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thimerosal & mito: UC study finds children with autism have mitochondrial dysfunction

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1. Thimerosal induces neuronal cell apoptosis by causing cytochrome c

and apoptosis-inducing factor release from mitochondria.

<http://www.ncbi.nlm.nih.gov/pubmed/16273274>

Yel L, Brown LE, Su K, Gollapudi S, Gupta S.

Int J Mol Med. 2005 Dec;16(6):971-7.PMID: 16273274

2. Mitochondrial mediated thimerosal-induced apoptosis in a human

neuroblastoma cell line (SK-N-SH).

<http://www.ncbi.nlm.nih.gov/pubmed/15869795>

Humphrey ML, Cole MP, Pendergrass JC, Kiningham KK.

Neurotoxicology. 2005 Jun;26(3):407-16.PMID: 15869795

3. Biochemical and molecular basis of thimerosal-induced apoptosis in T

cells: a major role of mitochondrial pathway.

<http://www.ncbi.nlm.nih.gov/pubmed/12140745>

Makani S, Gollapudi S, Yel L, Chiplunkar S, Gupta S.

Genes Immun. 2002 Aug;3(5):270-8.PMID: 12140745

4. Cellular and mitochondrial glutathione redox imbalance in

lymphoblastoid cells derived from children with autism.

<http://www.ncbi.nlm.nih.gov/pubmed/19307255>

SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, Gaylor DW.

FASEB J. 2009 Aug;23(8):2374-83.

5. Developmental regression and mitochondrial dysfunction in a child

with autism. <http://www.ncbi.nlm.nih.gov/pubmed/16566887>

Poling JS, Frye RE, Shoffner J, Zimmerman AW.

J Child Neurol. 2006 Feb;21(2):170-2.PMID: 16566887

> UC study finds children with *autism* have mitochondrial

> dysfunction

> <http://www.eurekalert.org/pub_releases/2010-11/uoc--uds112410.php>

> EurekAlert (press release) -

> http://www.eurekalert.org/pub_releases/2010-11/uoc--uds112410.php

>

> Evidence of *mitochondrial dysfunction *in autism and ...

>

<http://hstrial-astephens3.homestead.com/Evidence_of_Mitochondrial_Dysfunction_i\

n_Autism_and_Implications_for_Treatment.pdf>

>

>

>

> Biomarker-guided interventions of clinically relevant conditions

> associated with autism spectrum disorders and attention deficit

> hyperactivity disorder. <http://www.ncbi.nlm.nih.gov/pubmed/20359266>

> Bradstreet JJ, S, Baral M, Rossignol DA.

> Altern Med Rev. 2010 Apr;15(1):15-32. Review.

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