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Dear Kate--

It takes up to eight weeks to see a complete and full

reaction to a new thyroid medication or a new dosage.

If she gets tested after three weeks, she won't have a

true picture of her current dosage, and she might go

hyper if she adds additional medication.

Best--

Courtenay.

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Courtenay,

I've never heard eight week. T4 takes 3-4 weeks in the system.

Kate

*

Edited by moderator to respond to above statement.

*It takes 6-8 weeks for T4 levels to stabilize on a new dose. T3 levels are

stable at about 3 weeks, but since everything is connected, a new T3 dose may

change your T4 levels. For that reason, unless you suspect overmedication, it is

a good idea to wait 6-8 weeks to see the full impact of the new dose.*

At 01:04 PM 10/13/2006, you wrote:

>Dear Kate--

>

>It takes up to eight weeks to see a complete and full

>reaction to a new thyroid medication or a new dosage.

>If she gets tested after three weeks, she won't have a

>true picture of her current dosage, and she might go

>hyper if she adds additional medication.

>

>Best--

>

>Courtenay.

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  • 5 months later...
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Hey Casey, you know I kind of had a strong feeling about this, from what

you've told me. The ? now is what are they gonna do about it, for you,

besides the pregnenolone? I know that it is the major precursor, but why

don't they just go for the direct thing, hydrocortisone? Did the doc say

why or what?

Lab results

> Ok friends and family

> I went to the doc today and received my Saliva test results. It

> seems I have a large depletion in my cortisol production and so here

> are some numbers for those who care:

>

> TAP Free Cortisol Rhythm Range

> 7-8am 7 13-24

> 11-12 2 5-10

> 4-5 1 3-8

> 11-12 pm 1 1-4

>

> Coritsol Burden 11 23-42

>

> Progesterone 16 22-100 Optimal

> 101-130 Borderline

> >130 Elevated

>

> Total Salivary SIgA 13 Normal 25-60

> Borderline 20-25

>

> Gliadin Ab, SIgA 14 13-15 Borderline

> >15 Positive

>

> DHEA 5 3-10

>

> Insulin <3 Normal 3-12

> Optimal 5-20

> We are not worried about this one as I am not diabetic

>

> So for now we are going to try Pregnenolone to help my body make

> cortisol on its own and see how it goes.

>

> If I can get my adrenals working again, then some of my weird

> symptoms might clear up, and I will feel better (stop shaking would

> be good)

>

> I have to get some blood work done, and I am hoping insurance will

> still cover. It should.

>

> Ok, that's what I know

>

> Casey

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She did not mention Hydrocortisone, at least I don't remember that being mentioned. The Diagnos lab sent back some recommendations on what they think would help, and Pregnenolone was the main thing, then some other minerals and such and then Cortisol or Licorce. wrote: Hey Casey, you know I kind of had a strong feeling about this, from what you've told me. The ? now is what are they gonna do about it, for you, besides the pregnenolone? I know that it is the major precursor, but why don't they just go for the direct thing, hydrocortisone? Did the doc say why or what? Lab results> Ok friends and family> I went to the doc today and received my Saliva test results. It> seems I have a large depletion in my cortisol production and so here> are some numbers for those who care:>> TAP Free Cortisol Rhythm Range> 7-8am 7 13-24> 11-12 2 5-10> 4-5 1 3-8> 11-12 pm 1 1-4>> Coritsol Burden 11 23-42>> Progesterone 16 22-100 Optimal> 101-130 Borderline> >130 Elevated>> Total Salivary SIgA 13 Normal 25-60> Borderline 20-25>> Gliadin Ab, SIgA 14 13-15 Borderline> >15 Positive>> DHEA 5 3-10>> Insulin <3 Normal 3-12> Optimal 5-20> We are not worried about this one as I am not diabetic>> So for now we are going to try Pregnenolone to help my body make> cortisol on its own and see how it

goes.>> If I can get my adrenals working again, then some of my weird> symptoms might clear up, and I will feel better (stop shaking would> be good)>> I have to get some blood work done, and I am hoping insurance will> still cover. It should.>> Ok, that's what I know>> Casey

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Cortisol is hydrocortisone. Some docs would rather give the prohormones DHEA or pregnenalone (or progesterone) to see if they will convert to cortisol among other things. Hypo/Hashi patients are unfortunately notorious for failing to convert a variety of hormones or to convert along unexpected pathways. For that reason, all sex and adrenal hormones should be tested on a regular basis, even if you are only taking one prohormone. Casey Finigan wrote: She did not mention Hydrocortisone, at least I don't remember that being mentioned. The Diagnos lab sent back some

recommendations on what they think would help, and Pregnenolone was the main thing, then some other minerals and such and then Cortisol or Licorce. wrote: Hey Casey, you know I kind of had a strong feeling about this, from what you've told me. The ? now is what are they gonna do about it, for you, besides the pregnenolone? I know that it is the major precursor, but why don't they just go for the direct thing, hydrocortisone? Did the doc say why or what? Lab results> Ok

friends and family> I went to the doc today and received my Saliva test results. It> seems I have a large depletion in my cortisol production and so here> are some numbers for those who care:>> TAP Free Cortisol Rhythm Range> 7-8am 7 13-24> 11-12 2 5-10> 4-5 1 3-8> 11-12 pm 1 1-4>> Coritsol Burden 11 23-42>> Progesterone 16 22-100 Optimal> 101-130 Borderline> >130 Elevated>> Total Salivary SIgA 13 Normal 25-60> Borderline 20-25>> Gliadin Ab, SIgA 14 13-15 Borderline> >15 Positive>> DHEA 5 3-10>> Insulin <3 Normal 3-12> Optimal 5-20> We are not worried about this one as I am not diabetic>> So for now we are going to try Pregnenolone to help my body make> cortisol on its own and see how it goes.>> If I can get my adrenals working again, then some

of my weird> symptoms might clear up, and I will feel better (stop shaking would> be good)>> I have to get some blood work done, and I am hoping insurance will> still cover. It should.>> Ok, that's what I know>> Casey

Be a PS3 game guru.Get your game face on with the latest PS3 news and previews at Yahoo! Games.

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Ok, well it's all greek to me. I truly believe I am also Hashi but I am having trouble convincing the doctor. So here's my plan, I take new blood tests this morning, there is a whole list of things and I will start the pregnenolone. When I get ahold of my lab results, probably not for a couple of weeks, I will know more about thryoid numbers again and I can go from there. If she doesn't want to treat me, then I will have to find someone else. Jan wrote: Cortisol is hydrocortisone. Some docs would rather give the prohormones DHEA or pregnenalone (or progesterone) to see if they will convert to

cortisol among other things. Hypo/Hashi patients are unfortunately notorious for failing to convert a variety of hormones or to convert along unexpected pathways. For that reason, all sex and adrenal hormones should be tested on a regular basis, even if you are only taking one prohormone. Casey Finigan wrote: She did not mention Hydrocortisone, at least I don't remember that being mentioned. The Diagnos lab sent back some recommendations on what they think would help, and Pregnenolone was the main thing, then some other minerals and such and then Cortisol or Licorce. wrote: Hey Casey, you know I kind of had a strong feeling about this, from what you've told me. The ? now is what are they gonna do about it, for you, besides the pregnenolone? I know that it is the major precursor, but why don't they just go for the direct thing, hydrocortisone? Did the doc say why or what? Lab results> Ok friends and family> I went to the doc today and received my Saliva test results. It> seems I have a large depletion in my cortisol production and so here> are some numbers for those who care:>> TAP Free Cortisol Rhythm Range> 7-8am 7 13-24> 11-12 2 5-10> 4-5 1

3-8> 11-12 pm 1 1-4>> Coritsol Burden 11 23-42>> Progesterone 16 22-100 Optimal> 101-130 Borderline> >130 Elevated>> Total Salivary SIgA 13 Normal 25-60> Borderline 20-25>> Gliadin Ab, SIgA 14 13-15 Borderline> >15 Positive>> DHEA 5 3-10>> Insulin <3 Normal 3-12> Optimal 5-20> We are not worried about this one as I am not diabetic>> So for now we are going to try Pregnenolone to help my body make> cortisol on its own and see how it goes.>> If I can get my adrenals working again, then some of my weird> symptoms might clear up, and I will feel better (stop shaking would> be good)>> I have to get some blood work done, and I am hoping insurance will> still cover. It should.>> Ok, that's what I know>> Casey Be a PS3 game guru.Get your game face on with the latest PS3 news and previews at Yahoo! Games.

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I took pregnenalone for a few months. It made my periods come every 2-3 weeks. I have endometriosis so the nutritionist thinks my body was just converting it all to estrogen....just a thought. I would like to try it again if needed after do sex hormone saliva test with next period.

Ok friends and familyI went to the doc today and received my Saliva test results. It seems I have a large depletion in my cortisol production and so here are some numbers for those who care:TAP Free Cortisol Rhythm Range

7-8am 7 13-2411-12 2 5-104-5 1 3-811-12 pm 1 1-4Coritsol Burden 11 23-42Progesterone 16 22-100 Optimal101-130 Borderline>130 ElevatedTotal Salivary SIgA 13 Normal 25-60

Borderline 20-25Gliadin Ab, SIgA 14 13-15 Borderline>15 PositiveDHEA 5 3-10Insulin <3 Normal 3-12 Optimal 5-20We are not worried about this one as I am not diabeticSo for now we are going to try Pregnenolone to help my body make cortisol on its own and see how it goes. If I can get my adrenals working again, then some of my weird symptoms might clear up, and I will feel better (stop shaking would be good)I have to get some blood work done, and I am hoping insurance will still cover. It should. Ok, that's what I knowCasey -- CauleyHome

Cell

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Yep, I started to say (before I read the second sentence, that is), it's converting it all to estrogen, more than likely. That's the trouble----when we're taking a hormone that needs to be converted to something else, we don't always know which one it's going to convert to. Since I had fibroid tumors and the signs of mild endometriosis, with those long heavy periods, and was making no progesterone (yrs ago before I had it all taken out), it was very likely that I had (and may always have, I don't know) an abundance of estrogen(s). I would say that now (20 yrs later) it has dwindled somewhat, due to all this dryness and other symptoms, but I would never say that I don't have enough of it in there because the DHEA I was taking made me very sluggish after awhile, heart rate slowed down considerably, which kind of made me think that my thyroid hormones were being "blocked" by something. Want go guess what that something was? After being off of it for just a few days to over a week or so, suddenly I was having those exact symptoms any more. Just guessing, but I think that probably almost any of these indirect methods are going to convert to estrogen, but I don't have recent labs to prove it, just a good gut instinct about my body. I need those saliva tests and have procrastinated far too long about it.

Re: Lab results

I took pregnenalone for a few months. It made my periods come every 2-3 weeks. I have endometriosis so the nutritionist thinks my body was just converting it all to estrogen....just a thought. I would like to try it again if needed after do sex hormone saliva test with next period.

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  • 1 month later...
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I met with Dr. Manso today. I had blood work done 3 weeks ago. At that time we lowered my synthroid to 75 mcg and kept cytomel at 10 mg per day. I lowered t4 as I was having hyper symptoms. Haven't noticed much difference but I have been sick with strep throat and now a sinus infection, so very tired these days.

Anyway, had cortisol saliva test done. The result was 47 out of 23-42. So, I am overproducing cortisol. This may be due to stress or, I think, my severe allergies, per dr. I am having sinus surgery end of march so will see how that affects it.

Any comments on my high cortisol?

I also am anemic, very low iron. Will remember better to take my slow FE and see if that helps. Also, need to take my calcium and magnesium better. Good news was my cholesterol was low and HDL is mid-range.

He also wants me to do the master cleanser to rid my body of toxins. Have done something similar before when started yeast free diet. It was hard but I am willing to give this a try. If I can lose some weight, then will retest for sleep apnea to see if it goes away.

Thanks,

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