Re: I Quit Methotrexate 6 weeks ago.....When will the side effects subside??

September 30, 2005

Hi .

It is my understanding that MTX has a short half life, and the

majority of it is excreted within 24 hours. Since you were only on it

for 3 months, I believe

that it should be out of your system by now. RX list explains how MTX

is metabolized and excreted:

As far as the GI bleed, you had said before that you've been on

naprosyn for several years. Naprosyn's side effect is GI bleed. All

of the anti-inflammatory meds are hard on our intestines. I take

Naprosyn as well and my doctor prescribed Prilosec as a precaution.

Unfortunately once you have GI bleed, it takes awhile to heal

especially when you have to take meds that aggravate it. What does

your doctor say about it? How long were you off of it before starting

it again? Do you take anything for your stomach such as Prilosec?

MTX doesn't affect the eyes, but plaquenil does. You are supposed to

get regular eye exams while on plaquenil. Have you had one?

a

On Sep 30, 2005, at 8:33 AM, ju2346 wrote:

> Incredible, it caused a GI bleed which I am still battling, my hair

> is

> still falling out like rain, (even tho I take folic acid), I still

> experience the occasional " eye burning sensation " . I mean I have

> heard

> that I should expect it would be with me awhile, but 6 weeks? Is this

> normal? I tell you, I know methotrexate helps some, but for others

> its

> terrible. I have been on Humira for 6 weeks now, and I can say that

> so

> far, there is some improvement, still hoping for more. Also, I have

> been on Plaquenil for 4 weeks now. Can someone please tell me when

> will the side effects subside?? Thanx!!

>

September 30, 2005