Re: Re: Ibuprofen/Pandas---Ibuprofen Does cross the BBB

[Guest guest]

Hi ,

My son only had a few strep infections but MANY sinus infections.Almost every

cold he gets turns into a sinus infection.

I didn't think my son could have PANDAS because almost my entire family has OCD(

not the sudden onset though), (and not the extreme " bad thoughts' kind,) but he

does.

I didn't know about the itchy skin, but my son is always itchy.

I wish you luck!

Hugs

judy

________________________________

To:

Sent: Wed, November 11, 2009 9:44:55 PM

Subject: Re: Re: Ibuprofen/Pandas---Ibuprofen Does cross the

BBB

 

,

Thanks for the support. I never considered PANDAS because he never had a known

Strep infection, though he had many sinus infections, and his father has OCD and

I assumed the genetic link.

He has had itchy skin on occasion. The problem he has had other symptoms on

occasion but what is coincidental and what is PANDAS? I feel it is a dilemma.

Tomorrow we'll find out.

Terry E.

RE: Re: Ibuprofen/Pandas- --Ibuprofen Does cross the

BBB

Terry,

Thank you for the information. Your sons ocd sounds a lot like my

daughters. She started her antibiotic tonight and I'm hopeful that we will

see results soon. One more thing that I just learned is that Strep can

cause itchy skin or itchy genitals. My daughter also had this symptom

recently and I dismissed it as her being obsessive. =( I had not heard

that before. I can't wait until she is feeling better!

I hope your son's blood test come out positive for pandas so you can get him

help. The ASO titers can vary. They can still be in the normal range and

they can still have PANDAS.

Ibuprofen DOES cross the BBB ( blood brain barrier):

http://www.molecula rstation. com/research/ brain-uptake- of-nonsteroidal-

anti-i<http://www.molecula rstation. com/research/ brain-uptake-

of-nonsteroidal- anti-i>

nflammatory- drugs-ibuprofen- flurbiprofen- and-indomethacin -16715377.

html<http

://www.molecularsta tion.com/ research/ brain-uptake- of-nonsteroidal-

anti-infla

mmatory-drugs- ibuprofen- flurbiprofen- and-indomethacin -16715377. html>

[Guest guest]

Terry,

My daughter never had a known case of strep either, yet she had some

antibodies, so clearly she had had it before. I've never been one to rush

my kids to the doctor but I'm rethinking that now. If he tests positive for

any antibodies at all, pursue the PANDAS route. They can put him on

prednisone for 5 days as a trial to see if symptoms abate or in our case

advil worked. Good luck

From:

[mailto: ] On Behalf Of Terry Rumas

Sent: Wednesday, November 11, 2009 9:45 PM

To:

Subject: Re: Re: Ibuprofen/Pandas---Ibuprofen Does cross

the BBB

,

Thanks for the support. I never considered PANDAS because he never had a

known Strep infection, though he had many sinus infections, and his father

has OCD and I assumed the genetic link.

He has had itchy skin on occasion. The problem he has had other symptoms on

occasion but what is coincidental and what is PANDAS? I feel it is a

dilemma.

Tomorrow we'll find out.