PBDEs & Thyroid Hormone during Pregnancy: hypomethylation & autism

[Guest guest]

Another co-factor in skewing neurodevelopment:

EHN synopsis:

Flame retardants can alter thyroid hormones in pregnant women, new study

shows.

<http://www.environmentalhealthnews.org/ehs/news/flame-retardants-linked-to-alte\

red-thyroid-hormones-in-pregnant-women>

By Marla Cone Environmental Health News 21 June 2010

High levels of brominated flame retardants can alter

pregnant women's thyroid hormones, which are critical to a baby's growth

and brain development, according to a California study published Monday.

The study is considered important because it is the first human research

showing a link between the ubiquitous chemicals and altered levels of

the hormones in pregnant women. The effects on babies are unknown, but

some researchers say it may lead to smaller fetuses, and reduce

childen's intelligence and motor skills...

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EHP articles:

Polybrominated Diphenylether (PBDE) Flame Retardants and Thyroid Hormone

during Pregnancy

<http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F\

10.1289%2Fehp.1001905>

Polybrominated diphenyl ethers induce developmental neurotoxicity in a

human in vitro model: evidence for endocrine disruption.

<http://www.ncbi.nlm.nih.gov/pubmed/20368126>

Schreiber T, Gassmann K, Götz C, Hübenthal U, Moors M, Krause G, Merk

HF, Nguyen NH, Scanlan TS, Abel J, Rose CR, Fritsche E.

Environ Health Perspect. 2010 Apr;118(4):572-8.

Association of low-dose exposure to persistent organic pollutants with

global DNA hypomethylation in healthy koreans.

<http://www.ncbi.nlm.nih.gov/pubmed/20064773>

Kim KY, Kim DS, Lee SK, Lee IK, Kang JH, Chang YS, s DR, Steffes M,

Lee DH.

Environ Health Perspect. 2010 Mar;118(3):370-4.

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*/Autism: instructive Pubmed search:/*

hypomethylat* AND autis*