), Effexor XR (75mg morning-also taken

for depression) and Magnesium (64mg morning and night). I also take

Topamax (25mg morning and night to control migraine headaches, but it

is originally an antiseizure medication).

I know I will have to dump the Mobic - I am told not to use it with

an aspirin product because of intensifying the effect, so it is a no-

no. The Effexor and Magnesium are both time release right now but

both are available in regular compounds. No mention of gastro

problems for the Effexor. The Topamax slightly increases the

possibility of kidney stones if you don't drink enough water, but no

mention of gastro problems.

The Ultram is not in the NSAIDS category - actually I was told it is

a new category of medication. This is what the insert said:

ULTRAM is a centrally acting synthetic analgesic, not a non-steroidal

anti-inflammatory drug (NSAID). ULTRAM has no anti-inflammatory

activity and no potential for prostaglandin-mediated side effects.

Unlike NSAIDs, ULTRAM does not have the potential to compromise the

efficacy of certain antihypertensive agents (diuretics, beta

blockers, and ACE-inhibitors). ULTRAM is a prescription-only pain

medicine intended for people who have moderate to moderately severe

chronic pain. ULTRAM helps your body's system relieve pain in two

important ways. Laboratory studies suggest that first, ULTRAM acts

directly on parts of the brain and spinal cord to reduce the amount

of pain. Second, it reduces the size of the pain signal passed from

one nerve to another. ULTRAM works differently from an NSAID (which

stands for nonsteroidal anti-inflammatory drug and is pronounced " EN-

sayd " ), such as ibuprofen. ULTRAM is also different from other pain

medications, such as codeine or morphine. While the mode of action of

ULTRAM is not completely understood, laboratory studies suggest that

at least two complementary mechanisms appear applicable: binding of

parent and M1 metabolite to opioid receptors and weak inhibition of

the re-uptake of norephinephrine and serotonin. ULTRAM may be a good

choice for people who need effective relief of chronic pain. This

patient group may include: People at risk of stomach ulcers. ULTRAM

has not been associated with ulcers or stomach bleeding in medical

studies. People taking certain medicines to control their high blood

pressure. ULTRAM does not interfere with the ways in which various

blood pressure medicines work. People at risk of kidney problems.

ULTRAM does not affect the hormone-like system that helps keep the

kidneys working normally; this is a special consideration in older

people.

So my questions are:

Do you think the Effexor and Magnesium are okay if I get the non-time

release formula?

What about the Topamax?

And the Ultram, what is your opinion. It works very well for the

pain, but if it will cause me great problems after surgery I need to

know.

I understand that you are not a doctor or a pharmacist and your

responses represent only your opinion in these matters, yada, yada,

yada.

My PCP is great and is willing to work with me on these issues. In

fact, when I was last in there we agreed to both research the

medication issue together and discuss it again before I go into

surgery. She will be doing my primary follow-up after the initial

healing process, so I feel good about her willingness to work with me

on this. My pharmacist also told me to come in about a month before

the surgery and he would sit down with me to review medications and

discuss my situation. Is that great or what??

But I like to have as much information as possible before I go and

talk to these people. So, thanks so much, , for your

willingness to help us with these matters.

Sheri

In Sunny Florida

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Same family as Celebrex (for arthritis) or Celexa (anti-depressant)?

Thanks,

http://www.vitalady.com

For info on PayPal, click this link:

https://secure.paypal.com/affil/pal=vitalady%40bigfoot.com

Re: Medication Questions -

> I have progressing osteoarthritis. I tried Celebrex (supposed to

be safe, too) and just a coupla weeks cost me MONTHS of recovery.

I use plaquenil (rx) to keep the joints mobile. I use heat for the

pain. Tylenol can damage the liver and ours aren't all that great

anyway, so I save it for special occasions. Every now & then use

valium as a special treat to get the muscles to settle down & let

everything be. I joke about tit for my brain, but I use it for a

muscle relaxant.<<<

Good Morning ,

I have a few medication questions for you. I have Fibromyalgia that

is currently being controlled fairly well with Ultram (50mg morning

and night), Mobic (15mg night), Effexor XR (75mg morning-also taken

for depression) and Magnesium (64mg morning and night). I also take

Topamax (25mg morning and night to control migraine headaches, but it

is originally an antiseizure medication).

I know I will have to dump the Mobic - I am told not to use it with

an aspirin product because of intensifying the effect, so it is a no-

no. The Effexor and Magnesium are both time release right now but

both are available in regular compounds. No mention of gastro

problems for the Effexor. The Topamax slightly increases the

possibility of kidney stones if you don't drink enough water, but no

mention of gastro problems.

The Ultram is not in the NSAIDS category - actually I was told it is

a new category of medication. This is what the insert said:

ULTRAM is a centrally acting synthetic analgesic, not a non-steroidal

anti-inflammatory drug (NSAID). ULTRAM has no anti-inflammatory

activity and no potential for prostaglandin-mediated side effects.

Unlike NSAIDs, ULTRAM does not have the potential to compromise the

efficacy of certain antihypertensive agents (diuretics, beta

blockers, and ACE-inhibitors). ULTRAM is a prescription-only pain

medicine intended for people who have moderate to moderately severe

chronic pain. ULTRAM helps your body's system relieve pain in two

important ways. Laboratory studies suggest that first, ULTRAM acts

directly on parts of the brain and spinal cord to reduce the amount

of pain. Second, it reduces the size of the pain signal passed from

one nerve to another. ULTRAM works differently from an NSAID (which

stands for nonsteroidal anti-inflammatory drug and is pronounced " EN-

sayd " ), such as ibuprofen. ULTRAM is also different from other pain

medications, such as codeine or morphine. While the mode of action of

ULTRAM is not completely understood, laboratory studies suggest that

at least two complementary mechanisms appear applicable: binding of

parent and M1 metabolite to opioid receptors and weak inhibition of

the re-uptake of norephinephrine and serotonin. ULTRAM may be a good

choice for people who need effective relief of chronic pain. This

patient group may include: People at risk of stomach ulcers. ULTRAM

has not been associated with ulcers or stomach bleeding in medical

studies. People taking certain medicines to control their high blood

pressure. ULTRAM does not interfere with the ways in which various

blood pressure medicines work. People at risk of kidney problems.

ULTRAM does not affect the hormone-like system that helps keep the

kidneys working normally; this is a special consideration in older

people.

So my questions are:

Do you think the Effexor and Magnesium are okay if I get the non-time

release formula?

What about the Topamax?

And the Ultram, what is your opinion. It works very well for the

pain, but if it will cause me great problems after surgery I need to

know.

I understand that you are not a doctor or a pharmacist and your

responses represent only your opinion in these matters, yada, yada,

yada.

My PCP is great and is willing to work with me on these issues. In

fact, when I was last in there we agreed to both research the

medication issue together and discuss it again before I go into

surgery. She will be doing my primary follow-up after the initial

healing process, so I feel good about her willingness to work with me

on this. My pharmacist also told me to come in about a month before

the surgery and he would sit down with me to review medications and

discuss my situation. Is that great or what??

But I like to have as much information as possible before I go and

talk to these people. So, thanks so much, , for your

willingness to help us with these matters.

Sheri

In Sunny Florida

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Duh - its the same family as Celebrex - sorry all - can't spell - duh - senior

moment here - deb in NE

Re: Medication Questions -

> I have progressing osteoarthritis. I tried Celebrex (supposed to

be safe, too) and just a coupla weeks cost me MONTHS of recovery.

I use plaquenil (rx) to keep the joints mobile. I use heat for the

pain. Tylenol can damage the liver and ours aren't all that great

anyway, so I save it for special occasions. Every now & then use

valium as a special treat to get the muscles to settle down & let

everything be. I joke about tit for my brain, but I use it for a

muscle relaxant.<<<

Good Morning ,

I have a few medication questions for you. I have Fibromyalgia that

is currently being controlled fairly well with Ultram (50mg morning

and night), Mobic (15mg night), Effexor XR (75mg morning-also taken

for depression) and Magnesium (64mg morning and night). I also take

Topamax (25mg morning and night to control migraine headaches, but it

is originally an antiseizure medication).

I know I will have to dump the Mobic - I am told not to use it with

an aspirin product because of intensifying the effect, so it is a no-

no. The Effexor and Magnesium are both time release right now but

both are available in regular compounds. No mention of gastro

problems for the Effexor. The Topamax slightly increases the

possibility of kidney stones if you don't drink enough water, but no

mention of gastro problems.

The Ultram is not in the NSAIDS category - actually I was told it is

a new category of medication. This is what the insert said:

ULTRAM is a centrally acting synthetic analgesic, not a non-steroidal

anti-inflammatory drug (NSAID). ULTRAM has no anti-inflammatory

activity and no potential for prostaglandin-mediated side effects.

Unlike NSAIDs, ULTRAM does not have the potential to compromise the

efficacy of certain antihypertensive agents (diuretics, beta

blockers, and ACE-inhibitors). ULTRAM is a prescription-only pain

medicine intended for people who have moderate to moderately severe

chronic pain. ULTRAM helps your body's system relieve pain in two

important ways. Laboratory studies suggest that first, ULTRAM acts

directly on parts of the brain and spinal cord to reduce the amount

of pain. Second, it reduces the size of the pain signal passed from

one nerve to another. ULTRAM works differently from an NSAID (which

stands for nonsteroidal anti-inflammatory drug and is pronounced " EN-

sayd " ), such as ibuprofen. ULTRAM is also different from other pain

medications, such as codeine or morphine. While the mode of action of

ULTRAM is not completely understood, laboratory studies suggest that

at least two complementary mechanisms appear applicable: binding of

parent and M1 metabolite to opioid receptors and weak inhibition of

the re-uptake of norephinephrine and serotonin. ULTRAM may be a good

choice for people who need effective relief of chronic pain. This

patient group may include: People at risk of stomach ulcers. ULTRAM

has not been associated with ulcers or stomach bleeding in medical

studies. People taking certain medicines to control their high blood

pressure. ULTRAM does not interfere with the ways in which various

blood pressure medicines work. People at risk of kidney problems.

ULTRAM does not affect the hormone-like system that helps keep the

kidneys working normally; this is a special consideration in older

people.

So my questions are:

Do you think the Effexor and Magnesium are okay if I get the non-time

release formula?

What about the Topamax?

And the Ultram, what is your opinion. It works very well for the

pain, but if it will cause me great problems after surgery I need to

know.

I understand that you are not a doctor or a pharmacist and your

responses represent only your opinion in these matters, yada, yada,

yada.

My PCP is great and is willing to work with me on these issues. In

fact, when I was last in there we agreed to both research the

medication issue together and discuss it again before I go into

surgery. She will be doing my primary follow-up after the initial

healing process, so I feel good about her willingness to work with me

on this. My pharmacist also told me to come in about a month before

the surgery and he would sit down with me to review medications and

discuss my situation. Is that great or what??

But I like to have as much information as possible before I go and

talk to these people. So, thanks so much, , for your

willingness to help us with these matters.

Sheri

In Sunny Florida

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, and Sheri,

My GI doctor , internist, and my infectious disease doctor all said no to

Ultram.. Apparently, they did read a study in one of their medical journals

which relates gastric bleeds with the use of ultram in the higher risk

patient.. I suppose they were concerned about my taking ultram for the fibro

pain as I had already had ulcers at that point .Sheri, I sure hope that you

can continue to take this medication if it helps and not suffer any

consequences due to taking it regularly..

Hugs,

open RNY 12/12/00

revision 04/18/01

revision 02/07/02

sw392

cw 217

-175

5'6

l

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The Ultram is not in the NSAIDS category - actually I was told it is

a new category of medication. This is what the insert said:

ULTRAM is a centrally acting synthetic analgesic, not a non-steroidal

anti-inflammatory drug (NSAID). ULTRAM has no anti-inflammatory

activity and no potential for prostaglandin-mediated side effects.

Unlike NSAIDs, ULTRAM does not have the potential to compromise the

efficacy of certain antihypertensive agents (diuretics, beta

blockers, and ACE-inhibitors). ULTRAM is a prescription-only pain

medicine intended for people who have moderate to moderately severe

chronic pain. ULTRAM helps your body's system relieve pain in two

important ways. Laboratory studies suggest that first, ULTRAM acts

directly on parts of the brain and spinal cord to reduce the amount

of pain. Second, it reduces the size of the pain signal passed from

one nerve to another. ULTRAM works differently from an NSAID (which

stands for nonsteroidal anti-inflammatory drug and is pronounced " EN-

sayd " ), such as ibuprofen. ULTRAM is also different from other pain

medications, such as codeine or morphine. While the mode of action of

ULTRAM is not completely understood, laboratory studies suggest that

at least two complementary mechanisms appear applicable: binding of

parent and M1 metabolite to opioid receptors and weak inhibition of

the re-uptake of norephinephrine and serotonin. ULTRAM may be a good

choice for people who need effective relief of chronic pain. This

patient group may include: People at risk of stomach ulcers. ULTRAM

has not been associated with ulcers or stomach bleeding in medical

studies. People taking certain medicines to control their high blood

pressure. ULTRAM does not interfere with the ways in which various

blood pressure medicines work. People at risk of kidney problems.

ULTRAM does not affect the hormone-like system that helps keep the

kidneys working normally; this is a special consideration in older

people.

*************

I might try this one a few times myself. I would not take it daily.

So my questions are:

Do you think the Effexor and Magnesium are okay if I get the non-time

release formula?

************* you can try it. Wellbutrin is known NOT to cause wt gain, and

comes in non-SR version. You mean mag, as in the mineral mag? Rx strength? You

might not need it post-op, so hopefully someone wil test blood fairly fequently

on this one

What about the Topamax?

************* I've not heard/ seen anything on this one. I mean I know you

have the medical info right there, but I have no anecdotal evidence to add on

this one

And the Ultram, what is your opinion. It works very well for the

pain, but if it will cause me great problems after surgery I need to

know.

*********** I'd be nervous. Maybe do the poop-on-a-card test every few months to

make sure there is NO bleeding at all?

I understand that you are not a doctor or a pharmacist and your

responses represent only your opinion in these matters, yada, yada,

yada.

*********** yes, repeat that again

My PCP is great and is willing to work with me on these issues. In

fact, when I was last in there we agreed to both research the

medication issue together and discuss it again before I go into

surgery. She will be doing my primary follow-up after the initial

healing process, so I feel good about her willingness to work with me

on this. My pharmacist also told me to come in about a month before

the surgery and he would sit down with me to review medications and

discuss my situation. Is that great or what??

************** yes!! And too, I think that blood work to test efficacy and " the

card " will test if there is any damage being done while it is still miniscule.

But I like to have as much information as possible before I go and

talk to these people. So, thanks so much, , for your

willingness to help us with these matters.

Sheri

In Sunny Florida

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