Fw: ACANTHOSIS NIGRICANS & INSULIN INSULIN RESISTANCE

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----- Original Message -----

From: " sey (by way of ilena rose) " <fuchsmorrissey@...>

Sent: Saturday, December 15, 2001 1:49 PM

Subject: ACANTHOSIS NIGRICANS & INSULIN INSULIN RESISTANCE

> PLEASE POST We just found out yesterday evening that our 11 yr old who

has

> scleroderma, a swallowing disorder, allergies, an odd neurological

> disorder, an " acral bone dysplasia " of the hands/feet also now has

> acanthosis nigricans, AN.

> Our to date does have very black skin on her neck (not just a

dirty

> brown color like " classic " AN, acanthosis nigricans may present itself as,

> " dirty neck " ). She also has a very, very dark almost black color under her

> armpits, along with having skin tags in the armpit area. This child also

> has bronzed tissue, very varnished- like, shiny, glassy tissue that is

> extremely cracked year-round which presents itself as

> scleroderma/scleroderma-LIKE/morphea/morphea-LIKE (skin punch biopsy

taken

> 10-31-1996 at the age of 6 yrs old came back: morphea, consistant with)

and

> the dry tissue presents itself as icthyosis/icthyosis-LIKE tissue, (silica

> is a desiccant, long known to dry out) that may crack and bleed,

> year-round. This is NOT just a winter problem, but a year-round problem.

> This child had another high result concerning her insulin resistance.

> 's physician stated that to date does not have diabetes, but

> the acanthosis nigricans (AN) skin lesion may be an indicator of high

> diabetes risk, particularly in minority patient, that should NOT be

> overlooked by dermatologists. is not overweight, not a minority

> patient, is a child, but has gain some weight since I have been cutting up

> all her foods so she can swallow better. She is a small person

(dwarf-like,

> but not " classic dwarf " / not " classic " skeletal dysplasia -her case has

> been viewed at the Skeletal Dysplasia Registry at L. A., California by top

> genetics specialists) and I was hoping she could gain some to weight to

> grow, thus cutting up food so she could swallow better, (scleroderma

> swallowing problem) and grow.... Weight gain and loss may present the skin

> lesion of AN to appear lighter or darker depending on the person's weight

> ga! in or loss. NOTE INFO BELOW CONCERNING (AN) to educate and inform

> ones own self : " Acanthosis nigricans (AN) commonly manifests on the

skin

> in the collar area of neck. The hyperplastic skin lesion causes a

> darkening of the skin and is not bothersome to the patient. Presence of

> the lesion could indicate insulin resistance and hyperinsulinemia, which

> could be a marker for risk of developing non-insulin-dependent diabetes

> mellitus (NIDDM). It has been shown that patients with AN have the highest

> plasma insulin concentrations, which indicate they have the highest risk

> for NIDDM. Tests for AN: laboratory testing of the patient's fasting

plasma

> insulin concentration.The reason I care to share this is because this

> child's body is speaking great volumes IN HER YOUTH to an exerted/enhanced

> human immune response. I felt that one may learn from what is

> suffering from in her youth so they may NOT kick fully over into diabetes.

> Hope this is helpful in educating and informing. It is NOT intended to

> panic anyone, but to give more insight to what may happen with acanthosis

> nigricans (AN). MY own hope & prayer that one day those in medicine,

> science and research will indeed *****tailor medicines, vaccines, and YES

> medical devices (RE: breast implants for starters) to ones

genetics/genetic

> susceptibilities to further avoid medical adverse reactions.**** I am

> hoping and praying that with the genome that this will one day

happen....it

> is needed in our family and we are not along as there are many others like

> us in the world. As genetics is the foundation, not the " cause " . Yes, the

> " cause " would be the environmental trigger/time factor of exposure OR

> virus. That different triggers will indeed produce DIFFERENT SYMPTOMS,

> sometimes UNIQUE (like little is dealing/SUFFERING with

> daily)....unique symptoms, if one observes well with that open mind which

> is indeed valid to note/document, honestly in research, medicine and

> science. We are NOT just dealing with an idiocryncratic reaction here, but

> an overly, jumbled human immune response in a ! child who took massive

> " hits " from her mom (me) via the placental barrier through a process of

> microchimerism....Breast feeding, extra " hits " . Take care,

> Fuchs-sey, mother of three hypersilicemia daughters who were exposed

> to my extremely failed 3M/McGhan silicone gel and double breast implants.

> Breast implants pulled our trigger in our youth, via the placental barrier

> in these children.... is an end result of very flawed breast

> implants! <mailto:Fuchssey@...> Fuchssey@...

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