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new studyhttp://www.ncbi.nlm.nih.gov/pubmed?term=PMID%3A%2021279430Behav Genet. 2011 May;41(3):381-93. doi: 10.1007/s10-3. Epub 2011 Jan 29.Relationship between brain and cognitive processes in Down syndrome.Menghini D, Costanzo F, Vicari S.SourceDepartment of Neuroscience,

Children's Hospital Bambino Gesù, Rome, Italy.AbstractWe

investigated regional grey matter (GM) density in adolescents with Down

syndrome (DS) compared to age-matched controls and correlated MRI data with neuropsychological measures in the DS group. Inter-group comparisons documented several GM concentration abnormalities in the participants with DS compared to controls. In the adolescents with DS, intra-group results also showed associations between regional GM density

and the neuropsychological measures considered. In particular, GM density of the cerebellum and middle and inferior temporal gyrus was associated with linguistic measures. Short-term memory performances were

correlated with the inferior parietal lobule, insula, superior temporal

gyrus, medial occipital lobe, and cerebellum. Long-term memory abilities were correlated with GM density in the orbitofrontal cortex, lateral and medial temporal lobe regions, and anterior cingulum and visuo-perceptual abilities with GM density the left middle frontal gyrus. Results of this preliminary study are consistent with a not always efficient brain organization in DS.PMID:21279430 [PubMed - indexed for MEDLINE] all the Best in Health,Liora Pearlman , ModeratorMomPLEASE NOTE: I AM FIVE WEEKS BEHIND ON EMAIL. Please consider calling me at 5130 3931 or texting 139 1030 6022 if it is time

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