Digest 1c. Re: Ammann essay, location of PDF for printing...

[Guest guest]

Steve (T),

As a sensitized person, with absolutely no credentials and no

science to back up my opinion, my answer is yes, there are two

additional processes I'd hypothesize.

4. Direct modulation, in the bloodstream, of the level of one or

more substances used by neurons, such as ion channel ions,

neurotransmitters, etc. This typically occurs in sensitized

individuals, not the general population. For plausibility I point

out that these substances are typically in the bloodstream at

concentrations of 1 part in 10^10 to 1 part in 10^12, so nanograms

of a contaminant reaching the bloodstream would be significant

unless regulated by some body mechanism.

Although I am primarily MCS and tolerate most molds, I have had

experiences since being sensitized in which exposure to particular

molds noticeably but subjectively impacted the operation of my

nervous system, in a reaction which cleared rapidly when leaving the

area where the mold was. Although I claim no expertise, from my

reading there is no known allergic reaction which clears in less

than 2 hours. Likewise it takes 2 hours just to get the body's

blood supply through the kidneys or liver (once, on average).

Occupying a nervous system receptor the way alcohol or an opiate

does likewise does not clear quickly. Almost a decade ago I reached

the conclusion that none of the mechanisms in the literature could

explain what my family and I were experiencing -- but as a guy who

used to design computers the behavior is very much like what a

computer chip does when the power at its pins is " noisy " .

5. Autoimmune reactions, in which something the mold put into the

environment (could be half digested building materials, not limited

to something the mold directly secreted) got into the bloodstream,

acting as a hapten landed on a circulating protein or other

structure, and was attacked by the immune system. I hypothesize

this is the mechanism of sensitization for #4.

Steve Chalmers

stevec@...

>

> In a message dated 12/18/2007 11:18:38 AM Eastern Standard Time,

> aahavics@... writes:

> > " Molds and other fungi may adversely affect human health through

three

> > processes: 1) allergy; 2) infection; and 3) toxicity. "

> >

> Does chemical sensitization to bioaerosols and MVOCs fall into

category 1 or

> 3? Or should a 4th category be added?

>

> Steve Temes

>