Guest guest Posted December 23, 2005 Report Share Posted December 23, 2005 Thanks so much, Bill, that sending that information. Tysabri is the drug my neuro said he really wanted me to "seriously consider". What about you? Are you also thinking about it? SharonMS-Bill wrote: The United States Food and Drug Administration (FDA) yesterday granted Tysabri's supplemental Biologics License Application (sBLA) Priority Review status. This means that the review of the additional Tysabri data collected as a result of the discovery of 3 cases of oft-fatal progressive multifocal leukoencephalopathy (PML) will take at most 6 months instead of the normal period of 10 months. The significance of this, asides from the 4 month time savings, is that the FDA still seemingly considers Tysabri a potentially promising drug of great import to the multiple sclerosis community.The application was submitted on September 26, 2005, which would imply that the review would be over, and the drug potentially back on the market, by the end of March, 2006."We believe that the acceptance of the sBLA for Priority Review is another step in our ongoing commitment to provide TYSABRI as a treatment option for MS patients in need," said Lars Ekman, MD, executive vice president and president, Research & Development, Elan. "We will continue to work closely with the FDA as they review the filing so that TYSABRI can be made available with an appropriate benefit-risk profile." Sharon (MSersLife creator/owner) “One minute it's a giant cabbage and the next, ka-boom! You've got cole slaw all over you." V.R. , Palmer, Alaska, where Cabbages grow huge Yahoo! Photos Ring in the New Year with Photo Calendars. Add photos, events, holidays, whatever. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 23, 2005 Report Share Posted December 23, 2005 Hi Sharon after I have heard good reports about how it has helped people yes I do want to use it when they make it available again. I asked my neurologist recently about it and he was surprised it was pulled because of the good results people were getting from it. He said it will be back. I will be in line when it comes back. Bill Sharon Marsden wrote: > Thanks so much, Bill, that sending that information. Tysabri is the > drug my neuro said he really wanted me to " seriously consider " . > What about you? Are you also thinking about it? > Sharon > > */MS-Bill /* wrote: > > > The United States Food and Drug Administration (FDA) yesterday > granted > Tysabri's supplemental Biologics License Application (sBLA) Priority > Review status. This means that the review of the additional > Tysabri data > collected as a result of the discovery of 3 cases of oft-fatal > progressive multifocal leukoencephalopathy (PML) will take at most 6 > months instead of the normal period of 10 months. The significance of > this, asides from the 4 month time savings, is that the FDA still > seemingly considers Tysabri a potentially promising drug of great > import > to the multiple sclerosis community. > > The application was submitted on September 26, 2005, which would > imply > that the review would be over, and the drug potentially back on the > market, by the end of March, 2006. > > " We believe that the acceptance of the sBLA for Priority Review is > another step in our ongoing commitment to provide TYSABRI as a > treatment > option for MS patients in need, " said Lars Ekman, MD, executive vice > president and president, Research & Development, Elan. " We will > continue > to work closely with the FDA as they review the filing so that > TYSABRI > can be made available with an appropriate benefit-risk profile. " > > > > > *_Sharon_ (MSersLife creator/owner) * > *“One minute it's a giant cabbage and the next, ka-boom! You've got > cole slaw all over you. " * V.R. , Palmer, Alaska, where > Cabbages grow /huge/ > > ------------------------------------------------------------------------ > Yahoo! Photos > Ring in the New Year with Photo Calendars > <http://us.rd.yahoo.com/mail_us/taglines/photos/*http://pg.photos.yahoo.com/ph//\ page?.file=calendar_splash.html & .dir=>. > Add photos, events, holidays, whatever. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 23, 2005 Report Share Posted December 23, 2005 Hi Bill: I feel the same way. (I think) I know Darlene thinks it great and swears by it. I'm going to see my original neuro in January (the one who dxed me) and see what he says about it also. I just want to get another opinion from some I trust, you know? It's a big decision. So how are you doing Bill? Do you have ups and downs or do you feel like you are just steadily getting worse? hugs))) Sharon MS-Bill wrote: Hi Sharon after I have heard good reports about how it has helped people yes I do want to use it when they make it available again. I asked my neurologist recently about it and he was surprised it was pulled because of the good results people were getting from it. He said it will be back. I will be in line when it comes back.BillSharon Marsden wrote:> Thanks so much, Bill, that sending that information. Tysabri is the > drug my neuro said he really wanted me to "seriously consider".> What about you? Are you also thinking about it?> Sharon>> */MS-Bill /* wrote:>>> The United States Food and Drug Administration (FDA) yesterday> granted> Tysabri's supplemental Biologics License Application (sBLA) Priority> Review status. This means that the review of the additional> Tysabri data> collected as a result of the discovery of 3 cases of oft-fatal> progressive multifocal leukoencephalopathy (PML) will take at most 6> months instead of the normal period of 10 months. The significance of> this, asides from the 4 month time savings, is that the FDA still> seemingly considers Tysabri a potentially promising drug of great> import> to the multiple sclerosis community.>> The application was submitted on September 26, 2005, which would> imply> that the review would be over, and the drug potentially back on the> market, by the end of March, 2006.>> "We believe that the acceptance of the sBLA for Priority Review is> another step in our ongoing commitment to provide TYSABRI as a> treatment> option for MS patients in need," said Lars Ekman, MD, executive vice> president and president, Research & Development, Elan. "We will> continue> to work closely with the FDA as they review the filing so that> TYSABRI> can be made available with an appropriate benefit-risk profile.">>>>> *_Sharon_ (MSersLife creator/owner) *> *“One minute it's a giant cabbage and the next, ka-boom! You've got > cole slaw all over you."* V.R. , Palmer, Alaska, where > Cabbages grow /huge/>> ------------------------------------------------------------------------> Yahoo! Photos> Ring in the New Year with Photo Calendars > . > Add photos, events, holidays, whatever.>> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2005 Report Share Posted December 24, 2005 I am doing well I still have my double vision since this past summer. It has improved a lot though and I am hoping it will someday go away. I don't really enjoy having to use my eye patch much so when I drive I keep my patch handy when needed. I usely just close one eye while I drive. I hav e found if I sit certain way's my double vision goes away. I like watching TV in our room I have a way I sit to avoif the double vision. When ever we get done eating our supper I will often tell Judy jokingly I am heading off to TV land. We have our family Christmas tonight at Judy's mothers home. All of Judy's relatives get together for a meal and all opening the presents. The family keeps growing with all the kids being born. Judy's father is in the nursing home with Alzheimers and the Christmas party has never been the same since his illness. Judy's mother is in her 80's and not as strong as she use to be and I often wonder how long she will keep going on. Thanks for asking. What kind of Christmas do you have with your faamily? Bill Sharon Marsden wrote: > Hi Bill: > I feel the same way. (I think) I know Darlene thinks it great and > swears by it. I'm going to see my original neuro in January (the one > who dxed me) and see what he says about it also. I just want to get > another opinion from some I trust, you know? It's a big decision. > So how are you doing Bill? Do you have ups and downs or do you feel > like you are just steadily getting worse? > hugs))) > Sharon > > */MS-Bill /* wrote: > > Hi Sharon after I have heard good reports about how it has helped > people > yes I do want to use it when they make it available again. I asked my > neurologist recently about it and he was surprised it was pulled > because > of the good results people were getting from it. He said it will be > back. I will be in line when it comes back. > Bill > > Sharon Marsden wrote: > > > Thanks so much, Bill, that sending that information. Tysabri is the > > drug my neuro said he really wanted me to " seriously consider " . > > What about you? Are you also thinking about it? > > Sharon > > > > */MS-Bill /* wrote: > > > > > > The United States Food and Drug Administration (FDA) yesterday > > granted > > Tysabri's supplemental Biologics License Application (sBLA) Priority > > Review status. This means that the review of the additional > > Tysabri data > > collected as a result of the discovery of 3 cases of oft-fatal > > progressive multifocal leukoencephalopathy (PML) will take at most 6 > > months instead of the normal period of 10 months. The > significance of > > this, asides from the 4 month time savings, is that the FDA still > > seemingly considers Tysabri a potentially promising drug of great > > import > > to the multiple sclerosis community. > > > > The application was submitted on September 26, 2005, which would > > imply > > that the review would be over, and the drug potentially back on the > > market, by the end of March, 2006. > > > > " We believe that the acceptance of the sBLA for Priority Review is > > another step in our ongoing commitment to provide TYSABRI as a > > treatment > > option for MS patients in need, " said Lars Ekman, MD, executive vice > > president and president, Research & Development, Elan. " We will > > continue > > to work closely with the FDA as they review the filing so that > > TYSABRI > > can be made available with an appropriate benefit-risk profile. " > > > > > > > > > > *_Sharon_ (MSersLife creator/owner) * > > *“One minute it's a giant cabbage and the next, ka-boom! You've got > > cole slaw all over you. " * V.R. , Palmer, Alaska, where > > Cabbages grow /huge/ > > > > > ------------------------------------------------------------------------ > > Yahoo! Photos > > Ring in the New Year with Photo Calendars > > . > > Add photos, events, holidays, whatever. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2005 Report Share Posted December 24, 2005 The double vision must really be awful for you, Bill. I can't imagine it being there all the time. You are in my prayers. This morning we're driving up to Northern Arizona (a 4 hour drive) to spend Christmas with my daughter, Challis, and her family. We'll be there until Monday. With just my two kids, their spouses and the grandkids there will be 14 of us. My parents are both gone so I'm the "elder" in the family. Enjoy your family gathering with Judy's parents. At least you aren't the "elder"! lol SharonMS-Bill wrote: I am doing well I still have my double vision since this past summer. It has improved a lot though and I am hoping it will someday go away. I don't really enjoy having to use my eye patch much so when I drive I keep my patch handy when needed. I usely just close one eye while I drive. I hav e found if I sit certain way's my double vision goes away. I like watching TV in our room I have a way I sit to avoif the double vision. When ever we get done eating our supper I will often tell Judy jokingly I am heading off to TV land.We have our family Christmas tonight at Judy's mothers home. All of Judy's relatives get together for a meal and all opening the presents. The family keeps growing with all the kids being born. Judy's father is in the nursing home with Alzheimers and the Christmas party has never been the same since his illness. Judy's mother is in her 80's and not as strong as she use to be and I often wonder how long she will keep going on.Thanks for asking.What kind of Christmas do you have with your faamily?BillSharon Marsden wrote:> Hi Bill:> I feel the same way. (I think) I know Darlene thinks it great and > swears by it. I'm going to see my original neuro in January (the one > who dxed me) and see what he says about it also. I just want to get > another opinion from some I trust, you know? It's a big decision.> So how are you doing Bill? Do you have ups and downs or do you feel > like you are just steadily getting worse?> hugs)))> Sharon>> */MS-Bill /* wrote:>> Hi Sharon after I have heard good reports about how it has helped> people> yes I do want to use it when they make it available again. I asked my> neurologist recently about it and he was surprised it was pulled> because> of the good results people were getting from it. He said it will be> back. I will be in line when it comes back.> Bill>> Sharon Marsden wrote:>> > Thanks so much, Bill, that sending that information. Tysabri is the> > drug my neuro said he really wanted me to "seriously consider".> > What about you? Are you also thinking about it?> > Sharon> >> > */MS-Bill /* wrote:> >> >> > The United States Food and Drug Administration (FDA) yesterday> > granted> > Tysabri's supplemental Biologics License Application (sBLA) Priority> > Review status. This means that the review of the additional> > Tysabri data> > collected as a result of the discovery of 3 cases of oft-fatal> > progressive multifocal leukoencephalopathy (PML) will take at most 6> > months instead of the normal period of 10 months. The> significance of> > this, asides from the 4 month time savings, is that the FDA still> > seemingly considers Tysabri a potentially promising drug of great> > import> > to the multiple sclerosis community.> >> > The application was submitted on September 26, 2005, which would> > imply> > that the review would be over, and the drug potentially back on the> > market, by the end of March, 2006.> >> > "We believe that the acceptance of the sBLA for Priority Review is> > another step in our ongoing commitment to provide TYSABRI as a> > treatment> > option for MS patients in need," said Lars Ekman, MD, executive vice> > president and president, Research & Development, Elan. "We will> > continue> > to work closely with the FDA as they review the filing so that> > TYSABRI> > can be made available with an appropriate benefit-risk profile."> >> >> >> >> > *_Sharon_ (MSersLife creator/owner) *> > *“One minute it's a giant cabbage and the next, ka-boom! You've got> > cole slaw all over you."* V.R. , Palmer, Alaska, where> > Cabbages grow /huge/> >> >> ------------------------------------------------------------------------> > Yahoo! Photos> > Ring in the New Year with Photo Calendars> > .> > Add photos, events, holidays, whatever.> >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 24, 2005 Report Share Posted December 24, 2005 Sharon, I've been called an "Elder" in Native American gatherings, pagan gatherings, SCA events, etc...since I was in my early 30's...it is a badge of Honor hon, "elder" does NOT mean "old!" (at least I *hope* not) ave a Terrific time and a Verry Merry to All!!! (well "terrific" and "merry" have two rr's, so I figgered Very should too) Peace & Blessings,~*~Akiba~*~Pragmatic VisionaryIsis! Isis! Ra! Ra! Ra!akiba@... Re: Tysabri The double vision must really be awful for you, Bill. I can't imagine it being there all the time. You are in my prayers. This morning we're driving up to Northern Arizona (a 4 hour drive) to spend Christmas with my daughter, Challis, and her family. We'll be there until Monday. With just my two kids, their spouses and the grandkids there will be 14 of us. My parents are both gone so I'm the "elder" in the family. Enjoy your family gathering with Judy's parents. At least you aren't the "elder"! lol SharonMS-Bill wrote: I am doing well I still have my double vision since this past summer. It has improved a lot though and I am hoping it will someday go away. I don't really enjoy having to use my eye patch much so when I drive I keep my patch handy when needed. I usely just close one eye while I drive. I hav e found if I sit certain way's my double vision goes away. I like watching TV in our room I have a way I sit to avoif the double vision. When ever we get done eating our supper I will often tell Judy jokingly I am heading off to TV land.We have our family Christmas tonight at Judy's mothers home. All of Judy's relatives get together for a meal and all opening the presents. The family keeps growing with all the kids being born. Judy's father is in the nursing home with Alzheimers and the Christmas party has never been the same since his illness. Judy's mother is in her 80's and not as strong as she use to be and I often wonder how long she will keep going on.Thanks for asking.What kind of Christmas do you have with your faamily?BillSharon Marsden wrote:> Hi Bill:> I feel the same way. (I think) I know Darlene thinks it great and > swears by it. I'm going to see my original neuro in January (the one > who dxed me) and see what he says about it also. I just want to get > another opinion from some I trust, you know? It's a big decision.> So how are you doing Bill? Do you have ups and downs or do you feel > like you are just steadily getting worse?> hugs)))> Sharon>> */MS-Bill /* wrote:>> Hi Sharon after I have heard good reports about how it has helped> people> yes I do want to use it when they make it available again. I asked my> neurologist recently about it and he was surprised it was pulled> because> of the good results people were getting from it. He said it will be> back. I will be in line when it comes back.> Bill>> Sharon Marsden wrote:>> > Thanks so much, Bill, that sending that information. Tysabri is the> > drug my neuro said he really wanted me to "seriously consider".> > What about you? Are you also thinking about it?> > Sharon> >> > */MS-Bill /* wrote:> >> >> > The United States Food and Drug Administration (FDA) yesterday> > granted> > Tysabri's supplemental Biologics License Application (sBLA) Priority> > Review status. This means that the review of the additional> > Tysabri data> > collected as a result of the discovery of 3 cases of oft-fatal> > progressive multifocal leukoencephalopathy (PML) will take at most 6> > months instead of the normal period of 10 months. The> significance of> > this, asides from the 4 month time savings, is that the FDA still> > seemingly considers Tysabri a potentially promising drug of great> > import> > to the multiple sclerosis community.> >> > The application was submitted on September 26, 2005, which would> > imply> > that the review would be over, and the drug potentially back on the> > market, by the end of March, 2006.> >> > "We believe that the acceptance of the sBLA for Priority Review is> > another step in our ongoing commitment to provide TYSABRI as a> > treatment> > option for MS patients in need," said Lars Ekman, MD, executive vice> > president and president, Research & Development, Elan. "We will> > continue> > to work closely with the FDA as they review the filing so that> > TYSABRI> > can be made available with an appropriate benefit-risk profile."> >> >> >> >> > *_Sharon_ (MSersLife creator/owner) *> > *“One minute it's a giant cabbage and the next, ka-boom! You've got> > cole slaw all over you."* V.R. , Palmer, Alaska, where> > Cabbages grow /huge/> >> >> ------------------------------------------------------------------------> > Yahoo! Photos> > Ring in the New Year with Photo Calendars> > .> > Add photos, events, holidays, whatever.> >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2005 Report Share Posted December 27, 2005 I had double vision this past summer. It was one of the many symptoms I had that landed me in Rehab for a week. My PT was fresh out of school and had done a lot of study on MS. He had a little exercise for me that cleared my vision by the second time I tried it. I was so grateful I was almost crying. If you want the instructions I can try to explain it here. I don't know if you have tried them before. LMK, mae Reply-To: MSersLife To: MSersLife Subject: Re: TysabriDate: Sat, 24 Dec 2005 06:08:17 -0500>I am doing well I still have my double vision since this past summer. It>has improved a lot though and I am hoping it will someday go away. I>don't really enjoy having to use my eye patch much so when I drive I>keep my patch handy when needed. I usely just close one eye while I>drive. I hav e found if I sit certain way's my double vision goes away.>I like watching TV in our room I have a way I sit to avoif the double>vision. When ever we get done eating our supper I will often tell Judy>jokingly I am heading off to TV land.>We have our family Christmas tonight at Judy's mothers home. All of>Judy's relatives get together for a meal and all opening the presents.>The family keeps growing with all the kids being born. Judy's father is>in the nursing home with Alzheimers and the Christmas party has never>been the same since his illness. Judy's mother is in her 80's and not as>strong as she use to be and I often wonder how long she will keep going on.>Thanks for asking.>What kind of Christmas do you have with your faamily?>Bill>>Sharon Marsden wrote:>> > Hi Bill:> > I feel the same way. (I think) I know Darlene thinks it great and> > swears by it. I'm going to see my original neuro in January (the one> > who dxed me) and see what he says about it also. I just want to get> > another opinion from some I trust, you know? It's a big decision.> > So how are you doing Bill? Do you have ups and downs or do you feel> > like you are just steadily getting worse?> > hugs)))> > Sharon> >> > */MS-Bill /* wrote:> >> > Hi Sharon after I have heard good reports about how it has helped> > people> > yes I do want to use it when they make it available again. I asked my> > neurologist recently about it and he was surprised it was pulled> > because> > of the good results people were getting from it. He said it will be> > back. I will be in line when it comes back.> > Bill> >> > Sharon Marsden wrote:> >> > > Thanks so much, Bill, that sending that information. Tysabri is the> > > drug my neuro said he really wanted me to "seriously consider".> > > What about you? Are you also thinking about it?> > > Sharon> > >> > > */MS-Bill /* wrote:> > >> > >> > > The United States Food and Drug Administration (FDA) yesterday> > > granted> > > Tysabri's supplemental Biologics License Application (sBLA) Priority> > > Review status. This means that the review of the additional> > > Tysabri data> > > collected as a result of the discovery of 3 cases of oft-fatal> > > progressive multifocal leukoencephalopathy (PML) will take at most 6> > > months instead of the normal period of 10 months. The> > significance of> > > this, asides from the 4 month time savings, is that the FDA still> > > seemingly considers Tysabri a potentially promising drug of great> > > import> > > to the multiple sclerosis community.> > >> > > The application was submitted on September 26, 2005, which would> > > imply> > > that the review would be over, and the drug potentially back on the> > > market, by the end of March, 2006.> > >> > > "We believe that the acceptance of the sBLA for Priority Review is> > > another step in our ongoing commitment to provide TYSABRI as a> > > treatment> > > option for MS patients in need," said Lars Ekman, MD, executive vice> > > president and president, Research & Development, Elan. "We will> > > continue> > > to work closely with the FDA as they review the filing so that> > > TYSABRI> > > can be made available with an appropriate benefit-risk profile."> > >> > >> > >> > >> > > *_Sharon_ (MSersLife creator/owner) *> > > *“One minute it's a giant cabbage and the next, ka-boom! You've got> > > cole slaw all over you."* V.R. , Palmer, Alaska, where> > > Cabbages grow /huge/> > >> > >> > ------------------------------------------------------------------------> > > Yahoo! Photos> > > Ring in the New Year with Photo Calendars> > > .> > > Add photos, events, holidays, whatever.> > >> > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 27, 2005 Report Share Posted December 27, 2005 Hi I would like to try what he had you do. Thanks Bill Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 2, 2006 Report Share Posted January 2, 2006 Hi Bill, Sharon and all, I'm excited about Tysabri coming back on the market. Since it has been almost 6 years since I was on it, I am having to realize that I might not get any better than I am now since it might have been to long with permanent damage. When I was in the WC I had the tysabri the next month so I know it worked when I had NEW major problems.... so if the Tysabri this time takes away my symptoms that I am having now......WOW this will be the promising drug. I hope it will work for me like it did the first time, but for some reason because I have had 6 years to wait and possibly my symptoms are " old " I will have to accept that too BUT I'm gonna give it a try. I haven't been online alot and just Friday,,,,,I broke my ankle so I am out of commition for a while. Kinda hard to have balance problems then try and use crutches with a soft cast on. Have to go in to see the orthopedic/bone doc for a regular cast. Happy New Year to you all!!! Hugs Darlene Kickin Cane Covers www.canecovers.org -------------- Original message ---------------------- > Hi Bill: > > I feel the same way. (I think) I know Darlene thinks it great and swears by > it. I'm going to see my original neuro in January (the one who dxed me) and see > what he says about it also. I just want to get another opinion from some I > trust, you know? It's a big decision. > > So how are you doing Bill? Do you have ups and downs or do you feel like you > are just steadily getting worse? > > hugs))) > Sharon > > MS-Bill wrote: > Hi Sharon after I have heard good reports about how it has helped people > yes I do want to use it when they make it available again. I asked my > neurologist recently about it and he was surprised it was pulled because > of the good results people were getting from it. He said it will be > back. I will be in line when it comes back. > Bill > > Sharon Marsden wrote: > > > Thanks so much, Bill, that sending that information. Tysabri is the > > drug my neuro said he really wanted me to " seriously consider " . > > What about you? Are you also thinking about it? > > Sharon > > > > */MS-Bill /* wrote: > > > > > > The United States Food and Drug Administration (FDA) yesterday > > granted > > Tysabri's supplemental Biologics License Application (sBLA) Priority > > Review status. This means that the review of the additional > > Tysabri data > > collected as a result of the discovery of 3 cases of oft-fatal > > progressive multifocal leukoencephalopathy (PML) will take at most 6 > > months instead of the normal period of 10 months. The significance of > > this, asides from the 4 month time savings, is that the FDA still > > seemingly considers Tysabri a potentially promising drug of great > > import > > to the multiple sclerosis community. > > > > The application was submitted on September 26, 2005, which would > > imply > > that the review would be over, and the drug potentially back on the > > market, by the end of March, 2006. > > > > " We believe that the acceptance of the sBLA for Priority Review is > > another step in our ongoing commitment to provide TYSABRI as a > > treatment > > option for MS patients in need, " said Lars Ekman, MD, executive vice > > president and president, Research & Development, Elan. " We will > > continue > > to work closely with the FDA as they review the filing so that > > TYSABRI > > can be made available with an appropriate benefit-risk profile. " > > > > > > > > > > *_Sharon_ (MSersLife creator/owner) * > > *“One minute it's a giant cabbage and the next, ka-boom! You've got > > cole slaw all over you. " * V.R. , Palmer, Alaska, where > > Cabbages grow /huge/ > > > > ------------------------------------------------------------------------ > > Yahoo! Photos > > Ring in the New Year with Photo Calendars > > . > > Add photos, events, holidays, whatever. > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 2, 2006 Report Share Posted January 2, 2006 I would be more thrilled about it if Medicare part D were going to actually pay for it! Cheers! n Re: Tysabri Hi Bill, Sharon and all,I'm excited about Tysabri coming back on the market. Since it has been almost 6 years since I was on it, I am having to realize that I might not get any better than I am now since it might have been to long with permanent damage. When I was in the WC I had the tysabri the next month so I know it worked when I had NEW major problems.... so if the Tysabri this time takes away my symptoms that I am having now......WOW this will be the promising drug. I hope it will work for me like it did the first time, but for some reason because I have had 6 years to wait and possibly my symptoms are "old" I will have to accept that too BUT I'm gonna give it a try. I haven't been online alot and just Friday,,,,,I broke my ankle so I am out of commition for a while. Kinda hard to have balance problems then try and use crutches with a soft cast on. Have to go in to see the orthopedic/bone doc for a regular cast. Happy New Year to you all!!!HugsDarleneKickin Cane Coverswww.canecovers.org-------------- Original message ----------------------> Hi Bill:> > I feel the same way. (I think) I know Darlene thinks it great and swears by > it. I'm going to see my original neuro in January (the one who dxed me) and see > what he says about it also. I just want to get another opinion from some I > trust, you know? It's a big decision. > > So how are you doing Bill? Do you have ups and downs or do you feel like you > are just steadily getting worse? > > hugs)))> Sharon> > MS-Bill wrote:> Hi Sharon after I have heard good reports about how it has helped people > yes I do want to use it when they make it available again. I asked my > neurologist recently about it and he was surprised it was pulled because > of the good results people were getting from it. He said it will be > back. I will be in line when it comes back.> Bill> > Sharon Marsden wrote:> > > Thanks so much, Bill, that sending that information. Tysabri is the > > drug my neuro said he really wanted me to "seriously consider".> > What about you? Are you also thinking about it?> > Sharon> >> > */MS-Bill /* wrote:> >> >> > The United States Food and Drug Administration (FDA) yesterday> > granted> > Tysabri's supplemental Biologics License Application (sBLA) Priority> > Review status. This means that the review of the additional> > Tysabri data> > collected as a result of the discovery of 3 cases of oft-fatal> > progressive multifocal leukoencephalopathy (PML) will take at most 6> > months instead of the normal period of 10 months. The significance of> > this, asides from the 4 month time savings, is that the FDA still> > seemingly considers Tysabri a potentially promising drug of great> > import> > to the multiple sclerosis community.> >> > The application was submitted on September 26, 2005, which would> > imply> > that the review would be over, and the drug potentially back on the> > market, by the end of March, 2006.> >> > "We believe that the acceptance of the sBLA for Priority Review is> > another step in our ongoing commitment to provide TYSABRI as a> > treatment> > option for MS patients in need," said Lars Ekman, MD, executive vice> > president and president, Research & Development, Elan. "We will> > continue> > to work closely with the FDA as they review the filing so that> > TYSABRI> > can be made available with an appropriate benefit-risk profile."> >> >> >> >> > *_Sharon_ (MSersLife creator/owner) *> > *“One minute it's a giant cabbage and the next, ka-boom! You've got > > cole slaw all over you."* V.R. , Palmer, Alaska, where > > Cabbages grow /huge/> >> > ------------------------------------------------------------------------> > Yahoo! Photos> > Ring in the New Year with Photo Calendars > > . > > Add photos, events, holidays, whatever.> >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2006 Report Share Posted January 3, 2006 Awww.... Darlene! I'm so sorry to hear about your ankle. How did that happen? When do you see the orthopedic doc? Ankle breaks are touchy. Did you break one of the bones or all three? I didn't realize it was so long ago you were on Tysabri. I thought you were on it when it was removed from the market. So you were in the original study then? hugs))) Sharonkickincanes@... wrote: Hi Bill, Sharon and all,I'm excited about Tysabri coming back on the market. Since it has been almost 6 years since I was on it, I am having to realize that I might not get any better than I am now since it might have been to long with permanent damage. When I was in the WC I had the tysabri the next month so I know it worked when I had NEW major problems.... so if the Tysabri this time takes away my symptoms that I am having now......WOW this will be the promising drug. I hope it will work for me like it did the first time, but for some reason because I have had 6 years to wait and possibly my symptoms are "old" I will have to accept that too BUT I'm gonna give it a try. I haven't been online alot and just Friday,,,,,I broke my ankle so I am out of commition for a while. Kinda hard to have balance problems then try and use crutches with a soft cast on. Have to go in to see the orthopedic/bone doc for a regular cast. Happy New Year to you all!!!HugsDarleneKickin Cane Coverswww.canecovers.org-------------- Original message ----------------------From: Sharon Marsden > Hi Bill:> > I feel the same way. (I think) I know Darlene thinks it great and swears by > it. I'm going to see my original neuro in January (the one who dxed me) and see > what he says about it also. I just want to get another opinion from some I > trust, you know? It's a big decision. > > So how are you doing Bill? Do you have ups and downs or do you feel like you > are just steadily getting worse? > > hugs)))> Sharon> > MS-Bill wrote:> Hi Sharon after I have heard good reports about how it has helped people > yes I do want to use it when they make it available again. I asked my > neurologist recently about it and he was surprised it was pulled because > of the good results people were getting from it. He said it will be > back. I will be in line when it comes back.> Bill> > Sharon Marsden wrote:> > > Thanks so much, Bill, that sending that information. Tysabri is the > > drug my neuro said he really wanted me to "seriously consider".> > What about you? Are you also thinking about it?> > Sharon> >> > */MS-Bill /* wrote:> >> >> > The United States Food and Drug Administration (FDA) yesterday> > granted> > Tysabri's supplemental Biologics License Application (sBLA) Priority> > Review status. This means that the review of the additional> > Tysabri data> > collected as a result of the discovery of 3 cases of oft-fatal> > progressive multifocal leukoencephalopathy (PML) will take at most 6> > months instead of the normal period of 10 months. The significance of> > this, asides from the 4 month time savings, is that the FDA still> > seemingly considers Tysabri a potentially promising drug of great> > import> > to the multiple sclerosis community.> >> > The application was submitted on September 26, 2005, which would> > imply> > that the review would be over, and the drug potentially back on the> > market, by the end of March, 2006.> >> > "We believe that the acceptance of the sBLA for Priority Review is> > another step in our ongoing commitment to provide TYSABRI as a> > treatment> > option for MS patients in need," said Lars Ekman, MD, executive vice> > president and president, Research & Development, Elan. "We will> > continue> > to work closely with the FDA as they review the filing so that> > TYSABRI> > can be made available with an appropriate benefit-risk profile."> >> >> >> >> > *_Sharon_ (MSersLife creator/owner) *> > *“One minute it's a giant cabbage and the next, ka-boom! You've got > > cole slaw all over you."* V.R. , Palmer, Alaska, where > > Cabbages grow /huge/> >> > ------------------------------------------------------------------------> > Yahoo! Photos> > Ring in the New Year with Photo Calendars > > . > > Add photos, events, holidays, whatever.> >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2006 Report Share Posted January 3, 2006 Since it's an infusion I thought Medicare would pay. But I guess that would be under the old rules and now that it's NEW AND IMPROVED MEDICARE it won't pay for hardly anything. I am not too thrilled with the new Medicare Part D and I can tell you aren't either, n. Sharonn Rojas wrote: I would be more thrilled about it if Medicare part D were going to actually pay for it! Cheers! n Re: Tysabri Hi Bill, Sharon and all,I'm excited about Tysabri coming back on the market. Since it has been almost 6 years since I was on it, I am having to realize that I might not get any better than I am now since it might have been to long with permanent damage. When I was in the WC I had the tysabri the next month so I know it worked when I had NEW major problems.... so if the Tysabri this time takes away my symptoms that I am having now......WOW this will be the promising drug. I hope it will work for me like it did the first time, but for some reason because I have had 6 years to wait and possibly my symptoms are "old" I will have to accept that too BUT I'm gonna give it a try. I haven't been online alot and just Friday,,,,,I broke my ankle so I am out of commition for a while. Kinda hard to have balance problems then try and use crutches with a soft cast on. Have to go in to see the orthopedic/bone doc for a regular cast. Happy New Year to you all!!!HugsDarleneKickin Cane Coverswww.canecovers.org-------------- Original message ----------------------> Hi Bill:> > I feel the same way. (I think) I know Darlene thinks it great and swears by > it. I'm going to see my original neuro in January (the one who dxed me) and see > what he says about it also. I just want to get another opinion from some I > trust, you know? It's a big decision. > > So how are you doing Bill? Do you have ups and downs or do you feel like you > are just steadily getting worse? > > hugs)))> Sharon> > MS-Bill wrote:> Hi Sharon after I have heard good reports about how it has helped people > yes I do want to use it when they make it available again. I asked my > neurologist recently about it and he was surprised it was pulled because > of the good results people were getting from it. He said it will be > back. I will be in line when it comes back.> Bill> > Sharon Marsden wrote:> > > Thanks so much, Bill, that sending that information. Tysabri is the > > drug my neuro said he really wanted me to "seriously consider".> > What about you? Are you also thinking about it?> > Sharon> >> > */MS-Bill /* wrote:> >> >> > The United States Food and Drug Administration (FDA) yesterday> > granted> > Tysabri's supplemental Biologics License Application (sBLA) Priority> > Review status. This means that the review of the additional> > Tysabri data> > collected as a result of the discovery of 3 cases of oft-fatal> > progressive multifocal leukoencephalopathy (PML) will take at most 6> > months instead of the normal period of 10 months. The significance of> > this, asides from the 4 month time savings, is that the FDA still> > seemingly considers Tysabri a potentially promising drug of great> > import> > to the multiple sclerosis community.> >> > The application was submitted on September 26, 2005, which would> > imply> > that the review would be over, and the drug potentially back on the> > market, by the end of March, 2006.> >> > "We believe that the acceptance of the sBLA for Priority Review is> > another step in our ongoing commitment to provide TYSABRI as a> > treatment> > option for MS patients in need," said Lars Ekman, MD, executive vice> > president and president, Research & Development, Elan. "We will> > continue> > to work closely with the FDA as they review the filing so that> > TYSABRI> > can be made available with an appropriate benefit-risk profile."> >> >> >> >> > *_Sharon_ (MSersLife creator/owner) *> > *“One minute it's a giant cabbage and the next, ka-boom! You've got > > cole slaw all over you."* V.R. , Palmer, Alaska, where > > Cabbages grow /huge/> >> > ------------------------------------------------------------------------> > Yahoo! Photos> > Ring in the New Year with Photo Calendars > > . > > Add photos, events, holidays, whatever.> >> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 7, 2006 Report Share Posted January 7, 2006 I hear ya there!!!!! Darlene Kickin Cane Covers www.canecovers.org --------- Re: Tysabri > > > Hi Bill, Sharon and all, > I'm excited about Tysabri coming back on the market. Since it has been almost > 6 years since I was on it, I am having to realize that I might not get any > better than I am now since it might have been to long with permanent damage. > When I was in the WC I had the tysabri the next month so I know it worked when I > had NEW major problems.... so if the Tysabri this time takes away my symptoms > that I am having now......WOW this will be the promising drug. I hope it will > work for me like it did the first time, but for some reason because I have had 6 > years to wait and possibly my symptoms are " old " I will have to accept that too > BUT I'm gonna give it a try. I haven't been online alot and just Friday,,,,,I > broke my ankle so I am out of commition for a while. Kinda hard to have balance > problems then try and use crutches with a soft cast on. Have to go in to see > the orthopedic/bone doc for a regular cast. Happy New Year to you all!!! > Hugs > Darlene > Kickin Cane Covers > www.canecovers.org > > -------------- Original message ---------------------- > > > Hi Bill: > > > > I feel the same way. (I think) I know Darlene thinks it great and swears > by > > it. I'm going to see my original neuro in January (the one who dxed me) and > see > > what he says about it also. I just want to get another opinion from some I > > trust, you know? It's a big decision. > > > > So how are you doing Bill? Do you have ups and downs or do you feel like > you > > are just steadily getting worse? > > > > hugs))) > > Sharon > > > > MS-Bill wrote: > > Hi Sharon after I have heard good reports about how it has helped people > > yes I do want to use it when they make it available again. I asked my > > neurologist recently about it and he was surprised it was pulled because > > of the good results people were getting from it. He said it will be > > back. I will be in line when it comes back. > > Bill > > > > Sharon Marsden wrote: > > > > > Thanks so much, Bill, that sending that information. Tysabri is the > > > drug my neuro said he really wanted me to " seriously consider " . > > > What about you? Are you also thinking about it? > > > Sharon > > > > > > */MS-Bill /* wrote: > > > > > > > > > The United States Food and Drug Administration (FDA) yesterday > > > granted > > > Tysabri's supplemental Biologics License Application (sBLA) Priority > > > Review status. This means that the review of the additional > > > Tysabri data > > > collected as a result of the discovery of 3 cases of oft-fatal > > > progressive multifocal leukoencephalopathy (PML) will take at most 6 > > > months instead of the normal period of 10 months. The significance of > > > this, asides from the 4 month time savings, is that the FDA still > > > seemingly considers Tysabri a potentially promising drug of great > > > import > > > to the multiple sclerosis community. > > > > > > The application was submitted on September 26, 2005, which would > > > imply > > > that the review would be over, and the drug potentially back on the > > > market, by the end of March, 2006. > > > > > > " We believe that the acceptance of the sBLA for Priority Review is > > > another step in our ongoing commitment to provide TYSABRI as a > > > treatment > > > option for MS patients in need, " said Lars Ekman, MD, executive vice > > > president and president, Research & Development, Elan. " We will > > > continue > > > to work closely with the FDA as they review the filing so that > > > TYSABRI > > > can be made available with an appropriate benefit-risk profile. " > > > > > > > > > > > > > > > *_Sharon_ (MSersLife creator/owner) * > > > * " One minute it's a giant cabbage and the next, ka-boom! You've got > > > cole slaw all over you. " * V.R. , Palmer, Alaska, where > > > Cabbages grow /huge/ > > > > > > ------------------------------------------------------------------------ > > > Yahoo! Photos > > > Ring in the New Year with Photo Calendars > > > . > > > Add photos, events, holidays, whatever. > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 17, 2006 Report Share Posted January 17, 2006 Hi Sharon, Yeah, It happened since I was thrilled to be coming home from a vacation and my hubby and daughter and I were walking up the driveway to our house and we have some stairs in the front. I went up 3 steps and lost my balance. Well, it happened so fast, next thing I know I was on the concrete cement slab. This happened on the 30th, Had to wait for the swelling and saw the doc a week later. I just saw him again on Last Friday. They took exrays and yes, I only broke 1 of the 3 ankle bones, thank goodness. I'm doing better now, that it has been over 3 1/2 weeks and am able to but some weight on it. In regards to the Tysabri, I was on the Phase II (2000) Study with 214 patients throughout the world. I don't know how to do a link to that particular study but the results were very good. Yes, I was just getting ready to go back on it when it was finnally FDA approved but 3 days later is when it was pulled. I just went to my Neuoro Friday and I will email the group with some info in regards to the Rebif and the Tysabri. I'm currently been taking the Rebif since the Study in 2000 and the Rebif has been good for me but I will be swithching if the Tysabri is approved, OK, I best get to bed, my hubby just got done taking a shower and he is coming down to "spot" me so I have no more balance accidents. Ha Ha. Talk to ya all tomorrow. Hugs Darlene Kickin Cane Covers www.canecovers.org -- [Norton AntiSpam] Re: Tysabri Awww.... Darlene! I'm so sorry to hear about your ankle. How did that happen? When do you see the orthopedic doc? Ankle breaks are touchy. Did you break one of the bones or all three? I didn't realize it was so long ago you were on Tysabri. I thought you were on it when it was removed from the market. So you were in the original study then? hugs))) Sharonkickincanes@... wrote: Hi Bill, Sharon and all,I'm excited about Tysabri coming back on the market. Since it has been almost 6 years since I was on it, I am having to realize that I might not get any better than I am now since it might have been to long with permanent damage. When I was in the WC I had the tysabri the next month so I know it worked when I had NEW major problems.... so if the Tysabri this time takes away my symptoms that I am having now......WOW this will be the promising drug. I hope it will work for me like it did the first time, but for some reason because I have had 6 years to wait and possibly my symptoms are "old" I will have to accept that too BUT I'm gonna give it a try. I haven't been online alot and just Friday,,,,,I broke my ankle so I am out of commition for a while. Kinda hard to have balance problems then try and use crutches with a soft cast on. Have to go in to see the orthopedic/bone doc for a regular cast. Happy New Year to you all!!!HugsDarleneKickin Cane Coverswww.canecovers.org-------------- Original message ----------------------> Hi Bill:> > I feel the same way. (I think) I know Darlene thinks it great and swears by > it. I'm going to see my original neuro in January (the one who dxed me) and see > what he says about it also. I just want to get another opinion from some I > trust, you know? It's a big decision. > > So how are you doing Bill? Do you have ups and downs or do you feel like you > are just steadily getting worse? > > hugs)))> Sharon> > MS-Bill wrote:> Hi Sharon after I have heard good reports about how it has helped people > yes I do want to use it when they make it available again. I asked my > neurologist recently about it and he was surprised it was pulled because > of the good results people were getting from it. He said it will be > back. I will be in line when it comes back.> Bill> > Sharon Marsden wrote:> > > Thanks so much, Bill, that sending that information. Tysabri is the > > drug my neuro said he really wanted me to "seriously consider".> > What about you? Are you also thinking about it?> > Sharon> >> > */MS-Bill /* wrote:> >> >> > The United States Food and Drug Administration (FDA) yesterday> > granted> > Tysabri's supplemental Biologics License Application (sBLA) Priority> > Review status. This means that the review of the additional> > Tysabri data> > collected as a result of the discovery of 3 cases of oft-fatal> > progressive multifocal leukoencephalopathy (PML) will take at most 6> > months instead of the normal period of 10 months. The significance of> > this, asides from the 4 month time savings, is that the FDA still> > seemingly considers Tysabri a potentially promising drug of great> > import> > to the multiple sclerosis community.> >> > The application was submitted on September 26, 2005, which would> > imply> > that the review would be over, and the drug potentially back on the> > market, by the end of March, 2006.> >> > "We believe that the acceptance of the sBLA for Priority Review is> > another step in our ongoing commitment to provide TYSABRI as a> > treatment> > option for MS patients in need," said Lars Ekman, MD, executive vice> > president and president, Research & Development, Elan. "We will> > continue> > to work closely with the FDA as they review the filing so that> > TYSABRI> > can be made available with an appropriate benefit-risk profile."> >> >> >> >> > *_Sharon_ (MSersLife creator/owner) *> > *“One minute it's a giant cabbage and the next, ka-boom! You've got > > cole slaw all over you."* V.R. , Palmer, Alaska, where > > Cabbages grow /huge/> >> > ------------------------------------------------------------------------> > Yahoo! Photos> > Ring in the New Year with Photo Calendars > > . > > Add photos, events, holidays, whatever.> >> > Quote Link to comment Share on other sites More sharing options...
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