Re: Re: research-Sharon

[Guest guest]

Margot, you and your are on my prayer list. Just a note about the fever. A child is small enought to pick up and put in the tub but when my first husband was running a very high fever and was out of his head I could not manage to get him to the tub. I kept cool wet rags on his head and put a hot water bottle or heating pad to his feet. This broke his fever within a couple of hours. HAPPINESS and BUTTERFLIES Lynnbean999_99 wrote: I haven't been doing well. I ended up in the hospital the week before Christmas with diverticulitis....colon

infection. I discovered nuts and Rebif don't mix. I am slowly on the mend. On the plus side, I have lost so much weight I now match the weight on my driver's license. I now have a colonsocopy scheduled for Janaury 10th. Happy New Year! I am so not looking forward to that!Kids are doing OK. My 9 year old has some sort of bug at the moment. She spiked a temp 105.5 last night. That scared me. I put her in a tub and then rubbed her down with alcohol. She is a bit better this morning.Never a dull moment at my house. Margot> >> > > > > > Ottawa team unravelling brain damage in multiple > sclerosis> > > > Last Updated Wed, 21 Dec 2005

13:47:38 EST > > CBC News> > > > The puzzle of how nerve coatings are damaged in the > brains of people with multiple sclerosis may have been solved by a > Canadian-led research team. > > > > Nerve fibres that send electrical signals in the brain > are coated in a fatty sheath called myelin. The myelin acts as an > insulator, like a plastic coating covering a copper wire. > > > > Neurologist Dr. Stys of the Ottawa Health > Research Institute and his colleagues proposed a reason why myelin > becomes damaged and invented a way to test the idea in the lab. > > >

> The researchers showed myelin contains specialized > receptors for glutamate, a neurotransmitter that transmits signals > to brain cells. > > > > They also found chemicals that block the receptor can > reduce myelin damage. > > > > "Such a mechanism may represent a potentially > important therapeutic target in disorders in which [myelin damage] > is a prominent feature," the researchers write in Thursday's online > issue of the journal Nature. > > > > The laboratory findings need to be confirmed and > tested in animals before a potential drug could be tried in humans. >

> > > To make the discovery, Stys's team invented a state-of-> the-art laser scanning microscope technique. It allowed the first > measurements of changes in calcium levels in the tiny spaces within > myelin in a rat model. > > > > Stys suspects glutamate from inflammatory cells may > directly injure myelin in immune disorders such as MS. > > > > The findings help fill in the details of what > molecules are involved and how they interact in MS, agreed Dr. > Waxman, neurology chair at Yale University School of > Medicine. He was not involved in the research. > > > >

The research was funded by the the National Institute > of Neurological Disorders and Stroke, the Canadian Institutes of > Health Research, the Heart and Stroke Foundation of Ontario, the > Canadian Institute for Photonic Innovations and private donors.> >> > > > > > >