fwd: BPA-induced epigenetic change; evidence BPA affects germ line

[Guest guest]

fwd:

The following two BPA studies might be of interest - I don't think

either of these came across the CHE lists.

BPA-induces epigenetic changes resulting in oestrogen hypersensitivity

<http://www.fasebj.org/cgi/content/abstract/fj.09-140533v1>:

Prenatal BPA exposure caused mice in this study to exhibit uterine

hypersensitivity to oestrogen throughout adulthood, indicating

long-lasting epigenetic changes to developmental programming.

Perinatal exposure of rats to BPA affects fertility of male offspring

<http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B6T99-4XG3SK6-1 & _user=\

10 & _coverDate=11/18/2009 & _rdoc=1 & _fmt=high & _orig=search & _sort=d & _docanchor= & view\

=c & _acct=C000050221 & _version=1 & _urlVersion=0 & _userid=10 & md5=edbc37b2a282845d1f87\

ff55f0a13aad>:

Rat study showing that exposure to BPA at levels within the range of

human exposure lowers male fertility in adulthood and affects the germ

line, also reducing the fertility of offspring.

We have also put together a piece on the *limitations of toxicology* for

dealing with low doses of endocrine disruptors in this month's /Health &

Environment/...

http://healthandenvironmentonline.com/issue-24-toxicology/

Best wishes,

* Whaley*

Editor, Health & Environment

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*Web*: healthandenvironmentonline.com/

<http://healthandenvironmentonline.com/>

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/Health & Environment/: A monthly e-publication and website about

the importance of the environment as a determinant of public health.

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