Guest guest Posted December 2, 2005 Report Share Posted December 2, 2005 Bulletin on the Rheumatic Diseases Volume 51, Number 3 Excerpt from " Myopathic Diseases " : Dermatomyositis in Adults. The clinical features of dermatomyositis in adults include all of those described for polymyositis plus cutaneous involvement. Gotron's papules -- symmetric lacey pink or violaceous raised or macular areas found on the dorsal aspect of interphalangeal joints, elbows, patellae, and malleoli -- are considered pathognomonic. Other skin changes include heliotrope discoloration of the eyelids; macular erythema of the posterior shoulders and neck (shawl sign), anterior neck and upper chest (V sign), face, and forehead; and dystrophic cuticles with periungual telangiectasias or abnormal nail fold capillaries. Muscle histology usually differs from that of polymyositis. The inflammatory infiltrate is perivascular in location and is composed of B and CD4+ lymphocytes. Capillary plugging and perifascicular atrophy are also observed (5). http://www.arthritis.org/research/Bulletin/vol51no3/51_3_ifm.asp Not an MD I'll tell you where to go! Mayo Clinic in Rochester http://www.mayoclinic.org/rochester s Hopkins Medicine http://www.hopkinsmedicine.org Quote Link to comment Share on other sites More sharing options...
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