mixture: BPA and soy genistein together affect CNS in rat embryos: BPA exposure in womb alters key mammary gland proteins at puberty

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* BPA and genistein together affect nervous system in rat

embryos.

<http://www.environmentalhealthnews.org/ehs/newscience/bpa-genistein-mix-alter-n\

ervous-system-development/>

* 14 May 2010

A mixture of two common substances often found in food --

bisphenol A and the soy phystoestrogen genistein -- caused more

serious developmental problems in rat embryos than would be

expected from either one alone. While BPA and genistein each

inhibited some aspects of the embryos' growth, the combined

exposures caused more severe problems. Together, they caused

malformations and defects the the rats' central nervous system,

including the brain.

BPA exposure in the womb alters key mammary gland proteins at puberty.

<http://www.environmentalhealthnews.org/ehs/newscience/prenatal-bpa-changes-mamm\

ary-gland-protein-expression/>

13 May 2010

A study with rats finds that exposure to low doses of BPA during

development changes some of the proteins expressed by the mammary gland

- including those that control cell proliferation and death - before and

during puberty in ways consistent with cancer formation. This is the

first time the chemical has been shown to influence key cell development

through the proteins that guide these later-life processes.