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Klaire Labs makes P5P Plus Magnesium, you can order

from familypharmacy.net without docs script. Juli

--- <slethnobotanist@...> wrote:

> Anyone know of a good B6 supplement?

>

>

> --

> Life isn't static. People change. Circumstances

> change. What may have been true six months

> or a year ago may no longer be true now.

> Maybe a loved one got sick and died at a

> tender age...Maybe they ran into an old high

> school buddy who still looks great...At any rate

> what they couldn't hear before rings true to them

> now. So don't despair. Stick to the task. You will

> eventually find yourself surrounded by people who

> do care about good food and see it as a

> legitimate avenue to great health.

>

> Winning the War on Good Food

> http://www.warongoodfood.com

>

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On 11/24/05, Juli <rank35@...> wrote:

> Klaire Labs makes P5P Plus Magnesium, you can order

> from familypharmacy.net without docs script. Juli

Thanks ,

But I can't access Klaire labs without an online code.

--

Life isn't static. People change. Circumstances

change. What may have been true six months

or a year ago may no longer be true now.

Maybe a loved one got sick and died at a

tender age...Maybe they ran into an old high

school buddy who still looks great...At any rate

what they couldn't hear before rings true to them

now. So don't despair. Stick to the task. You will

eventually find yourself surrounded by people who

do care about good food and see it as a

legitimate avenue to great health.

Winning the War on Good Food

http://www.warongoodfood.com

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  • 1 month later...

On 1/5/06, Idol <Idol@...> wrote:

> -

>

> >Anyone know of a good B6 supplement?

>

> This comes rather late, but bulk pyridoxamine at VitaSpace.

>

> http://www.vitaspace.com/laboratory_chemicals_order_page.htm

>

> $2/g.

>

> It's under " Lab Chemicals " to avoid trouble with the FDA, but it's USP grade.

>

Thanks . As you may or may not know my sister recently had a

mini-stroke and someone posted an article detailing how B6 can be

helpful.

--

Life isn't static. People change. Circumstances

change. What may have been true six months

or a year ago may no longer be true now.

Maybe a loved one got sick and died at a

tender age...Maybe they ran into an old high

school buddy who still looks great...At any rate

what they couldn't hear before rings true to them

now. So don't despair. Stick to the task. You will

eventually find yourself surrounded by people who

do care about good food and see it as a

legitimate avenue to great health.

Winning the War on Good Food

http://www.warongoodfood.com

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-

>Thanks . As you may or may not know my sister recently had a

>mini-stroke and someone posted an article detailing how B6 can be

>helpful.

Yikes, I had no idea. I'm very sorry to hear that. Unfortunately, a

lot of the best things that can be done for a stroke have to be done

immediately, but even so, there are a lot of things she can do. I

can point you in a bunch of directions if you'd like.

-

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  • 2 weeks later...

On 1/6/06, Idol <Idol@...> wrote:

> -

>

> >Thanks . As you may or may not know my sister recently had a

> >mini-stroke and someone posted an article detailing how B6 can be

> >helpful.

>

> Yikes, I had no idea. I'm very sorry to hear that. Unfortunately, a

> lot of the best things that can be done for a stroke have to be done

> immediately, but even so, there are a lot of things she can do. I

> can point you in a bunch of directions if you'd like.

>

Sounds good. Of course you can probably guess that I loaded her up

with info, probably too much, but it never hurts to have as much input

as possible.

I have already decided that I'm going to have give her a care package

of stuff as soon as I can afford it, and probably go back to buying a

good chunk of their food when I'm out shopping, which I did when she

was pregnant and actively inquiring of me as to the best way to eat

while pregnant.

I used to do this for my entire family but then decided one day to

stop and see what they would do if I didn't bring the stuff to them.

Well the answer to that is NOTHING, lol, for the most part. I look in

their respective refrigerators and my heart sinks. Oh well. I will do

what I can do.

--

I first met her...in the Student Union at the University...sitting

across and down the table from each other. Our eyes met and that was

it. I was lost immediately in her soulful gaze (which I remember

vividly and tearfully even now) and was drawn inexorably from that

very moment into a love so certain that I never doubted anything about

it, other than the improbability that she would put up with me.

Things worked out. Glory to God!

-Mark Gilstrap

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-

>Sounds good.

Besides all the usual dietary changes -- which are more necessary

than ever -- particular attention should be paid to foods that

nourish the brain. Liver is good, abundant quantities of the highest

quality raw egg yolks are good, etc. And some supplements, if

they're affordable, could help. CDP choline (AKA citicoline) could

be very useful. Here are a few links.

http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/cdp_0064.shtml

http://www.aor.ca/related_research/cdp-citicoline.php

http://www.aor.ca/abstracts/cytidine_5-diphosphocholine.php

How much supplementation is actually possible in this

situation? There are other useful possibilities I can recommend.

> Of course you can probably guess that I loaded her up

>with info, probably too much, but it never hurts to have as much input

>as possible.

I'm afraid I have to disagree with you there. A lot of people just

shut everything out when given too much input. Often it's better to

tease out someone's interest with only a little info at first.

>I look in

>their respective refrigerators and my heart sinks. Oh well. I will do

>what I can do.

Yeah, I know the feeling.

-

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On 1/15/06, Idol <paul_idol@...> wrote:

> How much supplementation is actually possible in this

> situation? There are other useful possibilities I can recommend.

Do you mean budgetwise? I think if she was convinced something was

useful it wouldn't matter to her.

> > Of course you can probably guess that I loaded her up

> >with info, probably too much, but it never hurts to have as much input

> >as possible.

>

> I'm afraid I have to disagree with you there. A lot of people just

> shut everything out when given too much input. Often it's better to

> tease out someone's interest with only a little info at first.

Oh no we are agreement here. I meant input to me, which I can then

filter to her. I already gave her as much as thought she could handle

based on what she was asking me and what I know she would most likely

be receptive to and then do.

--

I first met her...in the Student Union at the University...sitting

across and down the table from each other. Our eyes met and that was

it. I was lost immediately in her soulful gaze (which I remember

vividly and tearfully even now) and was drawn inexorably from that

very moment into a love so certain that I never doubted anything about

it, other than the improbability that she would put up with me.

Things worked out. Glory to God!

-Mark Gilstrap

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-

>Do you mean budgetwise? I think if she was convinced something was

>useful it wouldn't matter to her.

Budget and willingness (dedication, really) are both concerns.

One of the main ways a stroke causes long-term

problems is free radical damage. That's why

rapid antioxidant intervention can be enormously

helpful. Of course by now it's too late, but I'd

still suggest both an antioxidant diet and antioxidant supplementation.

The other main problem is attempting to rebuild

what was damaged and destroyed. As I mentioned

before, CDP choline is very likely useful for

this. Alpha GPC choline might also be very

helpful, but in this case I'd probably recommend

either CDP or CDP and GPC, but not only GPC. Not

positive about that, though; I'd have to look

into the issue specifically as it applies to stroke victims further.

Lithium orotate might well also be very helpful.

http://www.newswithviews.com/Howenstine/james11.htm

Modest cycled pregnenolone supplementation might

also be worth a shot for nerve regrowth.

http://www.tours.inra.fr/societeneuroendocrino/colloques/Lille/conferences/Schum\

acher.htm

Acetyl l-carnitine is tremendously useful for all

things brain. I'm not even sure where to start

you with references because the universe of

research and applications on ALCar is so vast, but here's one.

http://www.annalsnyas.org/cgi/content/abstract/1053/1/153

Newer ALCar derivatives like acetyl l-carnitine

arginate might also be worth looking into, but

she should first try plain ALCar.

Bear in mind that anyone taking any form of

carnitine supplementation should also take R-ALA,

because carnitine increase mitochondrial energy

output and therefore free radical output. R-ALA

is one of the only antioxidants that functions in

the mitochondria and handles this problem. Don't

interpret this as a reason to avoid ALCar, though

-- it's a fantastic supplement, and though

expensive, R-ALA is one of the best things anyone

could take in any event, and I'd absolutely recommend it for your sister.

Methylcobalamin also facilitates neuron repair,

and since glial cells are particularly burdened

with cleanup and repair after a stroke, a high

attack dose of methylcobalamin (50mg/day or even

more) could be extremely helpful.

High doses of royal jelly could also be very

helpful based on this mouse study. (I figure you'll like this suggestion!)

>Oral Administration of Royal Jelly Facilitates

>mRNA Expression of Glial Cell Line-Derived

>Neurotrophic Factor and Neurofilament H in the

>Hippocampus of the Adult Mouse Brain

>

>Manabu Hashimoto,1 Masafumi Kanda,1 Kumiko

>Ikeno,2 Yoshirou Hayashi,3 Tadashi Nakamura,2

>Yoshinobu Ogawa,3 Hidefumi Fukumitsu,1 Hiroshi Nomoto,1 and Shoei Furukawa1,†

>

>1Laboratory of Molecular Biology, Gifu

>Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan

>2Japan Beekeeping Co., Ltd., Kanofujicho, Gifu 500-8471, Japan

>3Zeria Healthway Co., Ltd., Tomizawa-cho,

>Nihonbashi, Chuo-ku, Tokyo 103-0006, Japan

>

>Royal jelly (RJ) is known to have a variety of

>biological activities toward various types of

>cells and tissues of animal models, but nothing

>is known about its effect on brain functions.

>Hence, we examined the effect of oral

>administration of RJ on the mRNA expression of

>various neurotrophic factors, their receptors,

>and neural cell markers in the mouse brain. Our

>results revealed that RJ selectively facilitates

>the mRNA expression of glial cell line-derived

>neurotrophic factor (GDNF), a potent

>neurotrophic factor acting in the brain, and

>neurofilament H, a specific marker predominantly

>found in neuronal axons, in the adult mouse

>hippocampus. These observations suggest that RJ

>shows neurotrophic effects on the mature brain

>via stimulation of GDNF production, and that

>enhanced expression of neurofilament H mRNA is

>involved in events subsequently caused by GDNF.

>RJ may play neurotrophic and/or neuroprotective

>roles in the adult brain through GDNF.

I could go on and on and on, but there's a limit

to how much most people are willing to try, and

you also never really know what's going to help a

specific individual until trying it. If you want

more suggestions, though, just say the word.

Also possibly of importance, your sister could

save a huge boatload of money on many of these

supplements by purchasing bulk powders instead of

commercial encapsulations, but that pretty much

requires a lab scale to measure doses (on the

order of $100) and more interest and commitment

than the vast majority of people have. I can

point you to some good sources, though, if it's a viable option.

-

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>Do you mean budgetwise? I think if she was convinced something was

>useful it wouldn't matter to her.

A couple more I should've included in my previous post:

Bacopa. Upregulates superoxide dismutase. Very useful.

NAC (N-Acetyl Cysteine). Precursor to glutathione. Should be taken

along with any SOD-upregulator to keep the body's antioxidant systems balanced.

-

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,

>

>Bacopa. Upregulates superoxide dismutase. Very useful.

>

>NAC (N-Acetyl Cysteine). Precursor to glutathione. Should be taken

>along with any SOD-upregulator to keep the body's antioxidant

>systems balanced.

,

What about SOD itself, plus catalase and methionine reductase? I was under

the impression that these work together with glutathine peroxidase. And what

about the antioxidant network? I guess I'm just not clear on why just an SOD

upregulator and glutathione would constitute a " balanced " antioxidant

system.

And what exactly is an SOD-upregulator? Google wasn't very helpful with

this.

I'm currently take NAC for my liver, so I'm very interested in your

information on this.

BTW, I see iherb has bacopa from Himalaya USA for a good price. Bacopa seems

like the only non-drug SOD-upregulator. Is that correct?

Suze Fisher

Lapdog Design, Inc.

Web Design & Development

http://members.bellatlantic.net/~vze3shjg

Weston A. Price Foundation Chapter Leader, Mid Coast Maine

http://www.westonaprice.org

----------------------------

" The diet-heart idea (the idea that saturated fats and cholesterol cause

heart disease) is the greatest scientific deception of our times. " --

Mann, MD, former Professor of Medicine and Biochemistry at Vanderbilt

University, Tennessee; heart disease researcher.

The International Network of Cholesterol Skeptics

<http://www.thincs.org>

----------------------------

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Suze-

>What about SOD itself

It's not absorbed. Similar problem to taking oral glutathione itself

rather than NAC.

>plus catalase

I stupidly forgot to mention catalase. SOD, catalase and glutathione

are the three which need to be carefully balanced because they're all

interrelated. SOD is great, but extra SOD activity yields extra

peroxide, and if there's not enough catalase and glutathione

peroxidase around to turn the peroxide into water directly, some of

the peroxide will go through the Fenton reaction and turn into

hydroxyl radicals, which are extremely potent.

<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=pubmed & dopt=Abstr\

act & list_uids=7492966 & query_hl=1 & itool=pubmed_docsum>

I don't know offhand of any dramatic way to genuinely upregulate

catalase production in the same way that bacopa, for example,

upregulates SOD or even that taking NAC and getting adequate dietary

or supplemental selenium stimulates heightened glutathione peroxidase

production, but adequate dietary iron is certainly required -- which

has had me wondering what the influence of lactoferrin on catalase

production is.

I think selenium is also important for producing catalase, and copper

and zinc and manganese are required for SOD, so getting enough

minerals is obviously important.

>and methionine reductase?

I'm less familiar with that one, but my understanding is that it's

more of a specialized antioxidant as compared to the fundamental

pillars of antioxidant functionality which SOD, catalase and glutathione are.

>I guess I'm just not clear on why just an SOD

>upregulator and glutathione would constitute a " balanced " antioxidant

>system.

I was careless with my wording. It's not that those two by

themselves encompass balancing all antioxidant activity. It's that

SOD, catalase and glutathione are extremely powerful -- much more so

than many other antioxidants -- and there's an important reason to

balance catalase and glutathione with SOD so that the Fenton reaction

doesn't wind up screwing you over with lots of OH-. It's a lot

easier to boost glutathione than it is to boost catalase AFAIK, so

that's what I mentioned.

>And what exactly is an SOD-upregulator?

Something that boosts the body's production of superoxide dismutase.

>I'm currently take NAC for my liver, so I'm very interested in your

>information on this.

It's all over the net -- well-established. E.g.:

<http://www.wholehealthmd.com/refshelf/substances_view/1,1525,809,00.html>

>BTW, I see iherb has bacopa from Himalaya USA for a good price.

You can get it cheaper as a bulk powder.

>Bacopa seems

>like the only non-drug SOD-upregulator. Is that correct?

AFAIK, though I guess it depends on whether you'd call adequate

supplies of necessary ingredients an " upregulator " .

Speaking of which, SOD is another one of those bloody single terms

for multiple items. Offhand I'm not positive about exactly how many

forms of SOD there are, but I think there are two: the mitochondrial

form, which uses manganese, and the cellular form, which uses copper and zinc.

-

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Suze-

>What about SOD itself, plus catalase and methionine reductase?

Previously I'd only read about methionine reductase in relation to

mercury toxicity and radiation, but I see it deals with hydroxyl

radicals, which suggests a strong relationship to the

SOD/catalase/glutathione system and potentially equal importance, at

least if it's present and active throughout the body. Do you know

whether it is? And if so, do you know how to ensure adequate

production? Just get enough dietary methionine -- and of course

enough dietary methylating factors to avoid a homocysteine problem?

-

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,

>> >Thanks . As you may or may not know my sister recently had a

>> >mini-stroke and someone posted an article detailing how B6 can be

>> >helpful.

I don't have any experience with this treatment personally, but Dr. Rind in

DC has an alternative stroke treatment that might be of interest to you in

your research. The website has a before and after video that looked very

encouraging. I see Dr. Rind for other problems but I have happened to see a

few stroke patients in his office. Twice I heard them/their family member

saying how happy they were with their progress.

http://www.drrind.com/vascular.asp

Best wishes to you and your sister,

Sharon

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