TAMIFLU, BMJ says DOES NOT WORK, COSTS A LOT

[Guest guest]

Tamiflu – does not work, costs a lotPublished December 11, 2009 A stunning indictment of Tamiflu by The Atlantic. ["The Truth about Tamiflu" <http://www.theatlantic.com/magazine/archive/2009/12/the-truth-about-tamiflu/7801/> sorry the link I posted at E-S list doesn't work any longer] A

trail of false evidence and marketing led the U.S. alone to spend $1.5 billion on stock piling the drug for pandemic preparation for things like SARS, and the whole world over $3 billion since H1N1 (swine flu) emerged.This week, the British medical journal BMJ published a multi-part investigation <http://www.bmj.com/cgi/content/full/339/dec07_2/b5106> that

confirms that the scientific evidence just isn’t there to show that Tamiflu prevents serious complications, hospitalization, or death in people that have the flu.Only 2 out of 10 studies backing Tamiflu were ever published in peer reviewed journals, and when they contacted those authors:One

author said he had lost track of the data when he moved offices and the

files appeared to have been discarded. The other said he’d never actually seen the data himself, and directed the Cochrane team to go directly to the company.But the worst evidence of all for me was this admission:two

former employees of Adis International, a large communications company,

came forward with documents showing they had ghostwritten some of the published studies of Tamiflu. One of the ghostwriters told the BMJ, “The

Tamiflu accounts had a list of key messages that you had to get in. It was run by the [Roche] marketing department

and you were answerable to them. In the introduction . . . I had to say what a big problem influenza is. I’d also have to come to the conclusion

that Tamiflu was the answer.â€Worse yet – is the supposed cure making things worse for patients?According

to an FDA spokesperson, side effects may include potentially fatal heart problems. If the drug is going to be used to prevent death, it seems reasonable to ask whether or not its potentially deadly side effects are outweighed by potential benefits. We asked the FDA whether it had required Roche to conduct an additional trial or trials looking at whether or not, on balance, the drug reduces more serious complications than it causes. This week, a spokesperson reported back that there has been no such request made

to Roche.I’ll leave it to The Atlantic to summarise:Tamiflu may not be doing much good for patients with the flu who take it, and it might be causing harm.Governments,

public health agencies, and international bodies such as the World Health Organization, have all based their decisions to recommend and stockpile Tamiflu on studies that had seemed independent, but had in fact been funded by the company and were authored almost entirely by Roche employees or paid academic consultants.Stunning investigative research by both The Atlantic and the BMJ. Well done.