Here is what I have found so far. Appears my biggest mistake is taking too many Anitcholergenics meds. No wonder my stomach quit functioning. What was I thinking? Combivent, took it to open throat to breath - Ipratropium is a derivative of atropine

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Here is what I have found so far. Appears my biggest mistake is taking too many Anitcholergenics meds. No wonder my stomach quit functioning. What was I thinking? Combivent, took it to open throat to breath - Ipratropium is a derivative of atropine,

anticholergenic Benedryl, Took it for my bloating - thinking it was allergies to foods it is Diphenhydramine, antihistamine, anticholergenic

NiQuil, Too it to sleep and clear up sinuses - Doxylamine, antihistamine, anticholergenic Pantanase - Took to clear sinuses - Olopatadine

hydrochloride, anithistamine and anticholergenic

Clonazapam Antianxiety took it for anxiety from being sick, benzodiazepines Omeprazole, this did not work all for me Pulmicort Duo Neb, Ipratropium is a derivative of atropine, anticholergenicNo wonder I was having so many problems.

I have been doing serious rinsing after Spiriva and Pulmicort so as little as possible makes it to my stomach. Below is some of the info I found looking around. Lynne

What causes

gastroparesis?

The

most common cause of gastroparesis is diabetes. People with diabetes have high

blood glucose, also called blood sugar, which in turn causes chemical changes

in nerves and damages the blood vessels that carry oxygen and nutrients to the

nerves. Over time, high blood glucose can damage the vagus nerve.

Some

other causes of gastroparesis are

·

surgery on the stomach

or vagus nerve

·

viral infections

·

anorexia nervosa or

bulimia

·

medications—anticholinergics

and narcotics—that slow contractions in the intestine

·

gastroesophageal

reflux disease

·

smooth muscle

disorders, such as amyloidosis and scleroderma

·

nervous system

diseases, including abdominal migraine and Parkinson's disease

·

metabolic disorders,

including hypothyroidism

Many

people have what is called idiopathic gastroparesis, meaning the cause is

unknown and cannot be found even after medical tests.

http://digestive.niddk.nih.gov/ddiseases/pubs/gastroparesis/

What causes gastroparesis?

The cause is not known, but gastroparesis is a common complication of Type 1

insulin-dependent diabetes occuring in about 20% of patients - especially in

those who have developed other signs of nerve damage (diabetic neuropathy) such

as numbness or burning of the feet. People with Type 2 diabetes get it also,

but less often. Diabetic gastroparesis can be a vicious cycle since diabetes

causes nerve damage which leads to gastroparesis. And gastroparesis can worsen

diabetic control since delayed stomach emptying makes digestion unpredictable

which results in uneven blood sugar levels. Gastroparesis may also be a

complication of stomach surgery for ulcer disease or weight loss. Some systemic

disorders such as kidney failure, lupus, Parkinson's disease, sclerodema, and

thyroid disorders can also delay gastric emptying. Up to 30% of individuals

with gastroparesis are idiopathic,

meaning that there is no identifiable cause. It is felt that some of these may

be due to an acute viral infection. Lastly, some medications such as

anticholinergics (antispasmodics) can worsen the situation.

http://www.gihealth.com/html/education/gastroparesis.html

Agents with anticholinergic properties

are as follows:

·

Anticholinergics

o

Atropine, scopolamine, Ipratropium is a derivative of atropine

o

Glycopyrrolate

o

Benztropine, trihexyphenidyl

·

Antihistamines

o

Chlorpheniramine

o

Cyproheptadine

o

Doxylamine NiQuil

o

Hydroxyzine

o

Dimenhydrinate,

o

Diphenhydramine benedryl

o

Meclizine

o

Promethazine

·

Antipsychotics

o

Chlorpromazine

o

Clozapine

o

Mesoridazine

o

Olanzapine

o

Quetiapine

o

Thioridazine

·

Antispasmodics

o

Clidinium

o

Dicyclomine

o

Hyoscyamine

o

Oxybutynin

o

Propantheline

·

Cyclic antidepressants

o

Amitriptyline

o

Amoxapine

o

Clomipramine

o

Desipramine

o

Doxepin

o

Imipramine

o

Nortriptyline

o

Protriptyline

·

Mydriatics

o

Cyclopentolate

o

Homatropine

o

Tropicamide

·

Plants

o

Amanita muscaria (fly agaric)

o

Amanita pantherina (panther mushroom)

o

Arctium lappa (burdock root)

o

Atropa belladonna (deadly

nightshade)

o

Cestrum nocturnum (night blooming jessamine)

o

Datura suaveolens (angel's

trumpet)

o

Datura stramonium (jimson

weed)

o

Hyoscyamus niger (black

henbane)

o

Lantana camara (red sage)

o

Solanum carolinensis (wild tomato)

o

Solanum dulcamara (bittersweet)

o

Solanum pseudocapsicum (Jerusalem cherry)

o

Solanum tuberosum (potato)

o

Miscellaneous, including carbamazepine, cyclobenzaprine, and orphenadrine

To: asthma Sent: Friday, January 20, 2012 1:29 PM Subject: Re: ipratropium bromide

Hi Lynne et al,

Regarding the ipratropium nebs, I have noticed lately during a very bad month that included two admissions into hospital, that my bloating and stomach discomfort had increased! I initially put it down to the high dose of prednisolone and the constant antibiotics, however reading your comments reminded me that I had heard that ipratropium can cause certain digestion problems.

I have been on ipratropium nebs constantly and in some quantity since the beginning of December, funny but that's when my bloating reappeared! So maybe I need to examine the need for ipratropium and weigh the benefits against the side effect?

As for tiotropium or Spivira, I used this for years until it appeared to become in affective. When I spoke to my GP about it, she suggested that some of us who produce lots of mucus, phlegm or sputum, what ever you wish to call the stuff, may have some difficulty in absorbing the spivira powder as it can stick to the mucus instead of being absorbed into the tissue.

So, ipratropium nebuliser or tiotropium spivira? Any advice anyone? Facts not personal views would be appreciated as we are all different and what may work for one will not work for another.

many thanks

Cheers from Mike (Chip) Chapman

Cornwall. UK

Subject: Re: Reflux, asthma or both? iptatroprium bromideTo: "asthma " <asthma >Date: Friday, 20 January, 2012, 16:43

Madeline, what med are you using to replace the iptatroprium bromide? I hope you are feeling better.

I was on Combivent for about 6 months.

They kept trying to tell me I had relfux but none of the reflux meds really helped. I never had

reflux before I started the iptatroprium bromide (I also used it in neb the duo neb mixture).

My doctors did not make the connection, I did thanks to this board! I stopped taking the

Combivent switched to the Spiriva on my own.

For some reason I am not having the stomach issues with the Spiriva.

My belching and bloating has stopped. I actually had attacks where my stomach would bloat,

I would burp, regurgitate, no be able to breath, my face, neck and chest would flush.

My stomach is slowly returning to normal I can eat almost everything I was able to before.

Although I think my migraine meds (midrin and fiorinol) make my stomach symptoms worse.

One thing I did notice when I was having stomach issues it seemed to worsen my breathing.

Lynne

To: "asthma " <asthma > Sent: Thursday, January 19, 2012 8:39 PMSubject: Re: Reflux, asthma or both?

Hi lady. Is he taking Atrovent (iptatroprium bromide) or Spiriva? Is he complaining of nausea or vomiting? While reflux can worsen asthma symptoms, another lesser looked at issue is gastroparesis. The only reason this comes to mind is that I have recently been diagnosed with gastroparesis. Atrovent, Spiriva, and any other drug that works by relaxing smooth muscle walls can cause this. Belching is a common symptom of gastroparesis while it is not generally associated with GERD. Not wanting to cloud the issue, but it is a possible cause.

Madeline

To: asthma Sent: Wednesday, January 18, 2012 9:11 AMSubject: Reflux, asthma or both?

My nine year old has had a worsening of his asthma in the past two months. Started with a virus that triggered a bad flare. Doctor started him on inhaled corticosteroids which seems to be helping some but not enough. He's having allergy testing in two weeks since it's been a long time since he's been tested. We'll see if anything new comes up. With the past several attacks during the night, he is burping a few times after the attack is over. Does this sound like reflux, or is he burping from overinflated lungs pressing on stomach? I have never had burping with asthma attacks myself. Of course, I will discuss this with his doctor too.