Re: [autism-challenge] autism-autoimmune processes related to chronic bacterial infection

[Guest guest]

Is this treatment widely available?

Rose

[autism-challenge] autism-autoimmune processes related to

chronic bacterial infection

World J Biol Psychiatry. 2002 Jul;3(3):162-6.

Treatment of late onset autism as a consequence of probable

autommune processes related to chronic bacterial infection.

Matarazzo EB.

Department of Psychiatry, School of Medicine, University of Sao

o, Brazil. eneidam_br@...

Two cases are described of children who at first developed

normally, but before the age of three developed autistic symptoms

following the reactivation of a chronic oto-rhinolaryngologic infection.

The clinical and laboratory data of the cases support the aetiological

hypothesis of an autoimmune process. Adrenocorticotrophic hormone

(ACTH), prescribed in the first months of the disease, cured one case.

The other patient, who was two years old when autistic symptoms appeared

and was treated only six years later, showed a partial but definitive

improvement with the immunosuppressive treatment. This report proposes

that reactivation of a chronic bacterial infection be included among the

aetiologies of Late Onset Autism, and demonstrates that, when the

aetiological hypothesis of an autoimmune process based on clinical and

laboratory data is considered, an immunosuppressive treatment,

particularly with ACTH, can be very effective and also safe.

PMID: 12478882 [PubMed - indexed for MEDLINE]

* autism-challenge/

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[Guest guest]

This article brought back many memories. As a two year old, Lindsey (male,

age 22 yrs) had uncontrollable seizures, was failure to thrive. After a

dismal visit to Canada's renowned Sick Kids, we were stretched to find some

answers. We took Lindsey to Mayo Clinic. A battery of tests and two weeks

hospitalization and huge bill, we came home with daily injections of ACTH -

not ever really knowing why. These were injected for a full year with

unknown results. They didn't seem to bring about any huge " ah ha " that I

can recall (though many years later) I wish now to dig up those medical

reports and possibly communicate with those doctors to learn more. Despite

a very rocky first five years (ie seizures, gastrostomy etc) Lindsey has

thrived " without ever speaking a word " Still lots of life is thrown at us

and him - getting settled in a new " A " friendly home with others with

similar abilities and educating the caregivers in providing the much needed

respect. If anyone can provide further light on ACTH's use way back when,

please post. Thanks Deb

[autism-challenge] autism-autoimmune processes related to

chronic bacterial infection

> World J Biol Psychiatry. 2002 Jul;3(3):162-6.

>

> Treatment of late onset autism as a consequence of probable

> autommune processes related to chronic bacterial infection.

>

> Matarazzo EB.

>

> Department of Psychiatry, School of Medicine, University of Sao

> o, Brazil. eneidam_br@...

>

> Two cases are described of children who at first developed

> normally, but before the age of three developed autistic symptoms

> following the reactivation of a chronic oto-rhinolaryngologic infection.

> The clinical and laboratory data of the cases support the aetiological

> hypothesis of an autoimmune process. Adrenocorticotrophic hormone

> (ACTH), prescribed in the first months of the disease, cured one case.

> The other patient, who was two years old when autistic symptoms appeared

> and was treated only six years later, showed a partial but definitive

> improvement with the immunosuppressive treatment. This report proposes

> that reactivation of a chronic bacterial infection be included among the

> aetiologies of Late Onset Autism, and demonstrates that, when the

> aetiological hypothesis of an autoimmune process based on clinical and

> laboratory data is considered, an immunosuppressive treatment,

> particularly with ACTH, can be very effective and also safe.

> PMID: 12478882 [PubMed - indexed for MEDLINE]

> * To visit your group on the web, go to:

> autism-challenge/

> Responsibility for the content of this message lies strictly with

> the original author, and is not necessarily endorsed by or the

> opinion of the Research Institute.

>

> To visit your group on the web, go to:

> /

>

>